Article
Chemistry, Analytical
Haixia Hu, Jiangtao Hu, Kang Xue, Hong Zhou, Xiao Yang, Lijun Wang, Xianggui Chen
Summary: In this study, Fe3O4@Cu@PCPy YSNs nanozymes were synthesized and showed three times higher peroxidase-like activity compared to Fe3O4 nanozymes. A colorimetric aptasensor was developed by designing flower-shaped Apt-CS conjugates on the surface of Fe3O4@Cu@PCPy YSNs, which effectively inhibited their catalytic activity. The aptasensor successfully detected Salmonella Typhimurium in a linear range of 3 to 3 x 106 CFU/mL, with a detection limit of 1 CFU/mL. The feasibility of this aptasensor was further validated by analyzing actual food samples, demonstrating its huge potential for Salmonella Typhimurium detection.
ANALYTICA CHIMICA ACTA
(2023)
Article
Chemistry, Applied
Lifeng Lu, Runzhong Yu, Liyuan Zhang
Summary: A simple and low-cost smartphone-assisted assay was developed for measuring aflatoxin B1 in miscellaneous beans. The assay utilized a modified QuEChERS method with aptamers and gold nanoparticles as recognition elements and indicators, respectively. The assay showed good sensitivity and specificity, with a linear range of 0.2-8.0 ng/g and a detection limit of 0.08 ng/g. The recovery rate of aflatoxin B1 in bean samples ranged from 87.18% to 110.24%. The entire process took only 15 minutes. This colorimetric aptamer sensor can be used for quick aflatoxin B1 detection in beans.
Article
Biochemistry & Molecular Biology
Pengfei Ma, Hualin Guo, Hua Ye, Yin Zhang, Zhouping Wang
Summary: In this study, the recognition mechanism between the truncated DNA aptamer and AFB1 was investigated. It was found that the binding of aptamer to AFB1 was an exothermic process and the conformation of aptamer changed during recognition. The loop bases in the secondary structure of aptamer formed a specific binding pocket to recognize AFB1, with Van der Waals and electrostatic interactions as the main driving forces. Based on the structural investigation, a CRISPR/Cas12a-Exo III aptasensor for AFB1 detection was designed, which showed improved sensitivity through target recycling. This work provides a theoretical foundation for the design of AFB1 aptasensors and suggests new ideas for CRISPR/Cas12a-based aptasensor development.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Engineering, Environmental
Wenjun Ma, Peng He, Tianyi Wang, Jian Xu, Xiaoyun Liu, Qixin Zhuang, Zhong-Kai Cui, Shaoliang Lin
Summary: The paper describes the fabrication and performance of a double-cavity yolk-shell hollow Fe3O4@C microwave absorber, which exhibits outstanding electromagnetic wave absorbing properties due to its unique structure and composition.
CHEMICAL ENGINEERING JOURNAL
(2021)
Article
Chemistry, Inorganic & Nuclear
Zichang Shi, Shan Qing, Zhumei Luo, Yiqin Liu, Jiachen Li
Summary: Fe3O4@C yolk-shell nanoparticles were synthesized through a one-pot solvothermal method and dispersed in deionized water to prepare four different concentrations of water-based Fe3O4@C nanofluids. The average particle size of Fe3O4@C nanoparticles was in the range of 82-84 nm with stable yolk-shell structure and large specific surface area. The stability of Fe3O4@C nanofluids was investigated, showing good stability with maximum zeta potential values at pH 8-9. The thermal properties of Fe3O4@C nanofluids were studied, and they exhibited excellent thermal stability with increased thermal conductivity at higher temperatures and nanoparticle concentrations. The magnetic responsiveness of Fe3O4@C nanofluid was characterized, indicating increased magnetic properties with higher concentrations.
INORGANIC CHEMISTRY COMMUNICATIONS
(2023)
Article
Chemistry, Physical
Xinlu Zheng, Weiwei Zhang, Jinlong Zhang, Lingzhi Wang
Summary: The yolk-shell Fe3O4@void@CeO2 exhibited high SERS sensitivity with an enhanced factor of 1.1 x 10(4) using methylene blue as the analyte model. The enhanced light-scattering ability of the YS structure and improved molecule adsorption benefitting from the more exposed surface played vital roles in the high SERS activity. Additionally, the composite could be conveniently recycled through magnetic separation and light irradiation due to the photocatalytic degradation of MB molecules by CeO2.
APPLIED SURFACE SCIENCE
(2021)
Article
Chemistry, Analytical
Ruipeng Chen, Yunfeng Sun, Bingyang Huo, Zefeng Mao, Xiaojuan Wang, Shiyu Li, Ran Lu, Shuang Li, Jun Liang, Zhixian Gao
Summary: A universal surface-enhanced Raman scattering (SERS) aptasensor was developed for the detection of Zearalenone (ZEN) with a linear detection range from 0.005 to 500 ng mL(-1) and a detection limit of 0.001 ng mL(-1). The sensor showed excellent performance for analytical applications with real-world samples.
ANALYTICA CHIMICA ACTA
(2021)
Article
Engineering, Chemical
Ruixia Yang, Qiaohong Peng, Bing Yu, Youqing Shen, Hailin Cong
Summary: The yolk-shell Fe3O4@MOF-5 nanocomposites exhibited excellent catalytic performance, high specific surface area, superparamagnetic behavior, and remarkable stability in pollutant solutions.
SEPARATION AND PURIFICATION TECHNOLOGY
(2021)
Article
Engineering, Biomedical
Huan Liang, Jingru Guo, Yiyue Shi, Guizhen Zhao, Shouheng Sun, Xiaolian Sun
Summary: A new porous yolk shell nanostructure, PYSNPs, has been reported to stabilize Fe(0) in normal physiological conditions and control its release in the tumor microenvironment for enhanced cancer therapy. These PYSNPs exhibit superior tumor inhibition and can effectively suppress tumor growth in vivo with minimal side effects. Additionally, the disintegration of PYSNPs in the acidic tumor microenvironment can lead to significant changes in MRI signals for contrast-enhanced diagnosis.
Article
Multidisciplinary Sciences
Zhenzhen Li, Jianbang Wang, Itamar Willner
Summary: This study introduces a biomimetic concept to design transient dynamic transcription machineries, allowing gated and cascaded temporal transcription processes. By engineering reaction modules and inhibitors, transient gated and cascaded transcription processes are achieved, leading to the synthesis of transient operating ribozymes.
Article
Biochemistry & Molecular Biology
Haina Tian, Ruifeng Zhang, Jiaqi Li, Cailin Huang, Wen Sun, Zhenqing Hou, Peiyuan Wang
Summary: In this study, a novel Fe3O4 yolk-shell mesoporous carbon nanocarrier was developed, which showed excellent cell membrane adsorption and cellular uptake properties, and enabled precise tumor diagnosis. After drug loading, the nanoparticle exhibited superior tumor cell ablation capability under NIR laser irradiation. This work provides a solid foundation for the diagnosis and therapy of solid tumors.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Chemistry, Physical
Jong-Hwan Park, Sangmin Lee, Jae Chul Ro, Su-Jeong Suh
Summary: The study successfully synthesized yolk-shell Fe-Fe3O4@C nanoparticles, which exhibited excellent microwave absorption performance with optimized parameters including reflection loss, effective bandwidth, and thickness.
APPLIED SURFACE SCIENCE
(2022)
Article
Chemistry, Physical
Ganyin Yuan, Jia Sun, Xiaohuan Sun, Jun Hu, Jie Han, Rong Guo
Summary: Dumbbell-like Au-Fe3O4 nanoparticles encapsulated in N-doped carbon shell were successfully synthesized and demonstrated high stability and enhanced activity in reducing 4-nitrophenol and achieving a 100% yield in benzhydrol oxidation reaction. The nanocatalysts also showed superior recyclability, laying the foundation for practical applications. The elaborate design of this work may lead to the discovery of novel nanocatalysts with superior catalytic performance.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2021)
Article
Chemistry, Multidisciplinary
Ying Li, Lu-Lu Jiang, Ya-Xian Qiao, Dong Wan, Yan-Feng Huang
Summary: The high porosity and versatile structures of metal-organic frameworks (MOFs) have drawn broad attention as new theranostic platforms. Encapsulating functional nanoparticles within MOFs can further develop biomedical applications in drug delivery and bioimaging. Designed yolk-shell magnetic composites show high drug loading capacity, pH-responsive release characteristics, good biocompatibility, and strong MR imaging contrast enhancement.
NEW JOURNAL OF CHEMISTRY
(2021)
Article
Chemistry, Applied
Xilin Dou, Gan Wu, Zhaoyang Ding, Jing Xie
Summary: A ratiometric fluorescence NMOFs-Aptasensor was developed using Cy3-modified aptamer and zirconium-based nanoscale metal-organic frameworks (NMOFs). The NMOFs served as energy donors while the Cy3 labeled aptamer served as an acceptor. The NMOFs-Aptasensor showed great detection performance for AFB1 with a LOD of 0.08 ng mL(-1), and was successfully applied for AFB1 detection in real samples.
Article
Chemistry, Applied
M. Graca Dias, Elsa Vasco, Francisco Ravasco, Lufsa Oliveira
Summary: This study estimated the vitamin D intake of "adults" and "elderly" populations in Portugal using the TDS methodology. The results showed that the majority of people had inadequate vitamin D intake, well below the Dietary Reference Values.
Article
Chemistry, Applied
Yanan Wang, Jiachen Shi, Yong-Jiang Xu, Chin-Ping Tan, Yuanfa Liu
Summary: This study investigates the variations in lipid digestion profiles among individuals of different ages using in vitro digestion models. The findings suggest that adults have a more comprehensive lipid digestion compared to infants, and infants tend to release shorter chain length and more saturated free fatty acids during digestion. Additionally, the particle sizes in the stomach of the elderly were consistently larger. This study enhances our understanding of how lipids with different degrees of unsaturation undergo digestion in diverse age groups.
Article
Chemistry, Applied
Hyunjong Yu, Huisu Kim, Pahn-Shick Chang
Summary: Chitosan-pectin emulsion-filled hydrogel (EFH) was developed to enhance the bioaccessibility of lipophilic bioactive compounds through intestinal delivery. The EFH, prepared without crosslinking agents, demonstrated improved mechanical strength and compactness with higher pectin concentration. It retained the emulsion at pH 2.0 and released it at pH 7.4, resulting in enhanced release of free fatty acids and improved bioaccessibility of curcumin.
Article
Chemistry, Applied
Tongze Zhang, Siqi Hong, Jia-Rong Zhang, Pin-He Liu, Siyi Li, Zixian Wen, Jianwei Xiao, Guirong Zhang, Olivier Habimana, Nagendra P. Shah, Zhongquan Sui, Harold Corke
Summary: Lactic acid fermentation significantly affects the morphology and physicochemical properties of proso millet starch, including the formation of surface indentations and small pores, decrease in gelatinization temperatures, and changes in hardness and adhesiveness.
Article
Chemistry, Applied
Liqin Kong, Feng Hong, Peng Luan, Yiping Chen, Yaoze Feng, Ming Zhu
Summary: This study presents a novel impedance biosensor using composite nanomaterials and T1R1 as a signal probe, which can competitively and ultra-sensitively detect umami intensity. The biosensor exhibits exceptional analytical performance and is suitable for food flavor evaluation.
Article
Chemistry, Applied
Kunying Lv, Yixin Yang, Qilong Li, Ran Chen, Liang Deng, Yiwei Zhang, Ning Jiang
Summary: Horse's milk, with its high nutritional value and low allergenic proteins, could be a substitute for cow's milk in infant consumption. A proteomic method was used to identify and compare milk fat globule membrane (MFGM) and whey proteins from different horse breeds. The study found differences in protein composition and functionality, which could support the development of formulas more suitable for human infants.
Article
Chemistry, Applied
Enrique Jacobo Diaz-Montana, Helene Brignot, Ramon Aparicio-Ruiz, Thierry Thomas- Danguin, Maria Teresa Morales
Summary: Sensory perception of virgin olive oil is influenced by phenols and volatiles, which are affected by the composition of the oil and biological factors. This study investigated the effect of saliva and phenols on the release of volatiles, and found that the presence of phenols decreased the release of saturated volatiles.
Article
Chemistry, Applied
Wei Zhou, Rui Zhang, Zhen Cai, Fangfang Wu, Yong Hu, Chao Huang, Kun Hu, Yun Chen
Summary: Environmentally friendly and outstanding pH-responsive cationic starch nanoparticles (CSNP) were prepared from pH-sensitive starch. CSNP exhibited nanosize and regular sphere, highly free-flowing molecular chains, and demonstrated excellent pH responsiveness through multiple emulsion/demulsification transitions.
Article
Chemistry, Applied
Andrea Koo, Vinayak Ghate, Weibiao Zhou
Summary: This study suggests that direct seeding may negatively affect the nutritional quality of crops, causing a decrease in ascorbic acid, vitamin K, and total glucosinolate content.
Article
Chemistry, Applied
Tonghao Du, Yazhou Xu, Xiaoyan Xu, Shijin Xiong, Linli Zhang, Biao Dong, Jinqing Huang, Tao Huang, Muyan Xiao, Tao Xiong, Mingyong Xie
Summary: This study successfully improved the ACE inhibitory activity of black sesame seeds by fermenting them with Lactobacillus Plantarum NCU116 and hydrolyzing them using acid protease. The RF-PSO model was used to predict the ACE inhibitory activity during the hydrolysis process. Eight peptides with ACE inhibitory activity were identified from fermented black sesame seed hydrolysates after separation and screening.
Article
Chemistry, Applied
Yao Liu, Songyi Lin, Kexin Liu, Shan Wang, Qiaozhen Liu, Na Sun
Summary: This study analyzed the structural changes of shrimp proteins during digestion, predicted the immunodominant epitopes, and validated their allergenicity. The results showed that shrimp proteins were degraded into peptides during digestion, but still carried IgE epitopes that trigger allergic reactions.
Article
Chemistry, Applied
Tiantian Fu, Hongwei Cao, Yu Zhang, Xiao Guan
Summary: This study investigates the impact of milling on the active components in rice, with a focus on the stability and bioaccessibility of phenols, VB1, and alpha-GABA during cooking and digestion. The findings show that milling exacerbates the instability of gamma-GABA during cooking and VB1 during digestion, and it affects the bioaccessibility of these active compounds.
Article
Chemistry, Applied
Zhihao Yang, Yanru Hou, Min Zhang, Puxin Hou, Chang Liu, Lu Dou, Xiaoyu Chen, Lihua Zhao, Lin Su, Ye Jin
Summary: This study investigated the molecular mechanism of feeding regimes on lamb flavor by using TMT labeling combined with MS. The results showed that pasture-fed groups had higher levels of amino acids and volatile flavor substances compared to concentrate-fed groups. Additionally, several differentially abundant proteins associated with lamb flavor were identified.
Article
Chemistry, Applied
Zixuan Xie, De Zhang, Junyu Zhu, Qianqian Luo, Jun Liu, Jingtao Zhou, Xiaoyong Wang, Yuqiong Chen, Zhi Yu, Dejiang Ni
Summary: This study investigated the acidification of aroma-enhanced black tea during storage. Analysis of non-volatile substances and organic acids using UPLC-Q-TOF/MS and HPLC revealed a decrease in soluble sugars and amino acids, while an increase in organic acids such as oxalic acid, malic acid, and quinic acid. In vitro experiments further demonstrated that the acidification is a result of the decomposition of sugars and amino acids by heating, as well as the oxidation of aromatic aldehydes. Additionally, the study showed that the taste composition of tea infusion is altered, with reduced amino acids, catechins, soluble sugars, and flavonoids. This research provides a theoretical basis for improving the quality of black tea.
Article
Chemistry, Applied
Lin Wang, Falai Ma, Zihan Li, Yan Zhang
Summary: This study developed time-temperature integrators based on amyloglucosidase@Cu3(PO4)2 nanoflowers for monitoring the freshness of chilled pork. The results showed that the integrators were highly reliable and accurate in predicting the quality of chilled pork.
