Article
Public, Environmental & Occupational Health
Hui Liu, Zhenmei Zhang, Yan Zhang
Summary: The study provides insight into the association between trajectories of marital quality and cognitive functioning among older adults, with a focus on gender differences. Initial positive marital quality correlated with better initial cognition in older adults, while negative marital quality correlated with worse cognition. An increase in positive marital quality was associated with a slower rate of cognitive decline in men, emphasizing the importance of maintaining a good marital relationship for cognitive health in later life.
SOCIAL SCIENCE & MEDICINE
(2021)
Article
Geriatrics & Gerontology
Xianwen Shang, David Scott, Roseanne Kimberley Chan, Lei Zhang, Mingguang He
Summary: This study found an independent association between pulmonary function and cognitive function in older adults, with both declining significantly with age. Higher baseline pulmonary function was associated with a slower rate of cognitive decline, and this positive association was stronger in women, lower-educated individuals, or never smokers.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2021)
Article
Public, Environmental & Occupational Health
Yi-Cheng Lin, Chih-Ping Chung, Pei-Lin Lee, Kun-Hsien Chou, Li-Hung Chang, Szu-Ying Lin, Yi-Jung Lee, Ching-Po Lin, Pei-Ning Wang
Summary: The coexistence of physical and cognitive impairments in older adults can predict incident disability, dementia, and mortality. This study investigated the natural course and prevalence of these impairments and found that skeletal muscle mass/function and memory function are crucial factors associated with the progression or reversal of functional impairments.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Psychology, Multidisciplinary
Xiao Wei, Heng Liu, Li Yang, Zihan Gao, Jinke Kuang, Kexin Zhou, Mengfan Xu
Summary: This study examined the bidirectional relationship between physical function and cognition, and found that lower physical function at baseline was associated with cognitive decline, while cognitive decline over time also affected physical function deterioration.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Psychology, Clinical
Yu-Hung Chang, I-Chien Wu, Chao A. Hsiung
Summary: The study found that older adults with higher reading frequencies, especially those reading at least once a week, were less likely to experience cognitive decline, and the protective effect of reading on cognitive function was observed across all levels of education.
INTERNATIONAL PSYCHOGERIATRICS
(2021)
Article
Psychology, Clinical
Bin Yu, Andrew Steptoe, Yongjie Chen, Xiaohua Jia
Summary: Loneliness was significantly associated with cognitive decline at follow-up, but this association became insignificant after controlling for additional confounding variables. On the other hand, social isolation was significantly associated with decreases in cognitive function measures at follow-up, independent of loneliness and other confounding variables. These findings expand our understanding of the relationships between social relationships and cognitive function in non-Western populations.
PSYCHOLOGICAL MEDICINE
(2021)
Article
Psychology, Clinical
Bin Yu, Andrew Steptoe, Yongjie Chen, Xiaohua Jia
Summary: Loneliness was found to be significantly associated with cognitive decline, but the relationship between social isolation and cognitive function decline in Chinese older adults was independent of loneliness even after controlling for confounding variables. These findings provide insights into the links between social relationships and cognitive function in non-Western populations.
PSYCHOLOGICAL MEDICINE
(2021)
Article
Neurosciences
Fabrizio Sanna, Francesco Loy, Raffaella Piras, Alan Moat, Carla Masala
Summary: The study found that olfactory, gustatory, and cognitive functions decline with age, but depression level does not significantly differ across age ranges. Depression level is associated with sex, odor identification impairment, and decreased attention and language skills.
FRONTIERS IN NEUROSCIENCE
(2021)
Article
Health Care Sciences & Services
Guangming Li, Kunmei Li
Summary: This study explores the turning point of cognitive decline in Chinese older adults, which occurs between the ages of 68 and 70. Factors such as residence, education level, smoking, drinking, exercise, leisure activities, social activities, Activities of Daily Living (ADL), and Instrumental Activities for Daily Living (IADL) were found to influence cognitive function. Exercise and ADL were identified as the main protective factors, while smoking and drinking were the main risk factors.
Article
Endocrinology & Metabolism
Earn H. Gan, Carol Jagger, Mohammad E. Yadegarfar, Rachel Duncan, Simon H. Pearce
Summary: In 85-year-old individuals, declining serum TSH is associated with reductions in free thyroid hormones over time and is a biomarker for cognitive impairment in later life.
Article
Pharmacology & Pharmacy
Frank Moriarty, George M. Savva, Carlota M. Grossi, Kathleen Bennett, Chris Fox, Ian Maidment, Yoon K. Loke, Nicholas Steel, Rose Anne Kenny, Kathryn Richardson
Summary: This study aimed to estimate the association between patterns of anticholinergic, benzodiazepine, and Z-drug medication use and change in cognitive function in middle-aged and older adults. The results showed that, except for new use of anticholinergic medications, no other findings supported a risk of cognitive decline over 2-year periods in this cohort. Patients and prescribers should carefully consider the potential risks and benefits of commencing anticholinergic medications.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
(2021)
Article
Public, Environmental & Occupational Health
Sakura Kiuchi, Taro Kusama, Kemmyo Sugiyama, Takafumi Yamamoto, Upul Cooray, Tatsuo Yamamoto, Katsunori Kondo, Ken Osaka, Jun Aida
Summary: The study found an association between poor oral health and subjective cognitive complaints, suggesting that maintaining good oral health is crucial for preventing cognitive decline and reducing the risk of future dementia.
JOURNAL OF EPIDEMIOLOGY
(2022)
Article
Geriatrics & Gerontology
Carolina N. Y. Ling, Jacobijn Gussekloo, Stella Trompet, Carel G. M. Meskers, Andrea B. Maier
Summary: This study investigated the clinical variables associated with handgrip strength and its change over a 4-year period in an oldest old cohort from the Leiden 85-plus Study. It found that body height, weight, and functional performance were positively associated with handgrip strength, and that men experienced a greater decline in handgrip strength compared to women.
AGING CLINICAL AND EXPERIMENTAL RESEARCH
(2021)
Article
Clinical Neurology
Sara Mondini, Veronica Pucci, Sonia Montemurro, Raffaella Ida Rumiati
Summary: This study highlights the importance of education and occupation in predicting cognitive performance in older adults, with higher levels of education and occupation associated with better resistance to cognitive decline. Cognitive reserve plays a crucial role in predicting performance across different levels of cognitive ability.
EUROPEAN JOURNAL OF NEUROLOGY
(2022)
Article
Clinical Neurology
Tingting Liu, Changwei Li, Ruiyuan Zhang, Eugenia Flores Millender, Hongyu Miao, Michael Ormsbee, Jinzhen Guo, Adrianna Westbrook, Yang Pan, Jing Wang, Tanika N. Kelly
Summary: The study found that the polygenic score was associated with cognition changes in both White and Black participants, explaining varying degrees of variance. In diabetes patients, physical activity was able to offset genetic risk and slow down cognitive decline.
ALZHEIMERS RESEARCH & THERAPY
(2023)