☆ 4.5 Article

Clinical Profile and Outcome of Neonates with Elizabethkingia Sepsis

INDIAN JOURNAL OF PEDIATRICS (2023)

期刊

INDIAN JOURNAL OF PEDIATRICS

卷 90, 期 6, 页码 612-614

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SPRINGER INDIA

DOI: 10.1007/s12098-022-04467-8

关键词

Elizabethkingia; Neonatal sepsis; Outbreak; Antibiotic resistance

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Pediatrics

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This case series from a tertiary care hospital in South India describes the clinical profile and outcome of 92 neonates with culture-positive Elizabethkingia sepsis. Elizabethkingia sepsis predominantly affected preterm neonates, with common clinical features including respiratory distress, apnea, and poor feeding. Meningitis was noted in 68% of cases, and the mortality rate was 12%. Antimicrobial susceptibility testing showed susceptibility of Elizabethkingia to minocycline and levofloxacin.

Elizabethkingia, an emerging nosocomial pathogen is a gram-negative bacillus causing NICU outbreaks. This case series from a tertiary care hospital, South India describes the clinical profile and outcome of 92 neonates with culture-positive elizabethkingia sepsis over a period of 2 y. Elizabethkingia sepsis predominantly affected preterm neonates and the common clinical features were respiratory distress, apnea, and poor feeding. Meningitis was noted in 68% and mortality was 12%. Antimicrobial susceptibility testing showed that elizabethkingia was susceptible to minocycline and levofloxacin.

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