Article
Nutrition & Dietetics
Rui Zhao, Leilei Zhou, Gang Lei, Shanshan Wang, Yan Li, Xuefeng Yang, Guoping Xiong, Liping Hao
Summary: This study found a significant positive association between dietary acid load during early pregnancy and the risk of GDM in a Chinese population, suggesting that the reduction of food sources of dietary acid load may be an effective strategy for preventing the risk of GDM.
FRONTIERS IN NUTRITION
(2022)
Article
Cardiac & Cardiovascular Systems
Parvin Mirmiran, Zeinab Houshialsadat, Zahra Bahadoran, Sajjad Khalili-Moghadam, Mohammad Karim Shahrzad, Fereidoun Azizi
Summary: This study failed to find independent associations between dietary acid load and the incidence of cardiovascular diseases among an Asian population.
BMC CARDIOVASCULAR DISORDERS
(2021)
Article
Pharmacology & Pharmacy
E. E. Ozturk, H. Yildiz
Summary: This case-control study aimed to evaluate the relationship between dietary acid load and the risk of type 2 diabetes. The findings suggest that a high acid load in the diet may increase the risk of type 2 diabetes.
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
(2023)
Review
Nutrition & Dietetics
Alvaro Luis Ronco, Maximilian Andreas Storz
Summary: Dietary acid load (DAL) is recognized as a risk factor for several chronic disorders. Recent evidence suggests that an elevated DAL could increase the risk for several cancers. This review summarizes the potential role of DAL in Uruguayan cancer patients and outlines the mediating pathophysiological pathways.
Article
Nutrition & Dietetics
Min Zhang, Chen Ye, Ruoyu Wang, Zongfeng Zhang, Xiaojie Huang, Mairepaiti Halimulati, Meng Sun, Yuxin Ma, Zhaofeng Zhang
Summary: This study examines the association between dietary acid load and hyperuricemia in Chinese adults. The results show that potential renal acid load is positively correlated with the prevalence of hyperuricemia, while net endogenous acid production is not significantly associated. Additionally, increased intake of fat, protein, and animal protein is linked to a higher risk of hyperuricemia.
Article
Nutrition & Dietetics
Feng Lin, Min Zhang, Ruoyu Wang, Meng Sun, Zongfeng Zhang, Yanjiang Qiao, Zhaofeng Zhang
Summary: This study found that dietary acid load is positively associated with the risk of hypertension, with higher acid load scores being linked to a greater likelihood of developing hypertension. This association was more significant in men than in women, and no significant association was observed in participants younger than 60 years old. These findings suggest that a diet with a low acid load may be beneficial for lowering blood pressure.
Article
Endocrinology & Metabolism
Mariam Alatrach, Christina Agyin, Carolina Solis-Herrera, Olga Lavryneko, John Adams, Amalia Gastaldelli, Curtis Triplitt, Ralph A. DeFronzo, Eugenio Cersosimo
Summary: This study found that SGLT2 inhibitors have an effect on the increase of endogenous glucose production (EGP) in patients with type 2 diabetes after oral glucose intake. Despite elevated plasma insulin and glucagon, the stimulation of EGP was observed, suggesting that additional factors may be involved.
Article
Nutrition & Dietetics
Maximilian Andreas Storz, Alvaro Luis Ronco
Summary: This study investigated the association between dietary acid load (DAL) and serum total testosterone concentrations of men, and found no significant correlation between DAL and testosterone levels.
Article
Nutrition & Dietetics
Maximilian Andreas Storz, Alvaro Luis Ronco, Mauro Lombardo
Summary: The gluten-free diet (GFD) improves clinical symptoms for celiac disease patients, but there is controversy over its effects on healthy individuals. This study found that adopting a GFD is associated with lower dietary acid load in the US population.
Article
Food Science & Technology
Niki Bahrampour, Cain C. T. Clark
Summary: This study suggests that a higher dietary acid load may be associated with musculoskeletal pain in adults.
FOOD SCIENCE & NUTRITION
(2022)
Article
Urology & Nephrology
Najmeh Seifi, Hossein Bahari, Mina Nosrati, Glareh Koochakpoor, Zahra Alizadeh Hassani, Arezoo Rastegarmoghadam-Ebrahimian, Malihehsadat Abedsaeidi, Gordon A. Ferns, Majid Ghyour-Mobarhan
Summary: This study demonstrates a significant positive association between dietary acid load indices (PRAL and DAL) and the odds of hyperuricemia among Iranian adults.
INTERNATIONAL UROLOGY AND NEPHROLOGY
(2023)
Article
Nutrition & Dietetics
Jihyun Park, Mi Ri Ha, Juhyun Song, Oh Yoen Kim
Summary: The study found that cigarette smoking and dietary acid load are associated with an increased risk of chronic obstructive pulmonary disease in healthy, middle-aged Korean men, particularly among current smokers and individuals with higher DAL levels.
Article
Nutrition & Dietetics
Zahra Saeedirad, Shadi Ariyanfar, Morvarid Noormohammadi, Zeinab Ghorbani, Abdorreza Naser Moghadasi, Sahar Shahemi, Milad Ghanaatgar, Nasim Rezaeimanesh, Azita Hekmatdoost, Amir Ghaemi, Soodeh Razeghi Jahromi
Summary: This study investigated the association between dietary acid load (DAL) and multiple sclerosis (MS) using potential renal acid load (PRAL) and net endogenous acid production (NEAP) scores. The findings suggest that higher PRAL and NEAP scores may be associated with increased odds of MS, while a higher intake of plant-based protein may be protective.
Article
Urology & Nephrology
Stanley M. H. Yeung, Antonio W. Gomes-Neto, Maryse C. J. Oste, Else van den Berg, Jenny E. Kootstra-Ros, Jan Stephan F. Sanders, Stefan P. Berger, Juan Jesus Carrero, Martin H. De Borst, Gerjan J. Navis, Stephan J. L. Bakker
Summary: This study found that higher dietary acid load was associated with a higher risk of declining kidney function, and this association was partly mediated by venous bicarbonate, urinary ammonium, and net acid excretion.
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
(2021)
Review
Food Science & Technology
Nursel Sahin, Ugur Gunsen
Summary: Dietary acid load has an impact on cardiovascular diseases, but the research on this topic is limited and inconsistent. Possible mechanisms include excessive calcium and magnesium excretion, reduced urinary citrate excretion, and excessive cortisol production. Further studies are needed to explore the relationship between dietary acid load and cardiovascular diseases.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Article
Neurosciences
Kazumasa Yamagishi, Koutatsu Maruyama, Ai Ikeda, Masanori Nagao, Hiroyuki Noda, Mitsumasa Umesawa, Mina Hayama-Terada, Isao Muraki, Chika Okada, Mari Tanaka, Rie Kishida, Tomomi Kihara, Tetsuya Ohira, Hironori Imano, Eric J. Brunner, Tomoko Sankai, Takeo Okada, Takeshi Tanigawa, Akihiko Kitamura, Masahiko Kiyama, Hiroyasu Iso
Summary: The study aimed to investigate the association between dietary fiber intake and the risk of disabling dementia. The results showed that higher dietary fiber intake, especially soluble fiber, was associated with a lower risk of disabling dementia requiring care.
NUTRITIONAL NEUROSCIENCE
(2023)
Article
Nutrition & Dietetics
Paramita Khairan, Tomotaka Sobue, Ehab Salah Eshak, Tetsuhisa Kitamura, Motoki Iwasaki, Manami Inoue, Taiki Yamaji, Hiroyasu Iso, Shoichiro Tsugane, Norie Sawada
Summary: This study aimed to investigate the association between consumption of sugary drinks and gastric cancer (GC) risk in a Japanese population. The study found no association between sugary drink consumption and GC risk.
EUROPEAN JOURNAL OF CLINICAL NUTRITION
(2023)
Article
Transplantation
Yoshihisa Miyamoto, Ryoko Katagiri, Taiki Yamaji, Manami Inoue, Atsushi Goto, Motoki Iwasaki, Mitsuhiko Noda, Shoichiro Tsugane, Norie Sawada
Summary: This study investigated the association between chronic kidney disease (CKD) and cancer incidence. The findings suggest that a low estimated glomerular filtration rate (eGFR) is not significantly associated with an increased risk of total cancer incidence in patients with CKD, possibly due to the underpowered sample size and shared risk factors between CKD and cancer.
NEPHROLOGY DIALYSIS TRANSPLANTATION
(2023)
Article
Health Care Sciences & Services
Seigo Mitsutake, Yoshimitsu Takahashi, Aki Otsuki, Jun Umezawa, Akiko Yaguchi-Saito, Junko Saito, Maiko Fujimori, Taichi Shimazu, INFORM Study Grp
Summary: This study aims to improve strategies to provide reliable self-management information for chronic diseases online and identify populations facing barriers to internet use for health. The study found that patients with cancer and depression or anxiety disorder were more likely to seek online health information, while patients with chronic lung diseases were more likely to watch health-related videos on YouTube.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2023)
Article
Oncology
Shiori Nakano, Taiki Yamaji, Kouya Shiraishi, Akihisa Hidaka, Taichi Shimazu, Aya Kuchiba, Masahiro Saito, Fumihito Kunishima, Ryouji Nakaza, Takashi Kohno, Norie Sawada, Manami Inoue, Shoichiro Tsugane, Motoki Iwasaki
Summary: Although smoking is a modifiable risk factor for many cancers, its association with colorectal cancer in Asian populations is not clear. In a Japanese study, smokers were found to have a 2-fold higher risk of KRAS wild-type colorectal cancer compared to non-smokers. This is the first study to evaluate the association between smoking and colorectal cancer according to KRAS and BRAF mutation status in an Asian population.
Article
Nutrition & Dietetics
Rei Otsuka, Shu Zhang, Hikaru Ihira, Norie Sawada, Manami Inoue, Kazumasa Yamagishi, Nobufumi Yasuda, Shoichiro Tsugane
Summary: This study aimed to investigate the potential effect of dietary diversity on the risk of disabling dementia in a nationwide large-scale cohort of the Japanese population. The study found that dietary diversity was inversely associated with disabling dementia among women, but there was no significant association among men.
CLINICAL NUTRITION
(2023)
Article
Public, Environmental & Occupational Health
Rieko Kanehara, Atsushi Goto, Maki Goto, Toshiaki Takahashi, Motoki Iwasaki, Mitsuhiko Noda, Hikaru Ihira, Shoichiro Tsugane, Norie Sawada
Summary: We evaluated the validity of diabetes definitions using disease codes and antidiabetic drug prescriptions in the Japanese DPC data via medical chart review. The results showed that DPC data can accurately identify diabetes among inpatients using either diabetes codes alone or diabetes codes and/or prescriptions.
JOURNAL OF EPIDEMIOLOGY
(2023)
Article
Endocrinology & Metabolism
Daishi Hirano, Hiroyuki Unoki-Kubota, Toshiyuki Imasawa, Ritsuko Yamamoto-Honda, Hiroshi Kajio, Shigeo Yamashita, Yuka Fukazawa, Naoto Seki, Mitsuhiko Noda, Yasushi Kaburagi
Summary: In patients with type 2 diabetes with preserved renal function and normoalbuminuria, lower hemoglobin levels were identified as a risk factor for rapid decliners. The study also suggested that disturbed iron metabolism might contribute to the development of rapid renal function decline.
JOURNAL OF DIABETES INVESTIGATION
(2023)
Article
Endocrinology & Metabolism
Ryotaro Bouchi, Mitsuhiko Noda, Yasuaki Hayashino, Atsushi Goto, Katsuya Yamazaki, Hikari Suzuki, Toshiaki A. Furukawa, Kazuo Izumi, Masashi Kobayashi
Summary: This study aimed to compare the impact of a multifaceted lifestyle intervention by face-to-face approach (FFA) and telephone approach (TSC) on non-attendance from regular medical care in diabetes patients. The results showed that the effectiveness of intervention varied in different behavioral change stages for diet and exercise.
JOURNAL OF DIABETES INVESTIGATION
(2023)
Article
Oncology
Makiko Naka Mieno, Maria Yamasaki, Aya Kuchiba, Taiki Yamaji, Keigo Ide, Noriko Tanaka, Norie Sawada, Manami Inoue, Shoichiro Tsugane, Motoji Sawabe, Motoki Iwasaki
Summary: This study investigated the association between SNPs in the LPA region and cancer incidence and mortality in Japanese individuals. The results showed that none of the 25 SNPs in the LPAL2-LPA region were significantly associated with overall cancer incidence or mortality. However, some SNPs were found to be associated with stomach cancer incidence and mortality in men, as well as colorectal cancer incidence in men and prostate cancer incidence in carriers of certain SNPs. Further analysis using different cohorts is needed to confirm these findings.
CANCER EPIDEMIOLOGY
(2023)
Article
Oncology
Michiko Takahashi, Tomotaka Sobue, Ling Zha, Tetsuhisa Kitamura, Motoki Iwasaki, Manami Inoue, Taiki Yamaji, Shoichiro Tsugane, Norie Sawada
Summary: This study found a positive association between high consumption of n-3 PUFA and RCC risk in a Japanese population with higher fish intake compared to Western populations.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
(2023)
Article
Public, Environmental & Occupational Health
Nao Yamamoto, Keisuke Ejima, Luis M. Mestre, Arthur H. Owora, Manami Inoue, Shoichiro Tsugane, Norie Sawada
Summary: This study found that stable underweight and weight loss were strongly associated with a high risk of mortality in the Japanese population.
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
(2023)
Article
Immunology
Marina Terada, Taichi Shimazu, Junko Saito, Miyuki Odawara, Aki Otsuki, Akiko Yaguchi-Saito, Rina Miyawaki, Aya Kuchiba, Hirono Ishikawa, Maiko Fujimori, Gary L. Kreps
Summary: A study found that there is generally a low level of awareness and knowledge about HPV vaccines in the general population in Japan, particularly among males. Age, gender, education level, and health literacy have significant impacts on HPV awareness and knowledge.
Article
Public, Environmental & Occupational Health
Hiroshi Yatsuya, Kazumasa Yamagishi, Yuanying Li, Isao Saito, Yoshihiro Kokubo, Isao Muraki, Manami Inoue, Shoichiro Tsugane, Hiroyasu Iso, Norie Sawada
Summary: This study examined the associations of major risk factors for stroke with different types of stroke and subtypes of ischemic stroke. The results showed that hypertension is the most crucial risk factor for stroke prevention in Japan.
JOURNAL OF EPIDEMIOLOGY
(2023)
Article
Health Care Sciences & Services
Mina Honyashiki, Jeroen Decoster, William Tak Lam Lo, Taichi Shimazu, Kentaro Usuda, Daisuke Nishi
Summary: This study compares the processes of mental health policies in Belgium and Hong Kong, China, aiming to shift service delivery from hospital to community. It identifies similarities and differences in implementation strategies and provides insights for other countries seeking to make similar shifts.
HEALTH SERVICES INSIGHTS
(2023)
