Ultrasensitive HPLC-MS Quantification of S-(2-Succino) Cysteine Based on Ethanol/Acetyl Chloride Derivatization in Fumarate Accumulation Cells

Succination of Protein Thiols in Human Brain Aging

(2020) Mariona Jové et al.   Frontiers in Aging Neuroscience

An Oncometabolite Isomer Rapidly Induces a Pathophysiological Protein Modification

(2020) Sarah E. Bergholtz et al.   ACS Chemical Biology

Succination inactivates gasdermin D and blocks pyroptosis

(2020) Fiachra Humphries et al.   SCIENCE

SDHA gain-of-function engages inflammatory mitochondrial retrograde signaling via KEAP1–Nrf2

(2019) Anne-Valérie Burgener et al.   NATURE IMMUNOLOGY

Glutaminolysis and Fumarate Accumulation Integrate Immunometabolic and Epigenetic Programs in Trained Immunity

(2016) Rob J.W. Arts et al.   Cell Metabolism

LPS stimulates IgM production in vivo without help from non-B cells

(2016) Mingfang Lu et al.   Innate Immunity

Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition

(2016) Marco Sciacovelli et al.   NATURE

Dimethyl fumarate treatment induces adaptive and innate immune modulation independent of Nrf2

(2016) Ulf Schulze-Topphoff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystallographic insight-guided nanoarchitectonics and conductivity modulation of an n-type organic semiconductor through peptide conjugation

(2015) M. Pandeeswar et al.   CHEMICAL COMMUNICATIONS

Identification of Fumarate Hydratase Inhibitors with Nutrient-Dependent Cytotoxicity

(2015) Toshifumi Takeuchi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The succinated proteome

(2013) Eric D. Merkley et al.   MASS SPECTROMETRY REVIEWS

The Proto-oncometabolite Fumarate Binds Glutathione to Amplify ROS-Dependent Signaling

(2013) Lucas B. Sullivan et al.   MOLECULAR CELL

Inhibition of Mitochondrial Aconitase by Succination in Fumarate Hydratase Deficiency

(2013) Nicola Ternette et al.   Cell Reports

Renal Cyst Formation in Fh1-Deficient Mice Is Independent of the Hif/Phd Pathway: Roles for Fumarate in KEAP1 Succination and Nrf2 Signaling

(2011) Julie Adam et al.   CANCER CELL

Succination of proteins in diabetes

(2010) Norma Frizzell et al.   FREE RADICAL RESEARCH

Succination of Thiol Groups in Adipose Tissue Proteins in Diabetes

(2009) Norma Frizzell et al.   JOURNAL OF BIOLOGICAL CHEMISTRY