Lung neuroendocrine tumours: deep sequencing of the four World Health Organization histotypes reveals chromatin-remodelling genes as major players and a prognostic role forTERT,RB1,MEN1andKMT2D

Next-Generation Sequencing of Pulmonary Large Cell Neuroendocrine Carcinoma Reveals Small Cell Carcinoma-like and Non-Small Cell Carcinoma-like Subsets

(2016) N. Rekhtman et al.   CLINICAL CANCER RESEARCH

Mutational analysis of pulmonary tumours with neuroendocrine features using targeted massive parallel sequencing: a comparison of a neglected tumour group

(2015) Claudia Vollbrecht et al.   BRITISH JOURNAL OF CANCER

Well-Differentiated Neuroendocrine Tumors with a Morphologically Apparent High-Grade Component: A Pathway Distinct from Poorly Differentiated Neuroendocrine Carcinomas

(2015) L. H. Tang et al.   CLINICAL CANCER RESEARCH

Precision medicine at Memorial Sloan Kettering Cancer Center: clinical next-generation sequencing enabling next-generation targeted therapy trials

(2015) David M. Hyman et al.   DRUG DISCOVERY TODAY

Driver Gene Mutations of Non-Small-Cell Lung Cancer are Rare in Primary Carcinoids of the Lung: NGS Study by Ion Torrent

(2015) Gemma Armengol et al.   LUNG

Homologous-recombination-deficient tumours are dependent on Polθ-mediated repair

(2015) Raphael Ceccaldi et al.   NATURE

Comprehensive genomic profiles of small cell lung cancer

(2015) Julie George et al.   NATURE

What clinicians are asking pathologists when dealing with lung neuroendocrine neoplasms?

(2015) Giuseppe Pelosi et al.   SEMINARS IN DIAGNOSTIC PATHOLOGY

Clinical implications of genomic alterations in the tumour and circulation of pancreatic cancer patients

(2015) Mark Sausen et al.   Nature Communications

RICTOR Amplification Defines a Novel Subset of Patients with Lung Cancer Who May Benefit from Treatment with mTORC1/2 Inhibitors

(2015) H. Cheng et al.   Cancer Discovery

Next-Generation Sequencing of Stage IV Squamous Cell Lung Cancers Reveals an Association of PI3K Aberrations and Evidence of Clonal Heterogeneity in Patients with Brain Metastases

(2015) P. K. Paik et al.   Cancer Discovery

ShatterProof: operational detection and quantification of chromothripsis

(2014) Shaylan K Govind et al.   BMC BIOINFORMATICS

Therapeutic Priority of the PI3K/AKT/mTOR Pathway in Small Cell Lung Cancers as Revealed by a Comprehensive Genomic Analysis

(2014) Shigeki Umemura et al.   Journal of Thoracic Oncology

Ki-67 Antigen in Lung Neuroendocrine Tumors: Unraveling a Role in Clinical Practice

(2014) Giuseppe Pelosi et al.   Journal of Thoracic Oncology

Frequent mutations in chromatin-remodelling genes in pulmonary carcinoids

(2014) Lynnette Fernandez-Cuesta et al.   Nature Communications

Mechanism of Suppression of Chromosomal Instability by DNA Polymerase POLQ

(2014) Matthew J. Yousefzadeh et al.   PLoS Genetics

Grading the neuroendocrine tumors of the lung: an evidence-based proposal

(2013) G Rindi et al.   ENDOCRINE-RELATED CANCER

MEN1Gene Mutation and Reduced Expression Are Associated With Poor Prognosis in Pulmonary Carcinoids

(2013) Dorian R. A. Swarts et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

DNA Qualification Workflow for Next Generation Sequencing of Histopathological Samples

(2013) Michele Simbolo et al.   PLoS One

Treatment of pulmonary neuroendocrine tumours: State of the art and future developments

(2012) Cesare Gridelli et al.   CANCER TREATMENT REVIEWS

Genomic Landscape of Non-Small Cell Lung Cancer in Smokers and Never-Smokers

(2012) Ramaswamy Govindan et al.   CELL

A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff

(2012) Pablo Cingolani et al.   FLY

Detecting false-positive signals in exome sequencing

(2012) Karin V. Fuentes Fajardo et al.   HUMAN MUTATION

Alteredp16INK4and RB1 Expressions Are Associated with Poor Prognosis in Patients with Nonsmall Cell Lung Cancer

(2012) Weiqiang Zhao et al.   Journal of Oncology

Application of Microfluidic Technology to the BIOMED-2 Protocol for Detection of B-Cell Clonality

(2011) Alberto Zamò et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Integrative genomics viewer

(2011) James T Robinson et al.   NATURE BIOTECHNOLOGY

Exome sequencing identifies a spectrum of mutation frequencies in advanced and lethal prostate cancers

(2011) A. Kumar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Deriving the consequences of genomic variants with the Ensembl API and SNP Effect Predictor

(2010) William McLaren et al.   BIOINFORMATICS

Somatostatin receptor tissue distribution in lung neuroendocrine tumours: a clinicopathologic and immunohistochemical study of 218 'clinically aggressive' cases

(2009) L. Righi et al.   ANNALS OF ONCOLOGY

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

Pulmonary neuroendocrine/carcinoid tumors

(2009) Erin M. Bertino et al.   CANCER

Low-fidelity DNA synthesis by human DNA polymerase theta

(2008) M. E. Arana et al.   NUCLEIC ACIDS RESEARCH