Article
Chemistry, Multidisciplinary
Yaxin Liu, Xiaomei Lu, Wen Zhou, Quli Fan
Summary: The study reports an RGD-conjugated cyanine dye, IR806-RGD, for NIR-II fluorescence imaging of tumors. Compared to the commonly used cyanine dye IR806, IR806-RGD shows improved tumor targeting capability and higher fluorescence intensity.
NEW JOURNAL OF CHEMISTRY
(2023)
Review
Biotechnology & Applied Microbiology
Wen Zhou, Likun Yin, Xuheng Zhang, Tingting Liang, Zixin Guo, Yaxin Liu, Chen Xie, Quli Fan
Summary: This minireview summarizes the recent advances in small molecule dyes-based nanotheranostics for NIR-II PA imaging and cancer therapy. It introduces NIR-II PA imaging-guided phototherapy and reviews phototherapy-based combination therapeutic systems. The conclusion and perspectives of this field are also discussed.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Chemistry, Multidisciplinary
Yeneng Dai, Fan Zhang, Kai Chen, Zhiquan Sun, Zhihang Wang, Yuwen Xue, Meixing Li, Quli Fan, Qingming Shen, Qi Zhao
Summary: This study presents a tumor microenvironment (TME) activated near-infrared window (NIR-II) phototheranostic nanoplatform. The nanoplatform, called Ag2S-Fe(III)-DBZ Pdots (AFD NPs), utilizes the principle of Forster resonance energy transfer (FRET). In normal tissues, the AFD NPs remain in an off state due to FRET between Ag2S QDs and DBZ Pdots. However, the NIR-II fluorescence signal of AFD NPs can be rapidly turned on in tumor tissues by the overexpressed GSH, achieving a superior tumor-to-normal tissue (T/NT) signal ratio. The AFD NPs also provide NIR-II photothermal therapy (PTT) and chemodynamic therapy (CDT) for cancer treatment.
Article
Engineering, Biomedical
Yingxin Zhu, Xianzhu Luo, Zihang Yu, Shihui Wen, Guochen Bao, Le Zhang, Cuiling Zhang, Yuezhong Xian
Summary: In this study, a hybrid nanoplatform was developed for photoactivatable therapy and deep tissue NIR-II imaging of MRSA infections. The use of sensitize rare-earth-doped nanoparticles and a near-infrared dye TPEO-820 enabled the controlled release of nitric oxide for effective disinfection of MRSA, as well as deep tissue imaging of MRSA infections.
ACTA BIOMATERIALIA
(2023)
Article
Multidisciplinary Sciences
Kang Li, Xingchen Duan, Zhiyong Jiang, Dan Ding, Yuncong Chen, Guo-Qiang Zhang, Zhipeng Liu
Summary: J-aggregation has been shown to be an effective strategy for developing fluorescent imaging agents in the NIR-II spectral region. However, designing suitable J-aggregates remains challenging. This study demonstrates the J-aggregation of a BODIPY dye with NIR-II emission and its application in lymph node imaging for fluorescence-guided surgery.
NATURE COMMUNICATIONS
(2021)
Article
Chemistry, Multidisciplinary
Deling Li, Hui Shi, Qingrong Qi, Baisong Chang, Yuanwen Jiang, Kun Qian, Xiudong Guan, Peng Kang, Ning Ma, Yuan Zhang, Zeyu Zhang, Xiaojing Shi, Chunrong Qu, Yilei Wu, Weiyu Chen, Hao Chen, Baowang Li, Liangpeng Chen, Ziyang Li, Shunchang Ma, Lingyun Xu, Yanrong Zhang, Jie Tian, Zhenhua Hu, Wang Jia, Zhen Cheng
Summary: Benzyl Violet 4B (BV-4B) is discovered as a novel solid-state dye in the NIR-II window and can be used for non-invasively monitoring the fate of medical devices in the human body. It can diagnose the rupture of BV-4B-coated silicone catheter and guide fluorescence-guided surgery for arteriovenous malformation with embolization glue.
Article
Chemistry, Medicinal
Jiafeng Li, Aiyan Ji, Meiling Lei, Liwen Xuan, Ruihu Song, Xin Feng, Haixia Lin, Hao Chen
Summary: Nowadays, the development focus of NIR-II dyes is on achieving longer absorption/emission wavelength and higher quantum yield. However, this often leads to larger molecular weight and poor druggability due to the extended pi conjugation system. In this study, a reduced pi conjugation system D-A probe (TQ-1006) was synthesized, showing comparable excellent imaging performance and a higher T/N ratio compared to its D-A-D counterpart (TQT-1048). A conjugated probe (TQ-RGD) demonstrated extra high contrast tumor imaging, further proving the excellent NIR-II biomedical imaging applications of D-A dyes. Overall, the D-A framework offers a promising approach for designing next-generation NIR-II fluorophores.
JOURNAL OF MEDICINAL CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Homan Kang, Md Shamim, Xiaoran Yin, Eeswar Adluru, Takeshi Fukuda, Shinya Yokomizo, Hyejin Chang, Seung Hun Park, Yanan Cui, Austin J. Moy, Satoshi Kashiwagi, Maged Henary, Hak Soo Choi
Summary: The strategy of structure-inherent tumor targeting with cyanine-based fluorophores has gained attention due to its targetability of tumor microenvironments without the need for additional targeting ligands. This study demonstrates that heptamethine-cyanine-based fluorophores not only possess targetability but also provide second near-infrared spectral window imaging capabilities. The new mechanism of structure-inherent tumor targeting suggests that immune cells derived from bone marrow or residing in tissues/tumors can be principal targets for cancer detection.
ADVANCED MATERIALS
(2022)
Article
Polymer Science
Yingbin Su, Yawei Miao, Yaowei Zhu, Wentao Zou, Bing Yu, Youqing Shen, Hailin Cong
Summary: In recent years, NIR-II fluorescence imaging technology has gradually replaced traditional visible light and NIR-I FI, showing great research value. By utilizing different thiophene derivatives in the design and synthesis of D-A polymers, the quantum yield was successfully increased.
Article
Medicine, Research & Experimental
Rui Cao, Renda Li, Hui Shi, Hongguang Liu, Zhen Cheng
Summary: A novel peptide called Herceptide was discovered to specifically target human epidermal growth factor receptor 2 (HER2). Herceptide was conjugated to the near-infrared fluorescent dye indocyanine green (ICG) to create the probe ICG-Herceptide. The probe showed high binding affinity to HER2 and was successfully used for imaging and localization of HER2-overexpressing tumors.
MOLECULAR PHARMACEUTICS
(2023)
Article
Materials Science, Multidisciplinary
Liao Zhang, Yutao Zhang, Weijie Chi, Chenxu Yan, Zijun Zhao, Xiaogang Liu, Wei-Hong Zhu, Zhiqian Guo
Summary: This study proposes a pi-conjugated crossbreeding dyad strategy to develop novel NIR-II dyes with small molecular weights, high stability, and good brightness, greatly expanding the high-resolution activatable in vivo imaging tools for intact tissues and living animals.
ACS MATERIALS LETTERS
(2022)
Review
Biochemistry & Molecular Biology
Qingluo Wang, Guoyu Xia, Jianmin Li, Longlong Yuan, Shujie Yu, Dingyang Li, Nan Yang, Zhongxiong Fan, Jinyao Li
Summary: Tumors are a major public health issue, and the application of near-infrared second region (NIR-II) optical imaging and nanomaterials in tumor diagnosis and treatment has garnered significant attention.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Nanoscience & Nanotechnology
Shuting Li, Zhaoyu Ma, Kai Zhang, Weiyun Zhang, Zhiyong Song, Wenjing Wang, Ximiao Yu, Heyou Han
Summary: The study successfully utilized acid-labile metal-organic frameworks as nano-carriers to efficiently mineralize hyaluronidase and encapsulate Ag2S nanodots, resulting in nanocomposites that maintained enzyme activity, altered in size for prolonged circulation, and effectively delivered cargo to the tumor site. This innovative strategy offers a promising approach for NIR-II multimodal imaging-guided PTT of deep tumors by decreasing nanoparticle size and degrading dense extracellular matrix.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Review
Biotechnology & Applied Microbiology
Songjiao Li, Dan Cheng, Longwei He, Lin Yuan
Summary: Cancer remains a major global health concern despite advances in diagnostic and therapeutic technologies. Near-infrared (NIR) fluorescence plays a crucial role in image-guided cancer surgeries due to its tissue penetration, minimal scattering, and low autofluorescence. This review provides insights into the principles of fluorescence molecular imaging and the applications of NIR image-guided surgery in biomedical research, while also discussing current challenges and future directions in surgical navigation using fluorescence imaging.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2021)
Article
Chemistry, Multidisciplinary
Hao Chen, Kangquan Shou, Si Chen, Chunrong Qu, Zhiming Wang, Lei Jiang, Mark Zhu, Bingbing Ding, Kun Qian, Aiyan Ji, Hongyue Lou, Ling Tong, Alexander Hsu, Yuebing Wang, Dean W. Felsher, Zhenhua Hu, Jie Tian, Zhen Cheng
Summary: The development of novel nanomaterials for disease theranostics, such as the pH-sensitive self-assembling cyclopeptide-dye SIMM1000, offers promising opportunities for high-resolution and sensitive imaging in living animals. Its smart properties in responding to changes in tumor microenvironments make it a valuable tool for molecular imaging and drug development.
ADVANCED MATERIALS
(2021)
Article
Engineering, Environmental
Xinping Zhang, Yuxin Guo, Xiaoyang Liu, Shun-Yu Wu, Ya-Xuan Zhu, Shao-Zhe Wang, Qiu-Yi Duan, Ke-Fei Xu, Zi-Heng Li, Xiao-Yu Zhu, Guang-Yu Pan, Fu-Gen Wu
Summary: This study develops a nanotrigger HCFT for simultaneous photodynamic therapy and light-triggered ferroptosis therapy. The nanotrigger can relieve tumor hypoxia, induce enhanced photodynamic reaction, and facilitate the continuation of Fenton reaction, ultimately leading to lethal ferroptosis in tumor cells.
CHEMICAL ENGINEERING JOURNAL
(2024)
Article
Engineering, Environmental
Olumide Bolarinwa Ayodele, Toyin Daniel Shittu, Olayinka S. Togunwa, Dan Yu, Zhen-Yu Tian
Summary: This study focused on the semihydrogenation of acetylene in an ethylene-rich stream using two alloyed Pt catalysts PtCu and PtCo. The PtCu catalyst showed higher activity and ethylene yield compared to PtCo due to its higher unoccupied Pt d-orbital density. This indicates that alloying Pt with Cu is more promising for industrial relevant SHA catalyst.
CHEMICAL ENGINEERING JOURNAL
(2024)
Article
Engineering, Environmental
Guowei Chen, Wen-Cheng Chen, Yaozu Su, Ruicheng Wang, Jia-Ming Jin, Hui Liang, Bingxue Tan, Dehua Hu, Shaomin Ji, Hao-Li Zhang, Yanping Huo, Yuguang Ma
Summary: This study proposes an intramolecular dual-locking design for organic luminescent materials, achieving high luminescence efficiency and performance for deep-blue organic light-emitting diodes. The material also exhibits unique mechanochromic luminescence behavior and strong fatigue resistance.
CHEMICAL ENGINEERING JOURNAL
(2024)
Article
Engineering, Environmental
Joren van Stee, Gregory Hermans, Jinu Joseph John, Koen Binnemans, Tom Van Gerven
Summary: This work presents a continuous solvent extraction method for the separation of cobalt and nickel in a millifluidic system using Cyphos IL 101 (C101) as the extractant. The optimal conditions for extraction performance and solvent properties were determined by investigating the effects of channel length, flow rate, and temperature. The performance of a developed manifold structure was compared to a single-channel system, and excellent separation results were achieved. The continuous separation process using the manifold structure resulted in high purity cobalt and nickel products.
CHEMICAL ENGINEERING JOURNAL
(2024)
Article
Engineering, Environmental
Yan Xu, Jingai Jiang, Xinyi Lv, Hui Li, Dongliang Yang, Wenjun Wang, Yanling Hu, Longcai Liu, Xiaochen Dong, Yu Cai
Summary: A programmed gas release nanoparticle was developed to address the challenges in treating diabetic infected wounds. It effectively removes drug-resistant pathogens and remodels the wound microenvironment using NO and H2S. The nanoparticle can eliminate bacteria and promote wound healing through antibacterial and anti-inflammatory effects.
CHEMICAL ENGINEERING JOURNAL
(2024)
Article
Engineering, Environmental
Tong Xia, Zhilin Xi, Lianquan Suo, Chen Wang
Summary: This study investigated a highly efficient coal dust suppressant with low initial viscosity and high adhesion-solidification properties. The results demonstrated that the dust suppressant formed a network of multiple hydrogen bonding cross-linking and achieved effective adhesion and solidification of coal dust through various chemical reactions.
CHEMICAL ENGINEERING JOURNAL
(2024)
Article
Engineering, Environmental
Jinzhi Cai, Zhenshan Li
Summary: A density functional theory-based rate equation was developed to predict the gas-solid reaction kinetics of CaO carbonation with CO2 in calcium looping. The negative activation energy of CaO carbonation close to equilibrium was accurately predicted through experimental validation.
CHEMICAL ENGINEERING JOURNAL
(2024)
Article
Engineering, Environmental
Jianxiong Chen, Fuhao Ren, Ningning Yin, Jie Mao
Summary: This study presents an economically efficient and easily implementable surface modification approach to enhance the high-temperature electrical insulation and energy storage performance of polymer dielectrics. The self-assembly of high-insulation-performance boron nitride nanosheets (BNNS) on the film surface through electrostatic interactions effectively impedes charge injection from electrodes while promoting charge dissipation and heat transfer.
CHEMICAL ENGINEERING JOURNAL
(2024)
Article
Engineering, Environmental
Zijian Li, Zhaohui Yang, Shao Wang, Hongxia Luo, Zhimin Xue, Zhenghui Liu, Tiancheng Mu
Summary: This study reports a strategy for upgrading polyester plastics into value-added chemicals using electrocatalytic methods. By inducing the targeted transfer of *OH species, polyethylene terephthalate was successfully upgraded into potassium diformate with high purity. This work not only develops an excellent electrocatalyst, but also provides guidance for the design of medium entropy metal oxides.
CHEMICAL ENGINEERING JOURNAL
(2024)
Article
Engineering, Environmental
Navneet Singh Shekhawat, Surendra Kumar Patra, Ashok Kumar Patra, Bamaprasad Bag
Summary: This study primarily focuses on developing a sulphur dyeing process at room temperature using bacterial Lysate, which is environmentally friendly, energy and cost effective, and sustainable. The process shows promising improvements in dye uptake and fastness properties.
CHEMICAL ENGINEERING JOURNAL
(2024)
Article
Engineering, Environmental
Dengjia Shen, Hongyang Ma, Madani Khan, Benjamin S. Hsiao
Summary: This study developed cationic PVC nanofibrous membranes with high filtration and adsorption capability for the removal of bacteria and hexavalent chromium ions from wastewater. The membranes demonstrated remarkable performance in terms of filtration efficiency and maximum adsorption capacity. Additionally, modified nanofibrous membranes were produced using recycled materials and showed excellent retention rates in dynamic adsorption processes.
CHEMICAL ENGINEERING JOURNAL
(2024)
Article
Engineering, Environmental
Xiaoyan Wang, Zhikun Wang, Ben Jia, Chunling Li, Shuangqing Sun, Songqing Hu
Summary: Inspired by photosystem II, self-supported Fe-doped NiCoP nanowire arrays modified with carboxylate were constructed to boost industrial-level overall water splitting by employing the concerted proton-coupled electron transfer mechanism. The introduction of Fe and carboxyl ligand led to improved catalytic activity for HER and OER, and NCFCP@NF exhibited long-term durability for overall water splitting.
CHEMICAL ENGINEERING JOURNAL
(2024)
Article
Engineering, Environmental
Pengyao Yu, Ge Yang, Yongming Chai, Lubomira Tosheva, Chunzheng Wang, Heqing Jiang, Chenguang Liu, Hailing Guo
Summary: Thin LTA zeolite membranes were prepared through secondary growth of nano LTA seeds in a highly reactive gel, resulting in membranes with superior permeability and selectivity in gas separation applications.
CHEMICAL ENGINEERING JOURNAL
(2024)
Article
Engineering, Environmental
Baiqin Zhou, Huiping Li, Ziyu Wang, Hui Huang, Yujun Wang, Ruichun Yang, Ranran Huo, Xiaoyan Xu, Ting Zhou, Xiaochen Dong
Summary: The use of machine learning to predict the performance of specific adsorbents in phosphate adsorption shows great promise in saving time and revealing underlying mechanisms. However, the small size of the dataset and insufficient detailed information limits the model training process and the accuracy of results. To address this, the study employs a fuzzing strategy that replaces detailed numeric information with descriptive text messages on the physiochemical properties of adsorbents. This strategy allows the recovery of discarded samples with limited information, leading to accurate prediction of adsorption amount, capacity, and kinetics. The study also finds that phosphate uptake by adsorbents is generally through physisorption, with some involvement of chemisorption. The framework established in this study provides a practical approach for quickly predicting phosphate adsorption performance in urgent scenarios, using easily accessible information.
CHEMICAL ENGINEERING JOURNAL
(2024)
Article
Engineering, Environmental
Paula Alejandra Lamprea Pineda, Joren Bruneel, Kristof Demeestere, Lisa Deraedt, Tex Goetschalckx, Herman Van Langenhove, Christophe Walgraeve
Summary: This study evaluates the use of four esterified fatty acids and three vegetable oils as absorption liquids for hydrophobic VOCs. The experimental results show that isopropyl myristate is the most efficient liquid for absorbing the target VOCs.
CHEMICAL ENGINEERING JOURNAL
(2024)