期刊
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
卷 226, 期 -, 页码 410-422出版社
ELSEVIER
DOI: 10.1016/j.ijbiomac.2022.12.056
关键词
Chitosan; Electrospun fiber; Composites; Medical application
This paper reviews the chemistry of chitosan, the basic principles and influence of electrospinning technology, the blending of chitosan with various polymer materials, the blending of chitosan with inorganic substances for electrospinning, and the application of chitosan electrospinning nanofibers in the medical field and its mechanism in clinical application. It aims to provide reference for further study of electrospinning technology in the field of medical and health.
Chitosan is a kind of polysaccharide cationic polymer, which has excellent biocompatibility, biodegradability and biological activity. In recent years, chitosan has been widely used as medical materials because of its non -toxicity, non-immunogenicity and rich sources. This paper reviews chitosan chemistry, the basic principles and influence of electrospinning technology, the blending of chitosan with polyethylene oxide, polyvinyl alcohol, polycaprolactone, polylactic acid, protein, polysaccharide and other polymer materials, the blending of chitosan with oxides, metals, carbon-based and other inorganic substances for electrospinning, the application of chitosan electrospinning nanofibers in medical field and its mechanism in clinical application. In order to provide reference for the in-depth study of electrospinning technology in the field of medical and health.
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