ETV1 inhibition depressed M2 polarization of tumor-associated macrophage and cell process in gastrointestinal stromal tumor via down-regulating PDE3A

Lysyl oxidase expression is regulated by the H3K27 demethylase Jmjd3 in tumor-associated M2-like macrophages

(2020) Ryuhei Takemoto et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

Cooperation between ETS transcription factor ETV1 and histone demethylase JMJD1A in colorectal cancer

(2020) Sangphil Oh et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Potentiation of imatinib by cilostazol in sensitive and resistant gastrointestinal stromal tumor cell lines involves YAP inhibition

(2019) Pierre Vandenberghe et al.   Oncotarget

Targeting Tumor Microenvironment for Cancer Therapy

(2019) Catarina Roma-Rodrigues et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

TIM-3 dictates functional orientation of the immune infiltrate in ovarian cancer

(2019) Jitka Fucikova et al.   CLINICAL CANCER RESEARCH

Phosphodiesterase 3A Represents a Therapeutic Target that Drives Stem Cell–like Property and Metastasis in Breast Cancer

(2019) Na Hao et al.   MOLECULAR CANCER THERAPEUTICS

BRD4 promotes tumor progression and NF-κB/CCL2-dependent tumor-associated macrophage recruitment in GIST

(2019) Jianfeng Mu et al.   Cell Death & Disease

High density of CD68+ tumor-associated macrophages predicts a poor prognosis in gastric cancer mediated by IL-6 expression

(2018) Chong‑Yu Su et al.   Oncology Letters

Contribution to Tumor Angiogenesis From Innate Immune Cells Within the Tumor Microenvironment: Implications for Immunotherapy

(2018) Adriana Albini et al.   Frontiers in Immunology

Snail-overexpressing Cancer Cells Promote M2-Like Polarization of Tumor-Associated Macrophages by Delivering MiR-21-Abundant Exosomes

(2018) Chia-Hsin Hsieh et al.   NEOPLASIA

Long non-coding RNA NIFK-AS1 inhibits M2 polarization of macrophages in endometrial cancer through targeting miR-146a

(2018) Yun-xiao Zhou et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The Role of Toll-Like Receptor in Inflammation and Tumor Immunity

(2018) Xiaohong Cen et al.   Frontiers in Pharmacology

Anagrelide for Gastrointestinal Stromal Tumor

(2018) Olli-Pekka Pulkka et al.   CLINICAL CANCER RESEARCH

Gastrointestinal stromal tumor: clinicopathological characteristics and pathologic prognostic analysis

(2018) Chayanit Jumniensuk et al.   World Journal of Surgical Oncology

Targeting tumor cells based on Phosphodiesterase 3A expression

(2017) Madiha Nazir et al.   EXPERIMENTAL CELL RESEARCH

Phosphodiesterase 3A: a new player in development of interstitial cells of Cajal and a prospective target in gastrointestinal stromal tumors (GIST)

(2017) Pierre Vandenberghe et al.   Oncotarget

ETS-Transcription Factor ETV1 Regulates Stromal Expansion and Metastasis in Pancreatic Cancer

(2016) Steffen Heeg et al.   GASTROENTEROLOGY

Histone demethylase JMJD2A drives prostate tumorigenesis through transcription factor ETV1

(2016) Tae-Dong Kim et al.   JOURNAL OF CLINICAL INVESTIGATION

An inhibitor of the acetyltransferases CBP/p300 exerts antineoplastic effects on gastrointestinal stromal tumor cells

(2016) Meng-Li Gu et al.   ONCOLOGY REPORTS

Hypoxia promotes glioma-associated macrophage infiltration via periostin and subsequent M2 polarization by upregulating TGF-beta and M-CSFR

(2016) Xiaofan Guo et al.   Oncotarget

Emerging Agents for the Treatment of Advanced, Imatinib-Resistant Gastrointestinal Stromal Tumors: Current Status and Future Directions

(2015) Sebastian Bauer et al.   DRUGS

Current management of gastrointestinal stromal tumors: Surgery, current biomarkers, mutations, and therapy

(2015) Nakul Valsangkar et al.   SURGERY

Combined Inhibition of MAP Kinase and KIT Signaling Synergistically Destabilizes ETV1 and Suppresses GIST Tumor Growth

(2015) L. Ran et al.   Cancer Discovery

Abstract 4346: Novel discovery of miR-30e* regulating Bmi1 expression induced by tumor-associated macrophages in gastrointestinal cancer

(2015) Hidetaka Sugihara et al.   CANCER RESEARCH

Altered expression of ETV1 and its contribution to tumorigenic phenotypes in gastrointestinal stromal tumors

(2014) YAN ZHANG et al.   ONCOLOGY REPORTS

Exosome derived from epigallocatechin gallate treated breast cancer cells suppresses tumor growth by inhibiting tumor-associated macrophage infiltration and M2 polarization

(2013) Ji-Young Jang et al.   BMC CANCER

Anti-KIT monoclonal antibody inhibits imatinib-resistant gastrointestinal stromal tumor growth

(2013) Badreddin Edris et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cyclic nucleotide phosphodiesterase (PDE) isozymes as targets of the intracellular signalling network: benefits of PDE inhibitors in various diseases and perspectives for future therapeutic developments

(2011) Thérèse Keravis et al.   BRITISH JOURNAL OF PHARMACOLOGY

Role of PDE3A in regulation of cell cycle progression in mouse vascular smooth muscle cells and oocytes: implications in cardiovascular diseases and infertility

(2011) Najma Begum et al.   CURRENT OPINION IN PHARMACOLOGY

Overexpression of Full-Length ETV1 Transcripts in Clinical Prostate Cancer Due to Gene Translocation

(2011) Delila Gasi et al.   PLoS One

Incidence of Sarcoma Histotypes and Molecular Subtypes in a Prospective Epidemiological Study with Central Pathology Review and Molecular Testing

(2011) Françoise Ducimetière et al.   PLoS One

ETV1 is a lineage survival factor that cooperates with KIT in gastrointestinal stromal tumours

(2010) Ping Chi et al.   NATURE

Anti-inflammatory M2 type macrophages characterize metastasized and tyrosine kinase inhibitor-treated gastrointestinal stromal tumors

(2009) Minka van Dongen et al.   INTERNATIONAL JOURNAL OF CANCER