Genetically modified rodent models of SCA17

Large Polyglutamine Repeats Cause Muscle Degeneration in SCA17 Mice

(2015) Shanshan Huang et al.   Cell Reports

Age-Dependent Decrease in Chaperone Activity Impairs MANF Expression, Leading to Purkinje Cell Degeneration in Inducible SCA17 Mice

(2014) Su Yang et al.   NEURON

A Novel Transgenic Rat Model for Spinocerebellar Ataxia Type 17 Recapitulates Neuropathological Changes and Supplies In Vivo Imaging Biomarkers

(2013) A. Kelp et al.   JOURNAL OF NEUROSCIENCE

Sex-Dependent Behavioral Functions of the Purkinje Cell-Specific Gαi/o Binding Protein, Pcp2(L7)

(2012) James C. Walton et al.   CEREBELLUM

Neuronal expression of TATA box-binding protein containing expanded polyglutamine in knock-in mice reduces chaperone protein response by impairing the function of nuclear factor-Y transcription factor

(2011) Shanshan Huang et al.   BRAIN

Neuroprotective effects of granulocyte-colony stimulating factor in a novel transgenic mouse model of SCA17

(2011) Ya-Chin Chang et al.   JOURNAL OF NEUROCHEMISTRY

Autosomal dominant cerebellar ataxia type I: A review of the phenotypic and genotypic characteristics

(2011) Nathaniel Whaley et al.   Orphanet Journal of Rare Diseases

A rotarod test for evaluation of motor skill learning

(2010) Hiromi Shiotsuki et al.   JOURNAL OF NEUROSCIENCE METHODS

Native Functions of the Androgen Receptor Are Essential to Pathogenesis in a Drosophila Model of Spinobulbar Muscular Atrophy

(2010) Natalia B. Nedelsky et al.   NEURON

Tests to assess motor phenotype in mice: a user's guide

(2009) Simon P. Brooks et al.   NATURE REVIEWS NEUROSCIENCE

Spinocerebellar ataxia 17 (SCA17) and Huntington’s disease-like 4 (HDL4)

(2008) Giovanni Stevanin et al.   CEREBELLUM

Polyglutamine Expansion Reduces the Association of TATA-binding Protein with DNA and Induces DNA Binding-independent Neurotoxicity

(2008) Meyer J. Friedman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY