Novel salts and cocrystals of the antifolate drug trimethoprim and their role in the enhancement of solubility and dissolution

Extensive Analyses on Expanding the Scope of Acid–Aminopyrimidine Synthons for the Design of Molecular Solids

(2022) Utsav Garg et al.   CRYSTAL GROWTH & DESIGN

Cocrystallization of Trimethoprim and Solubility Enhancement via Salt Formation

(2021) Qixuan Zheng et al.   CRYSTAL GROWTH & DESIGN

Validated RP-LC Methods for Investigation the Degradation Behavior of Acefylline: Application for Analysis in Two Binary Mixtures

(2020) Ola Mohamed EL-Houssini et al.   Current Pharmaceutical Analysis

Uric Acid Crystallization Interrupted with Competing Binding Agents

(2019) Victoria M. Hall et al.   CRYSTAL GROWTH & DESIGN

Screening, crystal structures and solubility studies of a series of multidrug salt hydrates and cocrystals of fenamic acids with trimethoprim and sulfamethazine

(2019) Biswajit Bhattacharya et al.   JOURNAL OF MOLECULAR STRUCTURE

Supramolecular hydrogen-bonding patterns in salts of the antifolate drugs trimethoprim and pyrimethamine

(2018) Robert Swinton Darious et al.   Acta Crystallographica Section C-Structural Chemistry

Challenges in Translational Development of Pharmaceutical Cocrystals

(2017) Dnyaneshwar P. Kale et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Pharmaceutical cocrystals: walking the talk

(2016) Geetha Bolla et al.   CHEMICAL COMMUNICATIONS

Correlating the melting point alteration with the supramolecular structure in aripiprazole drug cocrystals

(2016) Jagadeesh Babu Nanubolu et al.   CRYSTENGCOMM

The Cambridge Structural Database

(2016) Colin R. Groom et al.   Acta Crystallographica Section B-Structural Science Crystal Engineering and Materials

Tetramorphs of the Antibiotic Drug Trimethoprim: Characterization and Stability

(2015) D. Maddileti et al.   CRYSTAL GROWTH & DESIGN

SHELXT– Integrated space-group and crystal-structure determination

(2015) George M. Sheldrick   Acta Crystallographica A-Foundation and Advances

Cocrystals of the antibiotic trimethoprim with glutarimide and 3,3-dimethylglutarimide held together by three hydrogen bonds

(2015) Quoc Cuong Ton et al.   Acta Crystallographica Section C-Structural Chemistry

Crystal structure refinement withSHELXL

(2015) George M. Sheldrick   Acta Crystallographica Section C-Structural Chemistry

Comparison of silver and molybdenum microfocus X-ray sources for single-crystal structure determination

(2015) Lennard Krause et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

Investigation of supramolecular synthons and structural characterisation of aminopyridine-carboxylic acid derivatives

(2014) Madhukar Hemamalini et al.   Chemistry Central Journal

5-Fluorouracil solutions: NMR study of acid-base equilibrium in water and DMSO

(2014) Gulnas S. Abdrakhimova et al.   JOURNAL OF PHYSICAL ORGANIC CHEMISTRY

Design of Co-crystals/Salts of Aminopyrimidines and Carboxylic Acids through Recurrently Occurring Synthons

(2012) Samuel Ebenezer et al.   CRYSTAL GROWTH & DESIGN

Competition between the two-point and three-point synthon in cytosine–carboxylic acid complexes

(2012) Balasubramanian Sridhar et al.   CRYSTENGCOMM

Acid–base crystalline complexes and the pKa rule

(2012) Aurora J. Cruz-Cabeza   CRYSTENGCOMM

Use of pharmaceutical salts and cocrystals to address the issue of poor solubility

(2012) David P. Elder et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Pharmaceutical cocrystals and poorly soluble drugs

(2012) Ranjit Thakuria et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

A hydrogen bonded cocrystal with an unusual interweaving between the adjacent triple-helices

(2011) Amit Delori et al.   CRYSTENGCOMM

Hydrogen Bonding Patterns in Trimethoprimium Cinnamate 1.52 Hydrate

(2011) Annamalai Subashini et al.   JOURNAL OF CHEMICAL CRYSTALLOGRAPHY

Studies on trimethoprim:hydroxypropyl-β-cyclodextrin: aggregate and complex formation

(2010) Claudia Garnero et al.   CARBOHYDRATE RESEARCH

Determination of Dissociation Constants of Folinic Acid (Leucovorin), 5-Fluorouracil, and Irinotecan in Hydro-organic Media by a Spectrophotometric Method

(2010) Nurullah Şanli et al.   JOURNAL OF CHEMICAL AND ENGINEERING DATA

Bis[2,4-diamino-5-(3,4,5-trimethoxybenzyl)pyrimidin-1-ium]DL-malate

(2009) S. Franklin et al.   ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS

On the Solubility of Saccharinate Salts and Cocrystals

(2008) Claire L. Cooke et al.   CRYSTAL GROWTH & DESIGN