Succinate dehydrogenase inhibition with malonate during reperfusion reduces infarct size by preventing mitochondrial permeability transition

Myocardial Reperfusion Injury: Reactive Oxygen Species vs. NHE-1 Reactivation

(2017) Carolina D. Garciarena et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Combination therapy with remote ischaemic conditioning and insulin or exenatide enhances infarct size limitation in pigs

(2015) Juan José Alburquerque-Béjar et al.   CARDIOVASCULAR RESEARCH

The mitochondrial permeability transition: A current perspective on its identity and role in ischaemia/reperfusion injury

(2015) Andrew P. Halestrap et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Molecular identity of the mitochondrial permeability transition pore and its role in ischemia-reperfusion injury

(2015) Giampaolo Morciano et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The mitochondrial permeability transition pore: Molecular nature and role as a target in cardioprotection

(2015) Paolo Bernardi et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Remote Ischemic Conditioning

(2015) Gerd Heusch et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Transient complex I inhibition at the onset of reperfusion by extracellular acidification decreases cardiac injury

(2014) Aijun Xu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Cardiac Mitochondria and Reactive Oxygen Species Generation

(2014) Yeong-Renn Chen et al.   CIRCULATION RESEARCH

Microtubule stabilization with paclitaxel does not protect against infarction in isolated rat hearts

(2014) Antonio Rodríguez-Sinovas et al.   EXPERIMENTAL PHYSIOLOGY

Ischemic preconditioning protects cardiomyocyte mitochondria through mechanisms independent of cytosol

(2014) Marisol Ruiz-Meana et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS

(2014) Edward T. Chouchani et al.   NATURE

Activation of RISK and SAFE pathways is not involved in the effects of Cx43 deficiency on tolerance to ischemia–reperfusion injury and preconditioning protection

(2013) Jose A. Sánchez et al.   BASIC RESEARCH IN CARDIOLOGY

Q-site inhibitor induced ROS production of mitochondrial complex II is attenuated by TCA cycle dicarboxylates

(2013) Ilka Siebels et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Eplerenone attenuated cardiac steatosis, apoptosis and diastolic dysfunction in experimental type-II diabetes

(2013) Elisa Ramírez et al.   Cardiovascular Diabetology

Myocardial ischemia-reperfusion injury: a neglected therapeutic target

(2013) Derek J. Hausenloy et al.   JOURNAL OF CLINICAL INVESTIGATION

Activation of cGMP/Protein Kinase G Pathway in Postconditioned Myocardium Depends on Reduced Oxidative Stress and Preserved Endothelial Nitric Oxide Synthase Coupling

(2013) Javier Inserte et al.   Journal of the American Heart Association

Inhibition of complex I regulates the mitochondrial permeability transition through a phosphate-sensitive inhibitory site masked by cyclophilin D

(2012) Bo Li et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Calcium-mediated cell death during myocardial reperfusion

(2012) D. Garcia-Dorado et al.   CARDIOVASCULAR RESEARCH

Mitochondrial Complex II Can Generate Reactive Oxygen Species at High Rates in Both the Forward and Reverse Reactions

(2012) Casey L. Quinlan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The role of mitochondrial permeability transition in reperfusion-induced cardiomyocyte death depends on the duration of ischemia

(2011) Marisol Ruiz-Meana et al.   BASIC RESEARCH IN CARDIOLOGY

Investigating the Signal Transduction Pathways Underlying Remote Ischemic Conditioning in the Porcine Heart

(2011) D. J. Hausenloy et al.   CARDIOVASCULAR DRUGS AND THERAPY

Mitochondrial STAT3 Activation and Cardioprotection by Ischemic Postconditioning in Pigs With Regional Myocardial Ischemia/Reperfusion

(2011) Gerd Heusch et al.   CIRCULATION RESEARCH

A Common Mechanism Links Differently Acting Complex II Inhibitors to Cardioprotection: Modulation of Mitochondrial Reactive Oxygen Species Production

(2011) S. Drose et al.   MOLECULAR PHARMACOLOGY

Mitochondrial Injury and Protection in Ischemic Pre- and Postconditioning

(2010) Fabio Di Lisa et al.   ANTIOXIDANTS & REDOX SIGNALING

Inhibition of mitochondrial permeability transition pore opening: the holy grail of cardioprotection

(2010) Gerd Heusch et al.   BASIC RESEARCH IN CARDIOLOGY

Inhibition of permeability transition pore opening by mitochondrial STAT3 and its role in myocardial ischemia/reperfusion

(2010) Kerstin Boengler et al.   BASIC RESEARCH IN CARDIOLOGY

Kinases and phosphatases in ischaemic preconditioning: a re-evaluation

(2010) W. J. Fan et al.   BASIC RESEARCH IN CARDIOLOGY

Role of sarcoplasmic reticulum in mitochondrial permeability transition and cardiomyocyte death during reperfusion

(2009) Marisol Ruiz-Meana et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

The complex II inhibitor atpenin A5 protects against cardiac ischemia-reperfusion injury via activation of mitochondrial KATP channels

(2009) Andrew P. Wojtovich et al.   BASIC RESEARCH IN CARDIOLOGY

Cardioprotection: A radical view

(2009) Claudia Penna et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Reversible blockade of electron transport with amobarbital at the onset of reperfusion attenuates cardiac injury

(2009) Sarah Stewart et al.   Translational Research

Heart rate in the pathophysiology of coronary blood flow and myocardial ischaemia: benefit from selective bradycardic agents

(2008) G Heusch   BRITISH JOURNAL OF PHARMACOLOGY

Mechanisms Underlying Acute Protection From Cardiac Ischemia-Reperfusion Injury

(2008) Elizabeth Murphy et al.   PHYSIOLOGICAL REVIEWS