Article
Clinical Neurology
Mario Alberto Battaglia, Daiana Bezzini, Isabella Cecchini, Cinzia Cordioli, Francesca Fiorentino, Tommaso Manacorda, Mihaela Nica, Michela Ponzio, Daniela Ritrovato, Chiara Vassallo, Francesco Patti
Summary: This study estimates the burden and cost of illness of multiple sclerosis (MS) in Italy in 2019 from a societal perspective. The results show a significant impact of the disease on patients' daily activities and work, increasing with disability. Fatigue is identified as a major burden. The overall cost of the disease in Italy is estimated at 4.8 billion euros.
JOURNAL OF NEUROLOGY
(2022)
Article
Infectious Diseases
Catherine Weil-Olivier, Muhamed-Kheir Taha, Corinne Emery, Stephane Bouee, Ekkehard Beck, Emmanuel Aris, Veronique Loncle-Provot, Gaelle Nachbaur, Celine Pribil
Summary: In this study, the healthcare claims database in France was used to examine the costs incurred by patients hospitalized for invasive meningococcal disease (IMD) over a 6-year period. The economic burden of IMD was found to be high, driven primarily by the long-term costs associated with managing sequelae.
INFECTIOUS DISEASES AND THERAPY
(2021)
Article
Public, Environmental & Occupational Health
J. Skov Bundgaard, U. M. Mogensen, S. Christensen, U. Ploug, R. Rorth, R. Ibsen, J. Kjellberg, L. Kober
Summary: Heart failure patients have a wide range of health costs, and individual management differences can lead to significant cost heterogeneity. There are noticeable differences between high-cost and low-cost groups, with younger age, hospitalization, and comorbidities being potential factors associated with higher costs.
Article
Medicine, General & Internal
Christoffer Bugge, Odd Terje Brustugun, Erik Magnus Saether, Ivar Sonbo Kristiansen
Summary: Valid estimates of cancer treatment costs are important for priority setting, with higher lifetime costs identified for cancers with a 5-year relative survival between 50% and 70%. Future cancer costs are highly dependent on future cancer incidence, changes in death risk, and cancer-specific unit costs. Gender- and cancer-specific estimates of treatment costs are important for assessing equity of care and understanding resource consumption.
Article
Pediatrics
Sarah Kristine Norgaard, Nadja Hawwa Vissing, Bo Lund Chawes, Jakob Stokholm, Klaus Bonnelykke, Hans Bisgaard
Summary: Childhood illness imposes a significant economic burden on society. A study on 700 children investigated the economic impact of illness in the first three years of life, finding that factors such as fish-oil supplementation during pregnancy, gestational age, and birth weight were associated with reduced costs, while cesarean delivery was associated with higher costs. Targeting perinatal risk factors may help reduce the financial burden of common childhood illnesses.
Article
Pediatrics
Chantal Grandjean, Marie-Helene Perez, Anne-Sylvie Ramelet, OCToPuS Consortium
Summary: This study aimed to describe the prevalence of chronic critically ill (CCI) children in the pediatric intensive care unit (PICU), compare their clinical characteristics and ICU resource use with non-CCI children, and identify associated risk factors of CCI. The results confirm the clinical vulnerability and the complexity of care of CCI children as defined in the study, highlighting the need for early identification and adequate staffing to provide appropriate and good quality care.
FRONTIERS IN PEDIATRICS
(2023)
Article
Public, Environmental & Occupational Health
Zhuo Zeng, Ning Li, Ling Yang, Xue Feng, Fangqing Zuo, Gaoxing Luo, Yizhi Peng, Zhiqiang Yuan
Summary: The study analyzed the hospitalization costs of severe burn inpatients in Southwest China. It found that the average total cost per patient was 212,755.45 CNY, with medical consumables being the largest portion of the costs. The study suggests the need for an effective burn prevention program, shorter hospital stays, and promoting wound healing to reduce the medical costs of severe burn inpatients.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Medicine, General & Internal
Jeongsoo Kim, Michael A. Jacobs, Susanne Schmidt, Bradley B. Brimhall, Camerino I. Salazar, Chen-Pin Wang, Zhu Wang, Laura S. Manuel, Paul Damien, Paula K. Shireman
Summary: This study analyzed the cost savings of quality improvement projects using different cost measures and insurance types. The results showed higher complications rates and costs for Medicare and Medicaid/Uninsured patients compared to Private patients. It also highlighted the importance of using variable costs rather than total costs to accurately estimate the potential cost savings of quality improvement interventions.
Article
Geriatrics & Gerontology
Alejandro Alvarez-Bustos, Beatriz Rodriguez-Sanchez, Jose A. Carnicero-Carreno, Walter Sepulveda-Loyola, Francisco J. Garcia-Garcia, Leocadio Rodriguez-Manas
Summary: The study found that frailty and sarcopenia can lead to higher risk of hospitalization in older adults and increase healthcare expenditures.
Article
Health Care Sciences & Services
Ahmed Alghamdi, Eman Algarni, Bander Balkhi, Abdulaziz Altowaijri, Abdulaziz Alhossan
Summary: This study estimated the healthcare expenditures associated with heart failure in Saudi Arabia, revealing a high economic burden primarily driven by hospitalization costs, medication, and diagnostics costs. Decision makers in Saudi Arabia should focus on strategies to prevent frequent hospitalizations and improve heart failure management and patient outcomes.
Article
Mathematics
Shujie Zou, Chiawei Chu, Ning Shen, Jia Ren
Summary: This paper introduces a hybrid machine learning algorithm for predicting healthcare cost by first learning the isolated characteristic variables using network structure learning algorithms and then training regression algorithms. Experimental results show that the proposed scheme can achieve similar or higher prediction accuracy with a reduced amount of data, compared to popular single machine learning algorithms.
Article
Economics
Tu My To, Jamie T. Ta, Anisha M. Patel, Stella Arndorfer, Ibrahim M. Abbass, Rita Gandhy
Summary: This study quantified healthcare resource utilization and costs for individuals with late-onset Huntington's disease (LoHD), comparing them with adult-onset HD (AoHD) and non-HD controls. The results showed that LoHD patients had significantly higher healthcare burden and costs than non-HD controls, similar to AoHD patients. This highlights the significant healthcare burden associated with LoHD.
JOURNAL OF MEDICAL ECONOMICS
(2023)
Article
Orthopedics
Marie Schild, Ulrike Mueller, Ursula von Schenck, Sigurd Prieur, Robert Miller
Summary: A retrospective cohort analysis of German OA patients revealed that those with chronic pain have higher healthcare resource utilization and costs. Better prevention and treatment of OA are needed to reduce the disease burden experienced by patients.
BMC MUSCULOSKELETAL DISORDERS
(2021)
Article
Medicine, General & Internal
Oliver A. Nascimento, Jose Eduardo Delfini Cancado, Mariana Rodrigues Gazzotti, Felipe Moraes dos Santos, Luciana Tarbes Mattana Saturnino, Danielle Oliveira da Silva, Ana Luisa Bessa Bacellar Gomes, Karynna Pimentel Viana, Rafael Alfonso-Cristancho, Claudia Soares Rodrigues
Summary: A retrospective cohort study was conducted to assess healthcare resource utilization and costs of patients with asthma in the Brazilian Supplementary Healthcare System. The study focused on hospitalization data and found that the emergency visit rate was 0.34 per person-year, while the hospital admission rate was 0.04 per person-year. The mean length of hospital stay was 8.82 days, with an average cost per episode of 3178 Brazilian Real (BRL). The study also revealed that ICU-dependent asthma exacerbations could cost up to 75,000 BRL in the Supplementary Healthcare System. Improving disease control could help alleviate the burden on both the healthcare system and patients.
Article
Public, Environmental & Occupational Health
Valentina Ignatova, Kostadin Kostadinov, Evguenia Vassileva, Naira Muradyan, Georgi Stefanov, Georgi Iskrov, Rumen Stefanov
Summary: This study estimated the annual costs of MG patients in Bulgaria from a societal perspective and found that direct healthcare costs slightly outweighed indirect costs, with drug costs having the biggest impact. Severe generalized disease, disease crises, and recurrent infections were identified as significant cost drivers. The reliance on family members as informal caregivers among Bulgarian MG patients was common, likely due to the lack of access to appropriate social services. Further research and targeted health policies are needed to meet the needs of these patients.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Health Care Sciences & Services
Qais Alefan, Rawan Amairi, Shoroq Tawalbeh
BMC HEALTH SERVICES RESEARCH
(2018)
Article
Health Care Sciences & Services
Shoroq M. Altawalbeh, Rawan Abu- Su'Ud, Qais Alefan, Suleiman Mohammad Momany, Sandra L. Kane-Gill
EXPERT REVIEW OF PHARMACOECONOMICS & OUTCOMES RESEARCH
(2019)
Article
Medicine, General & Internal
Qais Alefan, Dima Huwari, Osama Y. Alshogran, Mohamad Jarrah
PATIENT PREFERENCE AND ADHERENCE
(2019)
Article
Medicine, General & Internal
Qais Alefan, Eman T. Al-Issa, Karem H. Alzoubi, Hanan M. Hammouri
Article
Health Care Sciences & Services
Qais Alefan, Esra'a Hamdouni, Hamza Alhamad, Tareq Mukattash, Karen Rascati
Summary: The study identified three main barriers to the implementation of pharmacoeconomics in Jordan, related to the nature of the decision-making process, the lack of pharmacoeconomic data, and inadequate knowledge about pharmacoeconomics. These barriers restrict the current use and impact of pharmacoeconomic evaluations in Jordanian healthcare decision-making.
EXPERT REVIEW OF PHARMACOECONOMICS & OUTCOMES RESEARCH
(2021)
Article
Pharmacology & Pharmacy
Rebecca Erker, Qais Alefan, Donna Goodridge, Alex Crawley, Norma Rabbitskin, Shirley Bighead, David Blackburn
Summary: The pharmacist intervention successfully improved medication adherence among patients with chronic conditions, leading to better self-management behaviors. The healthcare team found the pharmacist's support beneficial, and patients valued having a trusted pharmacist to rely on.
JOURNAL OF THE AMERICAN PHARMACISTS ASSOCIATION
(2021)
Article
Allergy
Mu'min Billah M. Shdaifat, Rawand A. Khasawneh, Qais Alefan
Summary: Pharmacist-led telemedicine counseling shows significant improvements in clinical and economic outcomes for pediatric asthma patients, reducing parental loss of wages and economic burden. The approach also leads to overall improvement in quality of life and patient satisfaction with telemedicine sessions.
Review
Pharmacology & Pharmacy
Qais Alefan, Vishnu Meghana Cheekireddy, David Blackburn
Summary: This study aimed to examine the relationship between cost-related nonadherence (CRNA) and general medication nonadherence, and found that the risk factor patterns identified in CRNA studies were consistent with general nonadherence. However, there were differences in the association between poor health and nonadherence between CRNA studies and general nonadherence studies.
JOURNAL OF THE AMERICAN PHARMACISTS ASSOCIATION
(2022)
Article
Pharmacology & Pharmacy
Qais Alefan, Shenzhen Yao, Jeffrey G. Taylor, Lisa M. Lix, Dean Eurich, Niteesh Choudhry, David F. Blackburn
Summary: The study reveals a strong association between adverse effects and early drug discontinuation, but this link is influenced by various external factors such as age, gender, health condition, perceived importance of medication, and expectation of adverse effects before starting treatment.
JOURNAL OF THE AMERICAN PHARMACISTS ASSOCIATION
(2022)
Article
Economics
Eman A. Hammad, Ibrahim Alabbadi, Fardos Taissir, Malek Hajjwi, Nathir M. Obeidat, Qais Alefan, Rimal Mousa
Summary: This study aimed to benchmark the unit costs of hospital services in public providers in Jordan and analyze the factors affecting unit costs. The study found variations in unit costs across different service types and institutions, highlighting the importance of understanding these differences for cost control and future research.
