Differential contributions of the proteasome, autophagy, and chaperones to the clearance of arsenite-induced protein aggregates in yeast

High and stable ATP levels prevent aberrant intracellular protein aggregation in yeast

(2022) Masak Takaine et al.   eLife

Genome-wide imaging screen uncovers molecular determinants of arsenite-induced protein aggregation and toxicity

(2021) Stefanie Andersson et al.   JOURNAL OF CELL SCIENCE

Metals associated neurodegeneration in Parkinson’s disease: Insight to physiological, pathological mechanisms and management

(2021) Khadga Raj et al.   NEUROSCIENCE LETTERS

Effects of the Toxic Metals Arsenite and Cadmium on α-Synuclein Aggregation In Vitro and in Cells

(2021) Emma Lorentzon et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Class-specific interactions between Sis1 J-domain protein and Hsp70 chaperone potentiate disaggregation of misfolded proteins

(2021) Hubert Wyszkowski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ubiquitin Ligase Redundancy and Nuclear-Cytoplasmic Localization in Yeast Protein Quality Control

(2021) Carolyn Allain Breckel et al.   Biomolecules

Arsenic Exposure and Compromised Protein Quality Control

(2020) Lok Ming Tam et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Global threat of arsenic in groundwater

(2020) Joel Podgorski et al.   SCIENCE

Chaperone-Mediated Protein Disaggregation Triggers Proteolytic Clearance of Intra-nuclear Protein Inclusions

(2020) Fabian den Brave et al.   Cell Reports

ATP hydrolysis by yeast Hsp104 determines protein aggregate dissolution and size in vivo

(2020) Udhayabhaskar Sathyanarayanan et al.   Nature Communications

The proteostasis network and its decline in ageing

(2019) Mark S. Hipp et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Selective Hsp70-Dependent Docking of Hsp104 to Protein Aggregates Protects the Cell from the Toxicity of the Disaggregase

(2019) Tomasz Chamera et al.   JOURNAL OF MOLECULAR BIOLOGY

A review on arsenic carcinogenesis: Epidemiology, metabolism, genotoxicity and epigenetic changes

(2018) Qing Zhou et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Shaping proteostasis at the cellular, tissue, and organismal level

(2017) Ambre J. Sala et al.   JOURNAL OF CELL BIOLOGY

ATP as a biological hydrotrope

(2017) Avinash Patel et al.   SCIENCE

Failure of RQC machinery causes protein aggregation and proteotoxic stress

(2016) Young-Jun Choe et al.   NATURE

The increasing complexity of the ubiquitin code

(2016) Richard Yau et al.   NATURE CELL BIOLOGY

Proteomic Analysis Identifies Ribosome Reduction as an Effective Proteotoxic Stress Response

(2015) Angel Guerra-Moreno et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Systematic identification of arsenic-binding proteins reveals that hexokinase-2 is inhibited by arsenic

(2015) Hai-nan Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Environmental pollutants as risk factors for neurodegenerative disorders: Alzheimer and Parkinson diseases

(2015) Miguel Chin-Chan et al.   Frontiers in Cellular Neuroscience

Potentiated Hsp104 Variants Antagonize Diverse Proteotoxic Misfolding Events

(2014) Meredith E. Jackrel et al.   CELL

Rapid Glucose Depletion Immobilizes Active Myosin V on Stabilized Actin Cables

(2014) Li Xu et al.   CURRENT BIOLOGY

Opposing roles of Ubp3-dependent deubiquitination regulate replicative life span and heat resistance

(2014) D. Oling et al.   EMBO JOURNAL

Mathematical modelling of arsenic transport, distribution and detoxification processes in yeast

(2014) Soheil Rastgou Talemi et al.   MOLECULAR MICROBIOLOGY

Global analysis of protein aggregation in yeast during physiological conditions and arsenite stress

(2014) S. Ibstedt et al.   Biology Open

PolyQ Proteins Interfere with Nuclear Degradation of Cytosolic Proteins by Sequestering the Sis1p Chaperone

(2013) Sae-Hun Park et al.   CELL

Arsenic Binding to Proteins

(2013) Shengwen Shen et al.   CHEMICAL REVIEWS

The Broad Scope of Health Effects from Chronic Arsenic Exposure: Update on a Worldwide Public Health Problem

(2013) Marisa F. Naujokas et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Cuz1/Ynl155w, a Zinc-dependent Ubiquitin-binding Protein, Protects Cells from Metalloid-induced Proteotoxicity

(2013) John Hanna et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Disruption of Ionic Interactions between the Nucleotide Binding Domain 1 (NBD1) and Middle (M) Domain in Hsp100 Disaggregase Unleashes Toxic Hyperactivity and Partial Independence from Hsp70

(2012) Natalia Lipińska et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular chaperones and stress-inducible protein-sorting factors coordinate the spatiotemporal distribution of protein aggregates

(2012) Liliana Malinovska et al.   MOLECULAR BIOLOGY OF THE CELL

Development of Cysteine-Free Fluorescent Proteins for the Oxidative Environment

(2012) Takahisa Suzuki et al.   PLoS One

Trivalent Arsenic Inhibits the Functions of Chaperonin Complex

(2010) X. Pan et al.   GENETICS

Arsenic(III) Species Inhibit Oxidative Protein Foldingin Vitro†

(2008) Danny Ramadan et al.   BIOCHEMISTRY

Arsenic Trioxide Augments Chk2/p53-mediated Apoptosis by Inhibiting Oncogenic Wip1 Phosphatase

(2008) Akinori Yoda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Insights into the structural dynamics of the Hsp110-Hsp70 interaction reveal the mechanism for nucleotide exchange activity

(2008) C. Andreasson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA