Gsk-3-Mediated Proteasomal Degradation of ATF4 Is a Proapoptotic Mechanism in Mouse Pancreatic β-Cells

ATF4-mediated transcriptional regulation protects against β-cell loss during endoplasmic reticulum stress in a mouse model

(2021) Keisuke Kitakaze et al.   Molecular Metabolism

CK1δ stimulates ubiquitination‐dependent proteasomal degradation of ATF4 to promote chemoresistance in gastric Cancer

(2021) Lifeng Feng et al.   Clinical and Translational Medicine

Mechanisms, regulation and functions of the unfolded protein response

(2020) Claudio Hetz et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Regulation of cellular immunity by activating transcription factor 4

(2020) Debasmita Mukherjee et al.   IMMUNOLOGY LETTERS

A partnership with the proteasome; the destructive nature of GSK3

(2018) Holly Robertson et al.   BIOCHEMICAL PHARMACOLOGY

The integrated stress response

(2016) Karolina Pakos‐Zebrucka et al.   EMBO REPORTS

Crystal structure of eukaryotic translation initiation factor 2B

(2016) Kazuhiro Kashiwagi et al.   NATURE

Regulation of ER stress-induced autophagy by GSK3β-TIP60-ULK1 pathway

(2016) Tiejian Nie et al.   Cell Death & Disease

Glycogen synthase kinase-3 (GSK3): Regulation, actions, and diseases

(2015) Eleonore Beurel et al.   PHARMACOLOGY & THERAPEUTICS

Involvement of Oxidative Stress–Induced DNA Damage, Endoplasmic Reticulum Stress, and Autophagy Deficits in the Decline of β-Cell Mass in Japanese Type 2 Diabetic Patients

(2014) Hiroki Mizukami et al.   DIABETES CARE

Islet β cell mass in diabetes and how it relates to function, birth, and death

(2013) Gordon C. Weir et al.   Annals of the New York Academy of Sciences

Protein phosphorylation-acetylation cascade connects growth factor deprivation to autophagy

(2012) Shu-Yong Lin et al.   Autophagy

GSK3-TIP60-ULK1 Signaling Pathway Links Growth Factor Deprivation to Autophagy

(2012) S.-Y. Lin et al.   SCIENCE

Wolfram syndrome 1 gene (WFS1) product localizes to secretory granules and determines granule acidification in pancreatic  -cells

(2011) M. Hatanaka et al.   HUMAN MOLECULAR GENETICS

Type 2 diabetes across generations: from pathophysiology to prevention and management

(2011) Christopher J Nolan et al.   LANCET

Frat Is a Phosphatidylinositol 3-Kinase/Akt-Regulated Determinant of Glycogen Synthase Kinase 3  Subcellular Localization in Pluripotent Cells

(2011) M. Bechard et al.   MOLECULAR AND CELLULAR BIOLOGY

Glucose and Fatty Acids Synergize to Promote B-Cell Apoptosis through Activation of Glycogen Synthase Kinase 3β Independent of JNK Activation

(2011) Katsuya Tanabe et al.   PLoS One

Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease

(2010) Gökhan S. Hotamisligil   CELL

Conditional ablation of Gsk-3β in islet beta cells results in expanded mass and resistance to fat feeding-induced diabetes in mice

(2010) Y. Liu et al.   DIABETOLOGIA

ATF4-Mediated Induction of 4E-BP1 Contributes to Pancreatic β Cell Survival under Endoplasmic Reticulum Stress

(2008) Suguru Yamaguchi et al.   Cell Metabolism

The Role for Endoplasmic Reticulum Stress in Diabetes Mellitus

(2008) Décio L. Eizirik et al.   ENDOCRINE REVIEWS

Glucolipotoxicity: Fuel Excess and β-Cell Dysfunction

(2008) Vincent Poitout et al.   ENDOCRINE REVIEWS

Genetic Deficiency of Glycogen Synthase Kinase-3β Corrects Diabetes in Mouse Models of Insulin Resistance

(2008) Katsuya Tanabe et al.   PLOS BIOLOGY