The antiepileptic and ictogenic effects of optogenetic neurostimulation of PV-expressing interneurons

Interneuron activity leads to initiation of low-voltage fast-onset seizures

(2015) Zahra Shiri et al.   ANNALS OF NEUROLOGY

Selective activation of parvalbumin- or somatostatin-expressing interneurons triggers epileptic seizurelike activity in mouse medial entorhinal cortex

(2015) Latefa Yekhlef et al.   JOURNAL OF NEUROPHYSIOLOGY

Synchronous Inhibitory Potentials Precede Seizure-Like Events in Acute Models of Focal Limbic Seizures

(2015) L. Uva et al.   JOURNAL OF NEUROSCIENCE

Microcircuits and their interactions in epilepsy: is the focus out of focus?

(2015) Jeanne T Paz et al.   NATURE NEUROSCIENCE

Beyond the hammer and the scalpel: selective circuit control for the epilepsies

(2015) Esther Krook-Magnuson et al.   NATURE NEUROSCIENCE

Optogenetics and Epilepsy: Past, Present and Future

(2015) Jeanne T. Paz et al.   Epilepsy Currents

Seizure Suppression by High Frequency Optogenetic Stimulation Using In Vitro and In Vivo Animal Models of Epilepsy

(2014) Chia-Chu Chiang et al.   Brain Stimulation

WONOEP appraisal: Optogenetic tools to suppress seizures and explore the mechanisms of epileptogenesis

(2014) Laura Mantoan Ritter et al.   EPILEPSIA

Muscarinic excitation of parvalbumin-positive interneurons contributes to the severity of pilocarpine-induced seizures

(2014) Feng Yi et al.   EPILEPSIA

Global Optogenetic Activation of Inhibitory Interneurons during Epileptiform Activity

(2014) M. Ledri et al.   JOURNAL OF NEUROSCIENCE

Direct excitation of parvalbumin-positive interneurons by M1muscarinic acetylcholine receptors: roles in cellular excitability, inhibitory transmission and cognition

(2014) Feng Yi et al.   JOURNAL OF PHYSIOLOGY-LONDON

Electrical brain stimulation for epilepsy

(2014) Robert S. Fisher et al.   Nature Reviews Neurology

Optogenetic inhibition of chemically induced hypersynchronized bursting in mice

(2014) Fredrik Berglind et al.   NEUROBIOLOGY OF DISEASE

Closed-loop Neurostimulation: The Clinical Experience

(2014) Felice T. Sun et al.   Neurotherapeutics

Neurostimulation in the treatment of epilepsy

(2013) Gregory K. Bergey   EXPERIMENTAL NEUROLOGY

New insights into the classification and nomenclature of cortical GABAergic interneurons

(2013) Javier DeFelipe et al.   NATURE REVIEWS NEUROSCIENCE

Hippocampal neuron firing and local field potentials in the in vitro 4-aminopyridine epilepsy model

(2012) Alfredo Gonzalez-Sulser et al.   JOURNAL OF NEUROPHYSIOLOGY

Closed-loop optogenetic control of thalamus as a tool for interrupting seizures after cortical injury

(2012) Jeanne T Paz et al.   NATURE NEUROSCIENCE

Optogenetic investigation of neural circuits underlying brain disease in animal models

(2012) Kay M. Tye et al.   NATURE REVIEWS NEUROSCIENCE

How inhibition influences seizure propagation

(2012) Andrew J. Trevelyan et al.   NEUROPHARMACOLOGY

Therapeutic devices for epilepsy

(2011) Robert S. Fisher   ANNALS OF NEUROLOGY

The Development and Application of Optogenetics

(2011) Lief Fenno et al.   Annual Review of Neuroscience

Optogenetics in Neural Systems

(2011) Ofer Yizhar et al.   NEURON

Drug-Resistant Epilepsy

(2011) Patrick Kwan et al.   NEW ENGLAND JOURNAL OF MEDICINE

GABAergic synchronization in the limbic system and its role in the generation of epileptiform activity

(2011) Massimo Avoli et al.   PROGRESS IN NEUROBIOLOGY

Three groups of interneurons account for nearly 100% of neocortical GABAergic neurons

(2010) Bernardo Rudy et al.   Developmental Neurobiology

Response Features of Parvalbumin-Expressing Interneurons Suggest Precise Roles for Subtypes of Inhibition in Visual Cortex

(2010) Caroline A. Runyan et al.   NEURON

Reevaluating the mechanisms of focal ictogenesis: The role of low-voltage fast activity

(2009) Marco de Curtis et al.   EPILEPSIA

Parvalbumin neurons and gamma rhythms enhance cortical circuit performance

(2009) Vikaas S. Sohal et al.   NATURE

Parvalbumin neurons in the forebrain as revealed by parvalbumin-Cre transgenic mice

(2009) Chiyoko Tanahira et al.   NEUROSCIENCE RESEARCH

Fast activity at seizure onset is mediated by inhibitory circuits in the entorhinal cortex in vitro

(2008) Vadym Gnatkovsky et al.   ANNALS OF NEUROLOGY