Anti-Obesity Effects of Metformin: A Scoping Review Evaluating the Feasibility of Brown Adipose Tissue as a Therapeutic Target
出版年份 2023 全文链接
标题
Anti-Obesity Effects of Metformin: A Scoping Review Evaluating the Feasibility of Brown Adipose Tissue as a Therapeutic Target
作者
关键词
-
出版物
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 24, Issue 3, Pages 2227
出版商
MDPI AG
发表日期
2023-01-23
DOI
10.3390/ijms24032227
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- FGF21: A Novel Regulator of Glucose and Lipid Metabolism and Whole-Body Energy Balance
- (2022) Ewa Szczepańska et al. HORMONE AND METABOLIC RESEARCH
- Impact of physical exercise and caloric restriction in patients with type 2 diabetes: Skeletal muscle insulin resistance and mitochondrial dysfunction as ideal therapeutic targets
- (2022) Sinenhlanhla X.H. Mthembu et al. LIFE SCIENCES
- Pharmacological treatment with FGF21 strongly improves plasma cholesterol metabolism to reduce atherosclerosis
- (2021) Cong Liu et al. CARDIOVASCULAR RESEARCH
- Multifaceted Mechanisms of Action of Metformin Which Have Been Unraveled One after Another in the Long History
- (2021) Hideaki Kaneto et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Efficacy and Safety of Metformin for Obesity: A Systematic Review
- (2021) Reem Masarwa et al. PEDIATRICS
- The Antiobesity Effect of GLP-1 Receptor Agonists Alone or in Combination with Metformin in Overweight /Obese Women with Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis
- (2021) Xiaorui Lyu et al. International Journal of Endocrinology
- The aberrant expression of CD69 on peripheral T-helper cells in diet-induced inflammation is ameliorated by low-dose aspirin and metformin treatment
- (2021) Tawanda Maurice Nyambuya et al. CELLULAR IMMUNOLOGY
- Brown and beige adipose tissue regulate systemic metabolism through a metabolite interorgan signaling axis
- (2021) Anna Whitehead et al. Nature Communications
- Diet-induced obesity in animal models: points to consider and influence on metabolic markers
- (2021) Mariana de Moura e Dias et al. Diabetology & Metabolic Syndrome
- Metformin Strongly Affects Gut Microbiome Composition in High-Fat Diet-Induced Type 2 Diabetes Mouse Model of Both Sexes
- (2021) Laila Silamiķele et al. Frontiers in Endocrinology
- Signaling Pathways Regulating Thermogenesis
- (2021) Chihiro Tabuchi et al. Frontiers in Endocrinology
- The Role of AMPK Signaling in Brown Adipose Tissue Activation
- (2021) Jamie I. van der Vaart et al. Cells
- Experimental models of lipid overload and their relevance in understanding skeletal muscle insulin resistance and pathological changes in mitochondrial oxidative capacity
- (2021) Sinenhlanhla X.H. Mthembu et al. BIOCHIMIE
- Therapeutic Perspectives of Thermogenic Adipocytes in Obesity and Related Complications
- (2021) Chih-Hao Wang et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Perilipin 5 links mitochondrial uncoupled respiration in brown fat to healthy white fat remodeling and systemic glucose tolerance
- (2021) Violeta I. Gallardo-Montejano et al. Nature Communications
- Metformin Therapy Effects on the Expression of Sodium-Glucose Cotransporter 2, Leptin, and SIRT6 Levels in Pericoronary Fat Excised from Pre-Diabetic Patients with Acute Myocardial Infarction
- (2021) Celestino Sardu et al. Biomedicines
- Protective Effects of Individual and Combined Low Dose Beta-Carotene and Metformin Treatments against High-Fat Diet-Induced Responses in Mice
- (2021) Bojan Stojnić et al. Nutrients
- Metformin reduces macrophage HIF1α-dependent proinflammatory signaling to restore brown adipocyte function in vitro
- (2021) Nuria Pescador et al. Redox Biology
- Effects of Metformin in Heart Failure: From Pathophysiological Rationale to Clinical Evidence
- (2021) Teresa Salvatore et al. Biomolecules
- Physical Exercise Potentially Targets Epicardial Adipose Tissue to Reduce Cardiovascular Disease Risk in Patients with Metabolic Diseases: Oxidative Stress and Inflammation Emerge as Major Therapeutic Targets
- (2021) Thembeka A. Nyawo et al. Antioxidants
- Fibroblast Growth Factor-21, Leptin, and Adiponectin Responses to Acute Cold-Induced Brown Adipose Tissue Activation
- (2020) Lijuan Sun et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Dietary polyphenols turn fat “brown”: A narrative review of the possible mechanisms
- (2020) Jiamiao Hu et al. TRENDS IN FOOD SCIENCE & TECHNOLOGY
- Metformin Therapy Reduces Obesity Indices in Children and Adolescents: A Systematic Review and Meta-Analysis of Randomized Clinical Trials
- (2020) Alireza Sadeghi et al. Childhood Obesity
- Effects of Short Term Metformin Treatment on Brown Adipose Tissue Activity and Plasma Irisin Levels in Women with Polycystic Ovary Syndrome: A Randomized Controlled Trial
- (2020) Flávia R. Oliveira et al. HORMONE AND METABOLIC RESEARCH
- The Metformin Mechanism on Gluconeogenesis and AMPK Activation: The Metabolite Perspective
- (2020) Loranne Agius et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The impact of metformin and aspirin on T-cell mediated inflammation: A systematic review of in vitro and in vivo findings
- (2020) Tawanda Maurice Nyambuya et al. LIFE SCIENCES
- Exploring the Comparative Efficacy of Metformin and Resveratrol in the Management of Diabetes-Associated Complications: A Systematic Review of Preclinical Studies
- (2020) Phiwayinkosi V. Dludla et al. Nutrients
- Metformin and Its Benefits for Various Diseases
- (2020) Ziquan Lv et al. Frontiers in Endocrinology
- Stimulation of brown adipose tissue by polyphenols in extra virgin olive oil
- (2020) L. Melguizo Rodríguez et al. CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
- Isoorientin: A dietary flavone with the potential to ameliorate diverse metabolic complications
- (2020) Khanyisani Ziqubu et al. PHARMACOLOGICAL RESEARCH
- Cellular and Molecular Mechanisms of Metformin Action
- (2020) Traci E LaMoia et al. ENDOCRINE REVIEWS
- Induction of Adipose Tissue Browning as a Strategy to Combat Obesity
- (2020) Alina Kuryłowicz et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Adipokines as a therapeutic target by metformin to improve metabolic function: A systematic review of randomized controlled trials
- (2020) Phiwayinkosi V. Dludla et al. PHARMACOLOGICAL RESEARCH
- Basal and cold-induced fatty acid uptake of human brown adipose tissue is impaired in obesity
- (2020) T. J. Saari et al. Scientific Reports
- Substrate Utilization by Brown Adipose Tissue: What’s Hot and What’s Not?
- (2020) Ben T. McNeill et al. Frontiers in Endocrinology
- Long-term trends in the prescription of antidiabetic drugs: real-world evidence from the Diabetes Registry Tyrol 2012–2018
- (2020) Clemens Engler et al. BMJ Open Diabetes Research & Care
- Effect of metformin on stem cells: Molecular mechanism and clinical prospect
- (2020) Lin-Li Jiang et al. World Journal of Stem Cells
- Mechanisms of Impaired Brown Adipose Tissue Recruitment in Obesity
- (2019) Martín Alcalá et al. Frontiers in Physiology
- AMP-activated protein kinase: the current landscape for drug development
- (2019) Gregory R. Steinberg et al. NATURE REVIEWS DRUG DISCOVERY
- Aspalathin-Enriched Green Rooibos Extract Reduces Hepatic Insulin Resistance by Modulating PI3K/AKT and AMPK Pathways
- (2019) Sithandiwe Mazibuko-Mbeje et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Metformin enhances mitochondrial biogenesis and thermogenesis in brown adipocytes of mice
- (2019) Iara Karise et al. BIOMEDICINE & PHARMACOTHERAPY
- FGF21 as Modulator of Metabolism in Health and Disease
- (2019) Caterina Tezze et al. Frontiers in Physiology
- Phenformin as an Anticancer Agent: Challenges and Prospects
- (2019) Rubiño et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Flavonoids as inducers of white adipose tissue browning and thermogenesis: signalling pathways and molecular triggers
- (2019) Xuejun Zhang et al. Nutrition & Metabolism
- Amelioration of metabolic syndrome by metformin associates with reduced indices of low-grade inflammation independently of the gut microbiota
- (2019) Aneseh Adeshirlarijaney et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- The beneficial effects of N-acetyl cysteine (NAC) against obesity associated complications: A systematic review of pre-clinical studies
- (2019) Phiwayinkosi V. Dludla et al. PHARMACOLOGICAL RESEARCH
- Mechanisms linking adipose tissue inflammation to cardiac hypertrophy and fibrosis
- (2019) Sarah R. Anthony et al. CLINICAL SCIENCE
- Effects of metformin on metabolism of white and brown adipose tissue in obese C57BL/6J mice
- (2019) Tao Yuan et al. Diabetology & Metabolic Syndrome
- Browning of white adipose tissue induced by the ß3 agonist CL-316,243 after local and systemic treatment - PK-PD relationship
- (2018) Wojciech Danysz et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Regulation of Human Adipose Tissue Activation, Gallbladder Size, and Bile Acid Metabolism by a β3-Adrenergic Receptor Agonist
- (2018) Alison S. Baskin et al. DIABETES
- Metformin targets brown adipose tissue in vivo and reduces oxygen consumption in vitro
- (2018) Peter Breining et al. DIABETES OBESITY & METABOLISM
- Exercise-induced ‘browning’ of adipose tissues
- (2018) Peter Aldiss et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- The possible antidiabetic effects of vitamin D receptors agonist in rat model of type 2 diabetes
- (2018) Wafaa M. Abdel-Rehim et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Animal models of obesity and diabetes mellitus
- (2018) Maximilian Kleinert et al. Nature Reviews Endocrinology
- The epidemiology of obesity
- (2018) Yu Chung Chooi et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Uncoupling proteins as a therapeutic target to protect the diabetic heart
- (2018) Phiwayinkosi V. Dludla et al. PHARMACOLOGICAL RESEARCH
- Pleiotropic effects of metformin: Shaping the microbiome to manage type 2 diabetes and postpone ageing
- (2018) Francesco Prattichizzo et al. AGEING RESEARCH REVIEWS
- The Effects of Resveratrol, Metformin, Cold and Strength Training on the Level of Perilipin 5 in the Heart, Skeletal Muscle and Brown Adipose Tissues in Mouse
- (2018) Fadaei Mehdi et al. CELL BIOCHEMISTRY AND BIOPHYSICS
- Metformin induces weight loss associated with gut microbiota alteration in non-diabetic obese women: a randomized double-blind clinical trial
- (2018) Hanieh-Sadat Ejtahed et al. EUROPEAN JOURNAL OF ENDOCRINOLOGY
- Dietary polyphenols and their roles in fat browning
- (2018) Allwin Jennifa Silvester et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- Metformin suppresses adipogenesis through both AMP-activated protein kinase (AMPK)-dependent and AMPK-independent mechanisms
- (2017) Suet Ching Chen et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Metformin for Obesity in Prepubertal and Pubertal Children: A Randomized Controlled Trial
- (2017) Belén Pastor-Villaescusa et al. PEDIATRICS
- AMPK as a Therapeutic Target for Treating Metabolic Diseases
- (2017) Emily A. Day et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Beneficial effects of metformin on energy metabolism and visceral fat volume through a possible mechanism of fatty acid oxidation in human subjects and rats
- (2017) Ichiro Tokubuchi et al. PLoS One
- AMPK/α-Ketoglutarate Axis Dynamically Mediates DNA Demethylation in the Prdm16 Promoter and Brown Adipogenesis
- (2016) Qiyuan Yang et al. Cell Metabolism
- Increased Energy Expenditure,Ucp1Expression, and Resistance to Diet-induced Obesity in Mice Lacking Nuclear Factor-Erythroid-2-related Transcription Factor-2 (Nrf2)
- (2016) Kevin Schneider et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Metformin Prevents Fatty Liver and Improves Balance of White/Brown Adipose in an Obesity Mouse Model by Inducing FGF21
- (2016) Eun Kyung Kim et al. MEDIATORS OF INFLAMMATION
- Metabolic syndrome update
- (2016) Scott M. Grundy TRENDS IN CARDIOVASCULAR MEDICINE
- Maternal high-fat diet during lactation impairs thermogenic function of brown adipose tissue in offspring mice
- (2016) Xingwei Liang et al. Scientific Reports
- Activation of Human Brown Adipose Tissue by a β3-Adrenergic Receptor Agonist
- (2015) Aaron M. Cypess et al. Cell Metabolism
- Resveratrol induces brown-like adipocyte formation in white fat through activation of AMP-activated protein kinase (AMPK) α1
- (2015) S Wang et al. INTERNATIONAL JOURNAL OF OBESITY
- Irisin and FGF21 Are Cold-Induced Endocrine Activators of Brown Fat Function in Humans
- (2014) Paul Lee et al. Cell Metabolism
- Effects of lifestyle modification and metformin on irisin and FGF21 among HIV-infected subjects with the metabolic syndrome
- (2014) Suman Srinivasa et al. CLINICAL ENDOCRINOLOGY
- Obesity and Its Metabolic Complications: The Role of Adipokines and the Relationship between Obesity, Inflammation, Insulin Resistance, Dyslipidemia and Nonalcoholic Fatty Liver Disease
- (2014) Un Jung et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Metformin and Berberine Prevent Olanzapine-Induced Weight Gain in Rats
- (2014) Yueshan Hu et al. PLoS One
- Adipose tissue changes in obesity and the impact on metabolic function
- (2014) Susan Sam et al. Translational Research
- Brown fat fuel utilization and thermogenesis
- (2014) Kristy L. Townsend et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Metformin Lowers Plasma Triglycerides by Promoting VLDL-Triglyceride Clearance by Brown Adipose Tissue in Mice
- (2013) J. J. Geerling et al. DIABETES
- Brown adipose tissue in humans: Therapeutic potential to combat obesity
- (2013) Andrew L. Carey et al. PHARMACOLOGY & THERAPEUTICS
- Acute Exercise Induces FGF21 Expression in Mice and in Healthy Humans
- (2013) Kook Hwan Kim et al. PLoS One
- Pharmacological and nutritional agents promoting browning of white adipose tissue
- (2012) M. Luisa Bonet et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Brown adipose tissue oxidative metabolism contributes to energy expenditure during acute cold exposure in humans
- (2012) Véronique Ouellet et al. JOURNAL OF CLINICAL INVESTIGATION
- Biology of Obesity: Lessons from Animal Models of Obesity
- (2011) Keizo Kanasaki et al. JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY
- Brown versus White Adipose Tissue: A Mini-Review
- (2010) Christoph H. Saely et al. GERONTOLOGY
- AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
- (2009) Carles Cantó et al. NATURE
- Functional Brown Adipose Tissue in Healthy Adults
- (2009) Kirsi A. Virtanen et al. NEW ENGLAND JOURNAL OF MEDICINE
- Cold-Activated Brown Adipose Tissue in Healthy Men
- (2009) Wouter D. van Marken Lichtenbelt et al. NEW ENGLAND JOURNAL OF MEDICINE
- Identification and Importance of Brown Adipose Tissue in Adult Humans
- (2009) Aaron M. Cypess et al. NEW ENGLAND JOURNAL OF MEDICINE
- Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement
- (2009) David Moher et al. PLOS MEDICINE
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now