期刊
JOURNAL OF OBSTETRICS AND GYNAECOLOGY
卷 36, 期 6, 页码 719-721出版社
TAYLOR & FRANCIS INC
DOI: 10.3109/01443615.2016.1148128
关键词
Leptin; IL-6; TNF-; cord blood; term newborn; mode of delivery
In the development of the foetal immune system, cytokines play an important role in its function. Therefore, we sought to determine whether the mode of delivery affects the expression of leptin, IL-6 and TNF- in umbilical cord blood in healthy term newborns. We collected 125 samples of umbilical cord blood to analyse leptin, IL-6 y TNF- levels with multiplex immunoassay (MIA). The samples were classified according to mode of delivery: vaginal delivery (VD) and caesarean section (CS). Leptin and IL-6 had higher concentrations in umbilical cord blood in VD than in CS: 42.55ng/ml (11.92-104.28) versus 35.20ng/ml (3.26-9326.76), p = 0.039; 9.32pg/ml (1.13-2020.31) versus 3.81pg/ml (0.52-834.69) p<0.001, respectively. Also, a weak correlation between TNF- and IL-6 was found (r=0.238, p=0.007). The most important finding in our study was the differential concentrations of leptin and IL-6 according to mode of delivery.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据