HEALTH ECONOMICS REVIEW
(2022)
Article
Pharmacology & Pharmacy
Shoroq M. Altawalbeh, Basima A. Almomani, Qais Alefan, Suleiman Mohammad Momany, Qusai Y. Al-Share
Summary: This study found that higher intensity of COPD treatment-related adverse effects has a negative influence on HRQoL in COPD patients. Anticholinergic drug effects are of concern in the COPD adult population.
INTERNATIONAL JOURNAL OF PHARMACY PRACTICE
(2022)
Article
Oncology
Qais Alefan, Alaa Saadeh, Rami J. Yaghan
BREAST CANCER MANAGEMENT
(2020)
Article
Pharmacology & Pharmacy
Qais Alefan, Somayya Alshareef, Samah Al-Shatnawi
PHARMACY PRACTICE-GRANADA
(2019)
Article
Health Care Sciences & Services
Tareq L. Mukattash, Shada Alkhaldi, Qais Alefan, Anan S. Jarab, Rana K. Abu Farha, Ahmad Al-Azayzih
JOURNAL OF PHARMACEUTICAL HEALTH SERVICES RESEARCH
(2018)
Article
Health Care Sciences & Services
Ricardo R. A. Fernandes, Bruno M. Barros, Milene R. da Costa, Carlos A. S. Magliano, Bernardo R. Tura, Quenia Cristina D. Morais, Marisa Santos
Summary: The use of nirmatrelvir/ritonavir in the treatment of COVID-19 in a vaccinated population was cost-effective only for immunosuppressed individuals and people over 60 years of age, while it showed a higher cost-effectiveness ratio for other groups.
VALUE IN HEALTH REGIONAL ISSUES
(2024)
Article
Health Care Sciences & Services
Abyan Irzaldy, Rema Gvamichava, Tina Beruchashvili, Lela Sturua, Nicolien T. van Ravesteyn, Harry J. de Koning, Eveline A. M. Heijnsdijk
Summary: This study used the MISCAN-Breast model to evaluate 736 breast cancer mammography screening strategies. The results showed that strategies combining mammography and clinical breast examination (CBE) had higher costs and minimal differences in outcomes compared to mammography-only strategies. The current strategy in Georgia, biennial mammography screening from 40 to 70 years with CBE, is close to the optimal strategy but requires high additional costs. The optimal strategy for Georgia would be triennial mammography-only screening from 45 to 66 years.
VALUE IN HEALTH REGIONAL ISSUES
(2024)
Article
Health Care Sciences & Services
Finn McGuire, Sakshi Mohan, Simon Walker, Juliet Nabyonga-Orem, Freddie Ssengooba, Edward Kataika, Paul Revill
Summary: Undertaking value assessments for health system inputs is crucial for allocative efficiency, especially in low- and middle-income countries. However, there are methodological challenges in applying current economic evaluation techniques to health system input investments. A comprehensive standardized framework for value assessments does not exist, and the literature largely ignores these methodological issues, potentially leading to inaccurate cost-effectiveness assessments.
VALUE IN HEALTH REGIONAL ISSUES
(2024)
Article
Health Care Sciences & Services
Joanna Augustynska, Monika Lichodziejewska-Niemierko, Beata Naumnik, Michal Seweryn, Agnieszka Leszczynska, Ryszard Gellert, Bengt Lindholm, Jacek Lange, Justyna Kopel
Summary: This study reviewed recent scientific research on the use of remote patient monitoring (RPM) in patients treated with automated peritoneal dialysis (APD), and assessed the clinical implications and potential economic value of introducing such a system into practice in Poland based on extracted relevant data. The results showed that APD with RPM significantly reduced hospitalization frequency and length, as well as APD technique failure and death.
VALUE IN HEALTH REGIONAL ISSUES
(2024)
Article
Health Care Sciences & Services
Andro Koren, Luciana Koren, Robert Marcec, Darko Marcinko, Robert Likic
Summary: Benzodiazepines are widely prescribed in Croatia for various conditions, but long-term use is associated with negative side effects.
VALUE IN HEALTH REGIONAL ISSUES
(2024)
Article
Health Care Sciences & Services
Yaneth Gil-Rojas, Pieralessandro Lasalvia, Victor Saenz, Oscar Virgueez, Maria P. Pena, Camilo Castaneda-Cardona, Maria E. Laucho-Contreras, Andres L. Gonzalez, Carmen Y. Garcia-Nuncira, Diego Rosselli
Summary: This study aimed to describe the clinical characteristics and direct medical costs associated with asthma treatment in Colombia patients. The results showed that medication use and outpatient visits were the main drivers of costs, and costs were higher in severe cases and in the adult/elderly population.
VALUE IN HEALTH REGIONAL ISSUES
(2024)
Article
Health Care Sciences & Services
Mohd Redhuan Dzulkipli, Asrul Akmal Shafie, Siti Noorsuriani Maon, Azuana Ramli, Abdul Haniff Mohammad Yahaya, See Wan Ho, Nor Ilham Ainaa Muhsin, Azmi Nor Mohd Farez Ahmat
Summary: This study aimed to determine the willingness to pay (WTP) for innovative oncology medicines among Malaysians. The results showed that more than half of the respondents were willing to pay for innovative oncology medicines, indicating the potential for collaborative funding mechanisms and appropriate financial screening to expedite access to these medicines in Malaysia.
VALUE IN HEALTH REGIONAL ISSUES
(2024)
Article
Health Care Sciences & Services
Leonard Lee, Hansoo Kim
Summary: This study investigates the impact of price control measures on statin prices and government expenditure in Australia. The results show that statin prices decreased under price control measures, leading to a reduction in government expenditure. The effects of price disclosure on market share suggest that industry-prompted price reductions may be driven by market share loss.
VALUE IN HEALTH REGIONAL ISSUES
(2024)
Article
Health Care Sciences & Services
Maria Bucek Psenkova, Lucia Hlavinkova, Martin Visnansky, Dominik Grega, Martina Ondrusova
Summary: This study developed a scientifically grounded checklist for economic evaluation (EE) of medicines in the Slovak health technology assessment process. The checklist was validated through an online survey and consists of 55 recommendations. Implementation of the checklist can help improve the appropriateness and standardization of EE in Slovakia.
VALUE IN HEALTH REGIONAL ISSUES
(2024)
Article
Health Care Sciences & Services
Sumit Mazumdar, Rana Hajjeh, Rick Brennan, Awad Mataria
Summary: This article discusses the important policy questions regarding health system financing in humanitarian settings, focusing on the Eastern Mediterranean region. The article explores the key financing functions in different challenges and suggests potential policy options. It also emphasizes the importance of collaborative research to inform policy choices aligned with universal health coverage in challenging contexts.
VALUE IN HEALTH REGIONAL ISSUES
(2024)
Article
Health Care Sciences & Services
Juliet Nabyonga-Orem, Edward Kataika, Alexandra Rollinger, Helen Weatherly
Summary: The Thanzi Programme is a research-and-policy partnership framework that supports evidence-informed health resource allocation decisions in Africa. It achieves this through providing health economics training, strengthening partnerships between in-country and international researchers, and institutionalizing platforms at national and regional levels. It also enhances the contribution of health economics evidence in policy processes through the establishment of Health Economics and Policy Units and the Health Economics Community of Practice.
VALUE IN HEALTH REGIONAL ISSUES
(2024)
Article
Health Care Sciences & Services
Majid Alsaha Fi, Mahmoud Mosli, Saad Alkhowaiter, Fergal Donnellan
Summary: This study compares the utility and ulcer recurrence rate of empiric treatment strategy and test and treat strategy in patients with uncomplicated duodenal ulcer. The results show that the empiric treatment strategy, within a specific range of test sensitivity, can lower the recurrence rate and result in higher quality-adjusted life-year (QALY) compared to the test and treat strategy.
VALUE IN HEALTH REGIONAL ISSUES
(2024)
Article
Health Care Sciences & Services
Dominik Grega, Jozef Kolar
Summary: This study aimed to compare the direct (biological drugs only) and indirect (productivity loss) costs in patients with rheumatoid arthritis during the study period. The results showed that the indirect costs were 2.5 to 3 times lower than the costs of biological and targeted treatment.
VALUE IN HEALTH REGIONAL ISSUES
(2024)
