Article
Endocrinology & Metabolism
Yun Shen, Yahui Wu, Minghan Fu, Kai Zhu, Jinsheng Wang
Summary: This study reveals a significant association between weight-adjusted-waist index (WWI) and hepatic steatosis, suggesting that WWI may serve as a simple anthropometric index to predict the development of hepatic steatosis. The positive association between WWI and hepatic steatosis is stronger in individuals with excessive alcohol intake and hypertension. Although the linear relationship between WWI and liver fibrosis is not significant, a U-shaped association is observed, indicating a negative correlation at lower WWI values and a positive correlation at higher WWI values.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Immunology
Ruijie Xie, Mengde Xiao, Lihong Li, Nengqian Ma, Mingjiang Liu, Xiongjie Huang, Qianlong Liu, Ya Zhang
Summary: This study investigated the relationship between the systemic immune-inflammation index (SII) and hepatic steatosis and fibrosis. The results showed that increased SII levels are associated with hepatic steatosis but not with liver fibrosis. More large-scale prospective studies are needed to confirm these findings.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Multidisciplinary Sciences
Fabio Lucio Stahlschmidt, Jean Rodrigo Tafarel, Carla Martinez Menini-Stahlschmidt, Cristina Pellegrino Baena
Summary: This study evaluated the influence of fibrosis on the measurement of steatosis using the hepatorenal index, and found that the index is not appropriate for estimating steatosis in livers with advanced fibrosis.
Article
Endocrinology & Metabolism
YipHan Chin, Jieyu Lim, Gwyneth Kong, Cheng Han Ng, Rachel Goh, Mark Muthiah, Anurag Mehta, Bryan Chong, Chaoxing Lin, Kai En Chan, William Kong, Kian Keong Poh, Roger Foo, Ping Chai, Tiong-Cheng Yeo, Adrian F. Low, Chi Hang Lee, Huay Cheem Tan, Mark Yan-Yee Chan, Poay-Huan Richards, Poay-Huan Loh, Nicholas W. S. Chew
Summary: This study examined the prevalence and prognosis of hepatic steatosis and fibrosis in patients with post-acute myocardial infarction (AMI). The results showed that both hepatic steatosis and fibrosis are common in AMI patients and are associated with mortality. Hepatic steatosis and fibrosis could help stratify the risk of AMI patients.
DIABETES OBESITY & METABOLISM
(2023)
Article
Endocrinology & Metabolism
Jingli Wen, Yuanyuan Fei, Ling Yuan, Kai Li, Qian Xu, Xueyan Cao, Jing Su, Yujing Zhu, Zhenjiang Zhang
Summary: This study investigated the association between different forms of folate and hepatic steatosis or liver stiffness in adolescents. The results showed that serum total folate and 5-Methyl-tetrahydrofolate were negatively correlated with hepatic steatosis or liver stiffness, and BMI played a major mediating role in this relationship.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Biology
Kyungchul Song, Nak-Hoon Son, Dong Ryul Chang, Hyun Wook Chae, Hyun Joo Shin
Summary: Hepatic steatosis is a growing concern among children, and an effective evaluation method is needed. This study found that ultrasound attenuation imaging (ATI) can be used for quantifying and staging pediatric hepatic steatosis, helping to identify children who require liver biopsy and early treatment.
Article
Nutrition & Dietetics
Sara Policarpo, Sofia Carvalhana, Ana Craciun, Ricardo Rios Crespo, Helena Cortez-Pinto
Summary: This study aimed to assess the dietary intake of metabolic-associated fatty liver disease (MAFLD) patients and explore the relationship between its inflammatory characteristics, liver fibrosis, and alcohol intake. The results showed that alcohol intake was associated with higher energy and certain nutrient intake, but there was no correlation between fibrosis severity or alcohol consumption and inflammatory characteristics.
Article
Medicine, General & Internal
Maciej Krasnodebski, Marcin Morawski, Jan Borkowski, Karolina Grat, Jan Stypulkowski, Michal Skalski, Andriy Zhylko, Marek Krawczyk, Michal Grat
Summary: This study found that skin autofluorescence (SAF) measurements can correlate with the quality of liver parenchyma and may serve as a non-invasive method for detecting hepatic steatosis and fibrosis in patients prior to liver resection.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Medicine, General & Internal
Claudia Veltkamp, Shuai Lan, Eleni Korompoki, Karl-Heinz Weiss, Hartmut Schmidt, Helmut K. Seitz
Summary: IBD patients often develop liver problems such as hepatic steatosis and fibrosis. Factors associated with hepatic steatosis include age, BMI, disease duration, and specific serum activities. Hepatic fibrosis is more common in CD patients.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Nutrition & Dietetics
Atsushi Nakamura, Tsubasa Yoshimura, Hitoshi Asakura
Summary: This study investigated the relationship between hepatic fat loss and malnutrition in chronic liver disease using magnetic resonance imaging. The results showed that decreased body fat mass and triglycerides, as well as increased nutritional assessment score, were associated with hepatic fat loss. Furthermore, hepatic fat loss and Child-Pugh score were identified as independent prognostic factors for patients with cirrhosis. These findings emphasize the importance of preserving liver fat content in nutritional therapy for cirrhotic patients.
EUROPEAN JOURNAL OF CLINICAL NUTRITION
(2023)
Article
Gastroenterology & Hepatology
Yi-Cheng Chen, Chao-Wei Hsu, Wen-Juei Jeng, Chun-Yen Lin
Summary: This study aimed to investigate the association between hepatic steatosis (HS) and liver fibrosis in patients with chronic hepatitis B (CHB) and found that age, body mass index (BMI), genotype, platelet count, and HAI score were independent factors for advanced liver fibrosis. Hepatic steatosis was not significantly related to liver fibrosis, while the grade of necroinflammation was associated with liver fibrosis progression.
DIGESTIVE DISEASES AND SCIENCES
(2021)
Article
Medicine, General & Internal
Seogoo Han, Gi-Ho Sung, Sangheun Lee, Ki Jun Han, Hyun-Jeong Han
Summary: This study aimed to investigate the associations between serum cadmium levels and the degree of liver steatosis and fibrosis. The results showed that serum cadmium concentrations were significantly associated with elevated ALT levels, significant liver steatosis, and fibrosis.
Article
Nutrition & Dietetics
Zhengyu Hu, Yan Li, Bingwei Ma, Saifei Lei, Xingchun Wang
Summary: Vitamin C and ferritin are closely related to metabolic disorders, and this study found that Vitamin C has a protective effect on non-alcoholic fatty liver disease (NAFLD), while ferritin is a risk factor for NAFLD. Further experiments showed that Vitamin C alleviates NAFLD and maintains iron homeostasis by suppressing ferritin and inducing the labile iron pool (LIP).
FRONTIERS IN NUTRITION
(2022)
Article
Multidisciplinary Sciences
Zhongbao Zuo, Huaizhong Cui, Miaochan Wang, Congxiang Huang, Jing Wu, Chengjing Tao, Zhaoyi Li, Chunli Yang, Kenv Pan, Jianfeng Bao, Shourong Liu, Aifang Xu
Summary: This study evaluated the diagnostic value of FibroTouch and serological models for staging hepatic fibrosis in chronic liver diseases. The results showed that FibroTouch has a higher diagnostic value compared to noninvasive serological models in staging fibrosis.
Article
Endocrinology & Metabolism
Wei Zhang, Yuhua Li, Shangjian Li, Jingqi Zhou, Kai Wang, Zhibin Li, Ning Chen, Xueqin Chen
Summary: The association between liver steatosis and fibrosis with bone mineral density (BMD) and risk of osteopenia/osteoporosis in type 2 diabetes mellitus (T2DM) patients is limited and conflicting. Obesity may have a significant impact on these associations.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Ruijie Xie, Yiliang Liu, Jiusong Wang, Chenhao Zhang, Meimei Xiao, Mingjiang Liu, Ya Zhang
Summary: This study investigated the relationship between cadmium exposure and bone mineral density (BMD) in adults, and found significant differences across gender and race. It was found that cadmium exposure was negatively associated with BMD, particularly in non-Hispanic black females.
BIOLOGICAL TRACE ELEMENT RESEARCH
(2023)
Article
Dermatology
Ruijie Xie, Qianlong Liu, Ya Zhang, Chengyi Guo, Xiongjie Huang, Mingjiang Liu
Summary: This study presents a self-contained infrared wireless thermometry device for monitoring flap blood supply and evaluates its effectiveness on porcine flap models. Results show that the device outperforms traditional clinical observation methods in monitoring blood supply, and it has the potential to be used as a routine means of postoperative blood supply monitoring in flap surgery due to its low cost, real-time monitoring, simple operation, and non-invasive features.
INTERNATIONAL WOUND JOURNAL
(2023)
Letter
Engineering, Biomedical
Kunming Cheng, Qiang Guo, Yongbin He, Yanqiu Lu, Ruijie Xie, Cheng Li, Haiyang Wu
Summary: Sports medicine, a vital part of orthopedics, aims to preserve, restore, improve, and rebuild the human motor system. This interdisciplinary field has attracted the interest of both the orthopedic community and artificial intelligence (AI). In this study, the potential applications of GPT-4 in sports medicine, including diagnostic imaging, exercise prescription, medical supervision, surgery treatment, sports nutrition, and science research, were summarized. Our opinion is that GPT-4 is unlikely to render sports physicians obsolete, but instead, it could become an indispensable scientific assistant for them in the future.
ANNALS OF BIOMEDICAL ENGINEERING
(2023)
Letter
Engineering, Biomedical
Kunming Cheng, Yongbin He, Cheng Li, Ruijie Xie, Yanqiu Lu, Shuqin Gu, Haiyang Wu
Summary: In this study, we engaged in a conversation with ChatGPT to explore its reflections and suggestions on the sudden outbreak of Mpox in 2022 from an AI perspective. The aim was to enhance our understanding of Mpox through the lens of AI and examine the potential for human-AI collaboration in future epidemic and pandemic prevention and containment efforts.
ANNALS OF BIOMEDICAL ENGINEERING
(2023)
Letter
Engineering, Biomedical
Kunming Cheng, Zhiyong Li, Cheng Li, Ruijie Xie, Qiang Guo, Yongbin He, Haiyang Wu
Summary: The emergence of AI technology presents unprecedented opportunities for joint arthroplasty surgery. However, despite numerous articles reporting the potential roles of ChatGPT/GPT-4 in various fields, there are currently no studies discussing the potential of GPT-4 as an AI-powered virtual assistant for specialized joint arthroplasty surgeons. This study summarizes the five major roles of GPT-4, including scientific research, disease diagnosis, treatment options, preoperative planning, intraoperative support, and postoperative rehabilitation. Ethical considerations and data protection are also important to ensure the responsible use of AI.
ANNALS OF BIOMEDICAL ENGINEERING
(2023)
Article
Cardiac & Cardiovascular Systems
Ruijie Xie, Ya Zhang
Summary: This study used the Food and Nutrient Database for Dietary Studies and the National Health and Nutrition Examination Survey to investigate the relationship between flavonoid intake and nonalcoholic fatty liver disease. The results showed a negative association between flavonoid intake and hepatic steatosis and fibrosis. The study also found gender differences and identified a threshold effect at an intake level of 287.25 mg/day.
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
(2023)
Review
Oncology
Nengqian Ma, Zhangzhan Li, Jingting Yan, Xianrong Liu, Liyan He, Ruijie Xie, Xianzhou Lu
Summary: This study investigated the role of ubiquitin-conjugating enzyme E2 T (UBE2T) and its associated pathways in the pathogenesis and treatment strategies of pan-cancer. The results showed that UBE2T plays an important role in pan-cancer and may serve as a biomarker and therapeutic target for diagnosis, prognosis, and treatment.
Article
Public, Environmental & Occupational Health
Ya Zhang, Mingjiang Liu, Ruijie Xie
Summary: This study suggests that high levels of cadmium exposure are associated with whole-body aging. By analyzing urinary cadmium and molecular biomarkers, we found a positive relationship between urinary cadmium and phenotypic age, and this association differs by sex, age, and smoking status.
Article
Cardiac & Cardiovascular Systems
Ruijie Xie, Xiaozhu Liu, Haiyang Wu, Mingjiang Liu, Ya Zhang
Summary: This study investigated the association between the Systemic Immune-Inflammation Index (SII) and abdominal aortic calcification (AAC) in adults. The results showed a positive association between SII and AAC, with a 4% increase in the risk of severe AAC for each 100-unit increase in SII among participants over 40 years old. SII has the potential to improve AAC prevention in the general population.
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
(2023)
Article
Oncology
Yuan Zhao, Jing Zhao, Ruijie Xie, Yu Zhang, Ya Xu, Jing Mao, Cheng Yan, Yi Sun
Summary: This study investigated the relationship between poverty index and HPV infection status among Americans aged 20 and older using data from NHANES 2003-2016. The results showed a significant negative correlation between poverty index and HPV infection, which was consistent across different subgroups. These findings are of great significance for preventing HPV infection and improving HPV screening accuracy.
FRONTIERS IN ONCOLOGY
(2023)
Article
Geriatrics & Gerontology
Ruijie Xie, Zhongxing Ning, Mengde Xiao, Lihong Li, Mingjiang Liu, Ya Zhang
Summary: This study aimed to investigate the association between the dietary inflammatory index (DII) and biological aging in US adults using quantitative indicators. The findings revealed a significant positive correlation between higher DII scores (indicating a greater pro-inflammatory dietary potential) and biological aging. These findings may contribute to developing aging prevention strategies through dietary interventions.
AGING CLINICAL AND EXPERIMENTAL RESEARCH
(2023)
Article
Dermatology
Qiang Guo, Wanqing Li, Ruijie Xie, Yulin Wang, Yuchen Xie, Kunming Cheng, Zhiming Sun
Summary: Macrophages play a crucial role in wound healing and have been the focus of increasing research. This study conducted a comprehensive bibliometric analysis and found that the number of publications on macrophages and wound healing has been growing exponentially. The United States and China are the leading contributors to this field, and the application of biomaterials is a major research area. Future research will focus on diabetic wound healing and regulating macrophage polarization.
INTERNATIONAL WOUND JOURNAL
(2023)
Review
Environmental Sciences
Attila Csaba Kondor, Anna Viktoria Vancsik, Laszlo Bauer, Lili Szabo, Zoltan Szalai, Gergely Jakab, Gabor Maasz, Marta Pedrosa, Maria Jose Sampaio, Ana Rita Lado Ribeiro
Summary: This review provides a critical overview of research on the removal efficiency of priority substances and compounds of emerging concern through bank filtration, discussing influencing factors and future challenges. The findings show that the efficiency of bank filtration is influenced by multiple factors and varies for different substances.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Xinyan Wang, Shuai Zhang, Huihui Yan, Zhao Ma, Yunshan Zhang, Haining Luo, Xueli Yang
Summary: This study investigated the association between ambient PM2.5, O3 pollution, and ovarian reserve in reproductive-aged Chinese women. The results showed that increased exposure to PM2.5 and O3 was associated with decreased AMH levels, indicating reduced ovarian reserve. Notably, the effects of O3 exposure on ovarian reserve were different from those of PM2.5 exposure.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Tingting Ma, Yanjuan Ding, Fengjiao Xu, Chen Zhang, Min Zhou, Ya Tang, Yanrong Chen, Yating Wen, Rufei Chen, Bin Tang, Shigui Wang
Summary: The dragonfly species Orthetrum albistylum can accumulate heavy metals, and its heat shock protein genes have the potential to serve as biomarkers for monitoring environmental pollutants.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Naoto Ishiwaka, Koya Hashimoto, Masayoshi K. Hiraiwa, Francisco Sanchez-Bayo, Taku Kadoya, Daisuke Hayasaka
Summary: Systemic insecticides and rising temperatures have combined effects on the abundance of Odonata nymphs in paddy fields. The standalone effect of insecticide exposure decreased the Odonata community, while nymphs decreased synergistically with temperature rise in paddy water. However, the impacts of each stressor alone varied among species.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Marco Vecchiato, Carlo Barbante, Elena Barbaro, Francois Burgay, Warren R. L. Cairns, Alice Callegaro, David Cappelletti, Federico Dallo, Marianna D'Amico, Matteo Feltracco, Jean-Charles Gallet, Andrea Gambaro, Catherine Larose, Niccolo Maffezzoli, Mauro Mazzola, Ivan Sartorato, Federico Scoto, Clara Turetta, Massimiliano Varde, Zhiyong Xie, Andrea Spolaor
Summary: The Arctic region is facing contamination from long-range pollution and local human activities. Polycyclic Aromatic Hydrocarbons (PAHs) are used as environmental indicators for emission, transport, and deposition processes. Research conducted in the Arctic surface snow in Ny-Ålesund, Svalbard from October 2018 to May 2019 shows that long-range inputs of PAHs mainly occur in winter, while the most abundant analyte retene exhibits opposite seasonal trends.
ENVIRONMENTAL POLLUTION
(2024)
Review
Environmental Sciences
Maoshui Zhuo, Zhijie Chen, Xiaoqing Liu, Wei Wei, Yansong Shen, Bing-Jie Ni
Summary: This paper discusses the application of three catalytic processes (photocatalysis, electrocatalysis, and biocatalysis) in the management of microplastic pollution, and introduces the efficiency and catalytic mechanisms of different catalysts. It also proposes the development prospects for sustainable management of microplastic pollution.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Shiyu Chen, Zhenzhen Shi, Qiang Zhang
Summary: In this study, a human physiologically based pharmacokinetic (PBPK) model of diethyl phthalate (DEP) was developed to assess its toxicity. The model considers the distribution and metabolism of DEP and its active metabolite monoethyl phthalate (MEP) in different tissue compartments. Sensitivity analysis and Bayesian Markov chain Monte Carlo (MCMC) simulations were performed to evaluate the uncertainty and variability of the model parameters. The results suggest that dermal absorption is an important route of exposure to DEP in the environment.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Bangguo Wang, Lijing Wang, Wenxi Cen, Tao Lyu, Peter Jarvis, Yang Zhang, Yuanxun Zhang, Yinghui Han, Lei Wang, Gang Pan, Kaili Zhang, Wei Fan
Summary: This study investigates the feasibility and mechanisms of a chemical-free nanobubble-based AOP for treating organic micropollutants in water. The results show that the oxygen nanobubble AOP has a significantly higher removal efficiency compared to air and nitrogen nanobubbles. The treatment performance is not affected by pH and the presence of ions. Higher initial concentrations of the micropollutant lead to slower treatment processes, but similar removal performance is achieved in the end. The presence of organic matter reduces the removal rate of the micropollutant. The results have practical feasibility for water and wastewater treatment.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Yingmei Huang, Jicai Yi, Yao Huang, Songxiong Zhong, Bin Zhao, Jing Zhou, Yuxuan Wang, Yiwen Zhu, Yanhong Du, Fangbai Li
Summary: This study investigates the impact of biochar on methylmercury (MeHg) accumulation in rice. The results show that biochar reduces MeHg levels in paddy soils by decreasing bioavailable Hg and microbial Hg methylation. Additionally, biochar decreases the uptake and translocation of MeHg in rice plants, resulting in a reduction of MeHg accumulation in rice grains.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Nengde Zeng, Fei Huang, Jiani Du, Chenghao Huang, Qian Yang, Xinhua Zhan, Baoshan Xing
Summary: This study investigates the protein targets and protein-ligand interactions related to PAH contamination in crop xylem sap using computational tools. The results show that phenanthrene has a more pronounced effect on the xylem sap proteins of maize and wheat, with maize DEPs associated with lipid biosynthesis and wheat DEPs exhibiting an increase in ABC transporters. This study provides insights into the regulation and movement of PAHs within plant xylem.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Xinwei Chen, Hao Ma, Run Wang, Man Wang, Binbin Zhu, Yanqing Cong, Xiayue Zhu, Guoqin Wang, Yi Zhang
Summary: Co3O4/TiO2-NRs electrodes with excellent photoresponse were prepared via plasma-assisted modification of Co3O4 on TiO2. The combination of Co3O4 and TiO2 improved the light utilization efficiency and showed potential for degradation of pollutants.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Wenjing Ji, Liying Song, Jing Wang, Hongqing Song
Summary: This study conducted a life-cycle assessment to examine the correlation between natural gas consumption and carbon emissions in different end uses in China. The results showed that both natural gas consumption and life-cycle carbon emissions have been increasing since 2017. Significant variations in NG life-cycle carbon emissions were found across different provinces and sectors, highlighting the need for targeted efforts to reduce carbon emissions.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Youyi Chen, Boxuan Zhang, Pojun Zhang, Guogui Shi, Hao Liang, Wu Cai, Jingyu Gao, Sumin Zhuang, Kaiyin Luo, Jiaqi Zhu, Chaoxiang Chen, Kunyu Ma, Jinrong Chen, Chun Hu, Xueci Xing
Summary: The synergistic effects of trace sulfadiazine and cast-iron corrosion scales on the formation of disinfection by-products in drinking water distribution systems were investigated. The presence of magnetite resulted in increased concentrations of DBPs due to the higher microbial activity and enhanced microbial extracellular electron transport pathway. The study highlights the importance of considering trace antibiotics pollution and corrosion scales in water sources for DBP control.
ENVIRONMENTAL POLLUTION
(2024)
Review
Environmental Sciences
Bishwa Raj Pokharel, Vijay Sheri, Manoj Kumar, Zhiyong Zhang, Baohong Zhang
Summary: This review summarizes the interactions, uptake, and transport of aluminum nanoparticles (Al-NPs) in plants, highlighting their negative effects on plant growth and development, as well as their potential to alter plant defense systems and gene expression.
ENVIRONMENTAL POLLUTION
(2024)
Article
Environmental Sciences
Yonglu Wang, Fengsong Zhang, Xiaoyong Liao, Xiao Yang, Guixiang Zhang, Liyun Zhang, Chaojun Wei, Pengge Shi, Jiongxin Wen, Xiaorong Ju, Can Xu, Yang Liu, Ying Lan
Summary: This study aims to explore the effects of thiencarbazone-methyl center dot isoxaflutole on soil microflora and the potential mitigation mechanisms to bacterial communities. It was found that increasing the application of thiencarbazone-methyl center dot isoxaflutole resulted in increased stress on soil bacterial community structure and diversity. Increasing soil pH was recognized as a key factor in improving the diversity and structure of soil microflora. Supplemental use of nitrapyrin or modified attapulgite can increase soil pH and improve bacterial diversity.
ENVIRONMENTAL POLLUTION
(2024)