Dystrophic cardiomyopathy: role of TRPV2 channels in stretch-induced cell damage

TRPV2 is critical for the maintenance of cardiac structure and function in mice

(2014) Yuki Katanosaka et al.   Nature Communications

Involvement of TRPV2 and SOCE in calcium influx disorder in DMD primary human myotubes with a specific contribution of α1-syntrophin and PLC/PKC in SOCE regulation

(2013) Rania Harisseh et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Novel role of transient receptor potential vanilloid 2 in the regulation of cardiac performance

(2013) Jack Rubinstein et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Blockade of sarcolemmal TRPV2 accumulation inhibits progression of dilated cardiomyopathy

(2013) Yuko Iwata et al.   CARDIOVASCULAR RESEARCH

Ultrastructural and Functional Alterations of EC Coupling Elements in mdx Cardiomyocytes: An Analysis from Membrane Surface to Depth

(2013) Charlotte Lorin et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

What do we know about the transient receptor potential vanilloid 2 (TRPV2) ion channel?

(2013) Alex Perálvarez-Marín et al.   FEBS Journal

Hierarchical accumulation of RyR post-translational modifications drives disease progression in dystrophic cardiomyopathy

(2012) Sergii Kyrychenko et al.   CARDIOVASCULAR RESEARCH

Oxidative and nitrosative stress in the maintenance of myocardial function

(2012) Yixuan Zhang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Probenecid: Novel use as a non-injurious positive inotrope acting via cardiac TRPV2 stimulation

(2012) Sheryl E. Koch et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Stretch-activated calcium channel protein TRPC1 is correlated with the different degrees of the dystrophic phenotype in mdx mice

(2011) Cíntia Yuri Matsumura et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Functional and morphological preservation of adult ventricular myocytes in culture by sub-micromolar cytochalasin D supplement

(2011) Qinghai Tian et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

X-ROS Signaling: Rapid Mechano-Chemo Transduction in Heart

(2011) B. L. Prosser et al.   SCIENCE

Insulin/phosphoinositide 3-kinase pathway accelerates the glucose-induced first-phase insulin secretion through TrpV2 recruitment in pancreatic β-cells

(2010) Kyota Aoyagi et al.   BIOCHEMICAL JOURNAL

Calcium and the damage pathways in muscular dystrophyThis article is one of a selection of papers published in this special issue on Calcium Signaling.

(2010) David G. Allen et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Duchenne muscular dystrophy – What causes the increased membrane permeability in skeletal muscle?

(2010) David G. Allen et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

International Union of Basic and Clinical Pharmacology. LXXVI. Current Progress in the Mammalian TRP Ion Channel Family

(2010) L.-J. Wu et al.   PHARMACOLOGICAL REVIEWS

Stretch-Activated Ion Channels: What Are They?

(2010) Frederick Sachs   PHYSIOLOGY

Leaky RyR2 trigger ventricular arrhythmias in Duchenne muscular dystrophy

(2010) J. Fauconnier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic inhibition of PKA phosphorylation of RyR2 prevents dystrophic cardiomyopathy

(2010) S. Sarma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hypersensitivity of excitation-contraction coupling in dystrophic cardiomyocytes

(2009) Nina D. Ullrich et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Pathways of abnormal stress-induced Ca2+ influx into dystrophic mdx cardiomyocytes

(2009) M. Fanchaouy et al.   CELL CALCIUM

Essential role of TRPV2 ion channel in the sensitivity of dystrophic muscle to eccentric contractions

(2009) Nadège Zanou et al.   FEBS LETTERS

Pharmacology of Vanilloid Transient Receptor Potential Cation Channels

(2009) J. Vriens et al.   MOLECULAR PHARMACOLOGY

Hypernitrosylated ryanodine receptor calcium release channels are leaky in dystrophic muscle

(2009) Andrew M Bellinger et al.   NATURE MEDICINE

Calcium influx is sufficient to induce muscular dystrophy through a TRPC-dependent mechanism

(2009) Douglas P. Millay et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanical deformation of ventricular myocytes modulates both TRPC6 and Kir2.3 channels

(2008) V. Dyachenko et al.   CELL CALCIUM

Dominant-negative inhibition of Ca2+ influx via TRPV2 ameliorates muscular dystrophy in animal models

(2008) Yuko Iwata et al.   HUMAN MOLECULAR GENETICS

Stretch-activated channels in the heart: Contributions to length-dependence and to cardiomyopathy

(2008) Marie-Louise Ward et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY