In vivo analysis of cerebellar Purkinje cell activity in SCA2 transgenic mouse model

In vivo analysis of Purkinje cell firing properties during postnatal mouse development

(2015) Marife Arancillo et al.   JOURNAL OF NEUROPHYSIOLOGY

Spinocerebellar Ataxia Type 6 Protein Aggregates Cause Deficits in Motor Learning and Cerebellar Plasticity

(2015) M. D. Mark et al.   JOURNAL OF NEUROSCIENCE

Neuronal Atrophy Early in Degenerative Ataxia Is a Compensatory Mechanism to Regulate Membrane Excitability

(2015) J. M. Dell'Orco et al.   JOURNAL OF NEUROSCIENCE

Riluzole in patients with hereditary cerebellar ataxia: a randomised, double-blind, placebo-controlled trial

(2015) Silvia Romano et al.   LANCET NEUROLOGY

Disturbed calcium signaling in spinocerebellar ataxias and Alzheimer's disease

(2015) Polina Egorova et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Motor Learning and the Cerebellum

(2015) Chris I. De Zeeuw et al.   Cold Spring Harbor Perspectives in Biology

Cerebellar modules operate at different frequencies

(2014) Haibo Zhou et al.   eLife

Selective Positive Modulator of Calcium-Activated Potassium Channels Exerts Beneficial Effects in a Mouse Model of Spinocerebellar Ataxia Type 2

(2012) Adebimpe W. Kasumu et al.   CHEMISTRY & BIOLOGY

Changes in Purkinje cell firing and gene expression precede behavioral pathology in a mouse model of SCA2

(2012) S. T. Hansen et al.   HUMAN MOLECULAR GENETICS

Chronic Suppression of Inositol 1,4,5-Triphosphate Receptor-Mediated Calcium Signaling in Cerebellar Purkinje Cells Alleviates Pathological Phenotype in Spinocerebellar Ataxia 2 Mice

(2012) A. W. Kasumu et al.   JOURNAL OF NEUROSCIENCE

Cerebellar Ataxia by Enhanced CaV2.1 Currents Is Alleviated by Ca2+-Dependent K+-Channel Activators in Cacna1aS218L Mutant Mice

(2012) Z. Gao et al.   JOURNAL OF NEUROSCIENCE

Genetically engineered mouse models of the trinucleotide-repeat spinocerebellar ataxias

(2011) Melissa A.C. Ingram et al.   BRAIN RESEARCH BULLETIN

Early Changes in Cerebellar Physiology Accompany Motor Dysfunction in the Polyglutamine Disease Spinocerebellar Ataxia Type 3

(2011) V. G. Shakkottai et al.   JOURNAL OF NEUROSCIENCE

Abnormalities in the Climbing Fiber-Purkinje Cell Circuitry Contribute to Neuronal Dysfunction in ATXN1[82Q] Mice

(2011) J. A. Barnes et al.   JOURNAL OF NEUROSCIENCE

Purkinje neuron synchrony elicits time-locked spiking in the cerebellar nuclei

(2011) Abigail L. Person et al.   NATURE

Spatiotemporal firing patterns in the cerebellum

(2011) Chris I. De Zeeuw et al.   NATURE REVIEWS NEUROSCIENCE

Role of Inositol 1,4,5-Trishosphate Receptors in Pathogenesis of Huntington’s Disease and Spinocerebellar Ataxias

(2011) Ilya Bezprozvanny   NEUROCHEMICAL RESEARCH

Deranged Calcium Signaling in Purkinje Cells and Pathogenesis in Spinocerebellar Ataxia 2 (SCA2) and Other Ataxias

(2010) Adebimpe Kasumu et al.   CEREBELLUM

Pharmacological Modulation of the Gating Properties of Small Conductance Ca2+-Activated K+ Channels Alters the Firing Pattern of Dopamine Neurons In Vivo

(2010) Kjartan F. Herrik et al.   JOURNAL OF NEUROPHYSIOLOGY

The Therapeutic Mode of Action of 4-Aminopyridine in Cerebellar Ataxia

(2010) K. Alvina et al.   JOURNAL OF NEUROSCIENCE

KCa Channels as Therapeutic Targets in Episodic Ataxia Type-2

(2010) K. Alvina et al.   JOURNAL OF NEUROSCIENCE

Riluzole in cerebellar ataxia: A randomized, double-blind, placebo-controlled pilot trial

(2010) G. Ristori et al.   NEUROLOGY

Disruption of the olivo-cerebellar circuit by Purkinje neuron-specific ablation of BK channels

(2010) X. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cellular and Molecular Pathways Triggering Neurodegeneration in the Spinocerebellar Ataxias

(2009) Antoni Matilla-Dueñas et al.   CEREBELLUM

Emerging pathogenic pathways in the spinocerebellar ataxias

(2009) Kerri M Carlson et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Deranged Calcium Signaling and Neurodegeneration in Spinocerebellar Ataxia Type 2

(2009) J. Liu et al.   JOURNAL OF NEUROSCIENCE

Purkinje-Cell-Restricted Restoration of Kv3.3 Function Restores Complex Spikes and Rescues Motor Coordination in Kcnc3 Mutants

(2008) E. C. Hurlock et al.   JOURNAL OF NEUROSCIENCE

High-Frequency Organization and Synchrony of Activity in the Purkinje Cell Layer of the Cerebellum

(2008) Camille de Solages et al.   NEURON