n-Propyl-4-aza-1-azoniabicyclo[2.2.2]octane chloride-SBA-1 5 (SBA-DABCO) as basic mesoporous catalyst for the synthesis of 1,4-dihydropyridine hetrocyclic compounds

Regarding the green chemistry's goals, the development of mesoporous silica materials as attractive candidates in the search for supporting of catalysts is currently a subject of increasing interest. Therefore, in the present research n-propyl-4-aza-1-azoniabicyclo[2.2.2]octane chloride-SBA-15 (SBA DABCO) was used as a basic catalyst for the synthesis of 1,4-dihydropyridine (DHP) derivatives from one pot, three-component condensation of arofnatic aldehydes, ammonium acetate and ethylacetoacetate under solvent-free at 80 degrees C. This method offers several advantages, including high yield, short reaction time, simple work-up procedure, ease of separation and recyclability of the catalyst, as well as the ability to tolerate a wide variety of substitutions in the reagents. (C) 2015 Elsevier B.V. All rights reserved.