Article
Immunology
Zahra M. Clayborne, Runyu Zou, Stephen E. Gilman, Golam M. Khandaker, Deshayne B. Fell, Ian Colman, Hanan El Marroun
Summary: This study found associations between prenatal maternal stress and children's internalizing and externalizing symptoms, as well as explored the relationship between prenatal maternal stress and maternal inflammation during pregnancy. The results showed that prenatal maternal stress was related to children's internalizing and externalizing symptoms from 3 to 10 years of age. However, there was no evidence that maternal inflammation mediated the associations between prenatal maternal stress and children's symptoms.
BRAIN BEHAVIOR AND IMMUNITY
(2023)
Article
Biochemistry & Molecular Biology
Edward B. Quinn, Chu J. Hsiao, Felicien M. Maisha, Connie J. Mulligan
Summary: Prenatal maternal stress has been found to have negative effects on child health, but the exact mechanisms are not well understood. This study in the Democratic Republic of Congo examined the impact of maternal stress on DNA methylation in mothers and newborns. It was found that different types of trauma, such as sexual trauma and war trauma, were associated with changes in DNA methylation in both mothers and newborns, while chronic stress did not have such an effect.
Article
Psychology, Clinical
Zahra M. Clayborne, Wendy Nilsen, Fartein Ask Torvik, Kristin Gustavson, Mona Bekkhus, Stephen E. Gilman, Golam M. Khandaker, Deshayne B. Fell, Ian Colman
Summary: This study examines the associations between prenatal maternal stress and child mental health outcomes, and the moderating effects of parenting behaviors. The results confirm the associations between prenatal maternal stress and children's mental health, and demonstrate that these associations may be modified by parenting behaviors.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Psychology, Multidisciplinary
Jennifer E. Khoury, Hargun Kaur, Andrea Gonzalez
Summary: The study examined changes in child internalizing and externalizing problems during the pandemic, finding that children experienced significant increases in both during this period. Parenting behavior and parental mental health were associated with changes in child mental health problems.
FRONTIERS IN PSYCHOLOGY
(2021)
Article
Pharmacology & Pharmacy
Rashida S. S. Smith-Webb, Ruby Barnard-Mayers, Martha M. M. Werler, Samantha E. E. Parker
Summary: Acetaminophen, a commonly used medication during pregnancy, has been linked to adverse neurodevelopmental outcomes in childhood, but its associations with outcomes in adolescence are less known.
FRONTIERS IN PHARMACOLOGY
(2023)
Article
Pediatrics
Stacey N. Doan, Anna Beth Burniston, Patricia Smiley, Cindy H. Liu
Summary: The COVID-19 pandemic is associated with behavioral problems in children. However, there is a lack of longitudinal studies with pre-pandemic data, and few studies have examined the family context. This study found that the pandemic had a significant negative impact on children's behavior and maternal mental health.
Article
Environmental Sciences
Nichole Nidey, Katherine Bowers, Lili Ding, Hong Ji, Robert T. Ammerman, Kimberly Yolton, E. Melinda Mahabee-Gittens, Alonzo T. Folger
Summary: This study investigated the effects of in-utero exposure to maternal smoking on DNA methylation of AVPR1a gene in infants. The findings suggest that infants with in-utero exposure to maternal smoking have reduced DNA methylation at AVPR1a CpG sites.
Article
Psychology, Developmental
Nicole Creasey, Roseriet Beijers, Kieran J. O'Donnell, Carolina de Weerth, Marieke S. Tollenaar
Summary: The early caregiving environment has long-term effects on child mental health. This study examined the mediating role of DNA methylation in the glucocorticoid receptor gene (NR3C1) in linking responsive caregiving to improved behavioral outcomes. The results showed that higher maternal sensitivity at 5 weeks predicted lower DNA methylation levels at certain NR3C1 CpG loci, but did not mediate the effect on child internalizing and externalizing behavior. The significance of these findings for child mental health remains unclear.
DEVELOPMENT AND PSYCHOPATHOLOGY
(2023)
Article
Family Studies
Jennifer E. Khoury, Masako Tanaka, Melissa Kimber, Harriet L. MacMillan, Tracie O. Afifi, Michael Boyle, Laura Duncan, Divya Joshi, Katholiki Georgiades, Andrea Gonzalez
Summary: This study found unique associations between specific PCM subtypes and YM subtypes with youth mental health problems. After considering other maltreatment subtypes, the impact of parent emotional abuse on youth internalizing and externalizing problems became nonsignificant. The involvement of multiple informants in youth mental health problems is crucial.
CHILD ABUSE & NEGLECT
(2022)
Article
Clinical Neurology
Lei Yue, Naixue Cui, Zhenzhen Liu, Cunxian Jia, Xianchen Liu
Summary: This study identifies three distinct patterns of sleep problems among adolescents and explores their association with internalizing and externalizing problems. The findings demonstrate the importance of identifying these patterns to effectively target interventions and promote emotional and behavioral health in adolescents.
Article
Psychology, Developmental
Eszter Szekely, Alexander Neumann, Hannah Sallis, Alexia Jolicoeur-Martineau, Frank C. Verhulst, Michael J. Meaney, Rebecca M. Pearson, Robert D. Levitan, James L. Kennedy, John E. Lydon, Meir Steiner, Celia M. T. Greenwood, Henning Tiemeier, Jonathan Evans, Ashley Wazana
Summary: This study found that prenatal maternal general affective symptoms and pregnancy-specific worries can independently have adverse effects on offspring psychopathology, further supporting the need for specific interventions during pregnancy.
JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY
(2021)
Article
Psychology, Developmental
Liliana J. Lengua, Stephanie F. Thompson, Stephanie Gyuri Kim, Maya L. Rosen, Alexandra Rodman, Steven Kasparek, Makeda Mayes, Maureen Zalewski, Andrew Meltzoff, Kate A. McLaughlin
Summary: This study found that adolescent mental health is closely tied to maternal mental health during the COVID-19 pandemic. The study also found that pre-existing family economic context and adolescent symptoms increase the risk for elevations in symptoms of psychopathology.
JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY
(2022)
Article
Genetics & Heredity
Rebekah L. Petroff, Vasantha Padmanabhan, Dana C. Dolinoy, Deborah J. Watkins, Joseph Ciarelli, Diana Haggerty, Douglas M. Ruden, Jaclyn M. Goodrich
Summary: This study investigated the impact of prenatal exposure to phthalates on fetal DNA methylation and found sex-specific alterations in infant DNA methylation.
FRONTIERS IN GENETICS
(2022)
Article
Psychiatry
Livio Provenzi, Marco Villa, Fabiana Mambretti, Andrea Citterio, Serena Grumi, Emanuela Bertazzoli, Giacomo Biasucci, Lidia Decembrino, Barbara Gardella, Roberta Giacchero, Maria Luisa Magnani, Renata Nacinovich, Camilla Pisoni, Federico Prefumo, Simona Orcesi, Barbara Scelsa, Roberto Giorda, Renato Borgatti
Summary: This study suggests that pandemic-related stress may increase the risk of anxiety in mothers, and BDNF epigenetic regulation might play a significant role in this association.
FRONTIERS IN PSYCHIATRY
(2022)
Article
Psychology, Developmental
Lydia Gabriela Speyer, Samuel Neaves, Hildigunnur Anna Hall, Gibran Hemani, Michael Vincent Lombardo, Aja Louise Murray, Bonnie Auyeung, Michelle Luciano
Summary: This study investigated the joint developmental trajectories of internalizing and externalizing problems using parallel process latent class growth analysis, identifying five classes ranging from unaffected to high internalizing and externalizing symptoms. Results showed that affected classes were distinguishable from the unaffected class based on factors such as sex, maternal age, maternal mental health, and child polygenic risk scores. Additionally, phenotypic and polygenic predictors had limited ability to differentiate between different affected classes, suggesting shared risk factors for internalizing and externalizing problems.
JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY
(2022)
Article
Clinical Neurology
Jai Carmichael, Jennie Ponsford, Kate Rachel Gould, Gershon Spitz
Summary: The traditional approaches to measuring depression after traumatic brain injury (TBI) have limitations. This study adopted a symptom-oriented approach and found that post-TBI depression is highly heterogeneous. Different depressive symptoms have distinct associations with personal, injury-related, treatment, and outcome factors.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Xiaoning Sun, Min Chen, Guanghai Wang, Fan Jiang
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Aleksander Kwas
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Josine E. Verhoeven, Laura K. M. Han, Brenda W. J. H. Penninx
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Review
Clinical Neurology
Erin Crowe, Petra K. Staiger, Steven J. Bowe, Imogen Rehm, Richard Moulding, Caitlyn Herrick, David J. Hallford
Summary: This study aimed to integrate the evidence regarding the relationship between emotion regulation difficulties and TTM symptoms, and found that individuals with higher levels of TTM severity appear to exhibit decreased overall emotion regulation abilities and strategies.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Fjolla Berisha, Marjolaine Rivest-Beauregard, Jai Shah, Michelle Lonergan, Alain Brunet
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Yi-Tseng Tsai, Tzu-Jung Chuang, Sriyani Padmalatha Konara Mudiyanselage, Han-Chang Ku, Yi-Lin Wu, Chung-Yi Li, Nai-Ying Ko
Summary: Sleep disturbances are associated with higher suicide rates, and this association is independent of depression. Paying attention to sleep disturbances among PLHIV is crucial when monitoring suicidal ideation.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Junyou Chen, Ingrid D. Lui, Yu Cheng Hsu, Paul S. F. Yip
Summary: Despite rapid social changes in Hong Kong, marriage remains a strong protective factor against suicide for both men and women, particularly among younger individuals. Increasing suicide rates among divorced/separated, never-married, or widowed individuals suggest a need for more psychosocial support.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
A. Perry, K. Gordon-Smith, K. J. S. Lewis, A. Di Florio, N. Craddock, L. Jones, I. Jones
Summary: This study found that the experience of losing at least one night of sleep was associated with an increased risk of postpartum psychosis in women with bipolar disorder. Sleep quality in late pregnancy was not associated with postpartum psychosis, and perinatal sleep disruption was not associated with postpartum depression.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Dear J. Affect Disord, Mark J. Niciu, Robert C. Meisner, Brent R. Carr, Ali A. Farooqui, David Feifel, Adam Kaplin, Paul M. Kim, Christopher D. Schneck, Jennifer L. Vande Voort, Sagar Parikh, E. Jeremy Kendrick
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Tao Wang, Li Yang, Lan Yang, Bao-Peng Liu, Cun-Xian Jia
Summary: This study systematically reviewed the association between psychological pain and suicidality in patients with major depressive disorder (MDD). The results showed that psychological pain was a risk factor for suicidality in MDD patients, especially for those of advancing age. Reducing psychological pain in MDD patients is important for preventing suicidality.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Juan Carlos Hugues, Abel Nogueira-Lopeza, Maeva Flayellea, Cora von Hammersteind, Joel Billieuxa
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Ogechi Cynthia Onyeka, Samuel D. Spencer, Alison Salloum, Katie Jiannetto, Eric A. Storch
Summary: This study examined the relationship among family accommodation (FA), posttraumatic stress symptoms (PTSS), and functional impairment. The results showed that FA was significantly associated with PTSS and functional impairment. Baseline FA partially mediated the relationship between baseline PTSS and functional impairment. Changes in FA from pre- to post-treatment were associated with relevant outcome variables at post-treatment and 12-month follow-up.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Yumeng Shi, Chao Yu
Summary: This study found a negative correlation between the intake of active microbes in the diet and depression.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Qiurui Nie, Yu Shen, Mengqin Luo, Zhiyong Sheng, Rui Zhou, Guangmin Li, Wei Huang, Shenjian Chen
Summary: The study assessed the sleep duration, sleep disorders, and trouble sleeping among adults in the United States from 2005 to 2018, revealing a high prevalence of abnormal sleep durations and increasing rates of sleep disorders and trouble sleeping.
JOURNAL OF AFFECTIVE DISORDERS
(2024)