Alterations in glycine metabolism in obesity and chronic metabolic diseases – an update on new advances

Genetic variants in ALDH1L1 and GLDC influence the serine-to-glycine ratio in Hispanic children

(2022) Sergey A Krupenko et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Integrated metagenomics and metabolomics analysis illustrates the systemic impact of the gut microbiota on host metabolism after bariatric surgery

(2022) Yeyoung Han et al.   DIABETES OBESITY & METABOLISM

Serum metabolomic signatures of gestational diabetes in South Asian and white European women

(2022) Claudia Sikorski et al.   BMJ Open Diabetes Research & Care

Genome-scale metabolic modelling of the human gut microbiome reveals changes of the glyoxylate and dicarboxylate metabolism in metabolic disorders

(2022) Ceri Proffitt et al.   iScience

High-risk Growth Trajectory Related to Childhood Overweight/Obesity and Its Predictive Model at Birth

(2022) Yan Chen et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

A randomized placebo-controlled clinical trial for pharmacological activation of BCAA catabolism in patients with type 2 diabetes

(2022) Froukje Vanweert et al.   Nature Communications

De Novo Glycine Synthesis Is Reduced in Adults With Morbid Obesity and Increases Following Bariatric Surgery

(2022) Hong Chang Tan et al.   Frontiers in Endocrinology

Effectiveness of Rice Germ Supplementation on Body Composition, Metabolic Parameters, Satiating Capacity, and Amino Acid Profiles in Obese Postmenopausal Women: A Randomized, Controlled Clinical Pilot Trial

(2021) Mariangela Rondanelli et al.   Nutrients

Metabolic signatures of greater body size and their associations with risk of colorectal and endometrial cancers in the European Prospective Investigation into Cancer and Nutrition

(2021) Nathalie Kliemann et al.   BMC Medicine

Amino acid differences between diabetic older adults and non-diabetic older adults and their associations with cardiovascular function

(2021) Jean-Paul Kovalik et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Glycine increases fat‐free mass in malnourished haemodialysis patients: a randomized double‐blind crossover trial

(2021) Laurence Genton et al.   Journal of Cachexia Sarcopenia and Muscle

Postprandial glycine as a biomarker of satiety: A dose-rising randomised control trial of whey protein in overweight women

(2021) Jia Jiet Lim et al.   APPETITE

Amino acid signatures in relation to polycystic ovary syndrome and increased risk of different metabolic disturbances

(2021) Zhenhong Ye et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Effects of Extreme Weight Loss on Cardiometabolic Health in Children With Metabolic Syndrome: A Metabolomic Study

(2021) Jingxin Liu et al.   Frontiers in Physiology

Obesity increases hepatic glycine dehydrogenase and aminomethyltransferase expression while dietary glycine supplementation reduces white adipose tissue in Zucker diabetic fatty rats

(2020) Rebecca M. Simmons et al.   AMINO ACIDS

Glycine-based treatment ameliorates NAFLD by modulating fatty acid oxidation, glutathione synthesis, and the gut microbiome

(2020) Oren Rom et al.   Science Translational Medicine

Infusion of donor feces affects the gut–brain axis in humans with metabolic syndrome

(2020) Annick V. Hartstra et al.   Molecular Metabolism

Dietary supplementation with inulin-propionate ester or inulin improves insulin sensitivity in adults with overweight and obesity with distinct effects on the gut microbiota, plasma metabolome and systemic inflammatory responses: a randomised cross-over trial

(2019) Edward S Chambers et al.   GUT

Genetic Determinants of Circulating Glycine Levels and Risk of Coronary Artery Disease

(2019) Qiong Jia et al.   Journal of the American Heart Association

Glycine Metabolism and Its Alterations in Obesity and Metabolic Diseases

(2019) Anaïs Alves et al.   Nutrients

The human plasma-metabolome: Reference values in 800 French healthy volunteers; impact of cholesterol, gender and age

(2017) Séverine Trabado et al.   PLoS One

Human gut microbes impact host serum metabolome and insulin sensitivity

(2016) Helle Krogh Pedersen et al.   NATURE

Branched-chain amino acid restriction in Zucker-fatty rats improves muscle insulin sensitivity by enhancing efficiency of fatty acid oxidation and acyl-glycine export

(2016) Phillip J. White et al.   Molecular Metabolism