Insulin treatment increases myocardial ceramide accumulation and disrupts cardiometabolic function
出版年份 2015 全文链接
标题
Insulin treatment increases myocardial ceramide accumulation and disrupts cardiometabolic function
作者
关键词
Insulin, Hyperinsulinemia, Mitochondria, Ceramide
出版物
Cardiovascular Diabetology
Volume 14, Issue 1, Pages -
出版商
Springer Nature
发表日期
2015-12-18
DOI
10.1186/s12933-015-0316-y
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Cardiomyocyte mitochondrial respiration is reduced by receptor for advanced glycation end-product signaling in a ceramide-dependent manner
- (2015) Michael B. Nelson et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- High daily insulin exposure in patients with type 2 diabetes is associated with increased risk of cardiovascular events
- (2015) R.M. Stoekenbroek et al. ATHEROSCLEROSIS
- Targeting metabolic disturbance in the diabetic heart
- (2015) Jesús Fuentes-Antrás et al. Cardiovascular Diabetology
- Cigarette smoke increases cardiomyocyte ceramide accumulation and inhibits mitochondrial respiration
- (2014) Trevor S Tippetts et al. BMC Cardiovascular Disorders
- Cardiac contractile function and mitochondrial respiration in diabetes-related mouse models
- (2014) Camille Marciniak et al. Cardiovascular Diabetology
- Insulin Increases Ceramide Synthesis in Skeletal Muscle
- (2014) M. E. Hansen et al. Journal of Diabetes Research
- Mitochondrial fission mediates ceramide-induced metabolic disruption in skeletal muscle
- (2013) Melissa E. Smith et al. BIOCHEMICAL JOURNAL
- Insulin Stimulates Mitochondrial Fusion and Function in Cardiomyocytes via the Akt-mTOR-NF B-Opa-1 Signaling Pathway
- (2013) V. Parra et al. DIABETES
- Impact of Diabetes on Cardiovascular Disease: An Update
- (2013) Alessandra Saldanha de Mattos Matheus et al. International Journal of Hypertension
- Ceramide Mediates Vascular Dysfunction in Diet-Induced Obesity by PP2A-Mediated Dephosphorylation of the eNOS-Akt Complex
- (2012) Q.-J. Zhang et al. DIABETES
- Diabetes: Have We Got It All Wrong?: Hyperinsulinism as the culprit: surgery provides the evidence
- (2012) W. J. Pories et al. DIABETES CARE
- Ablation of Dihydroceramide Desaturase Confers Resistance to Etoposide-Induced Apoptosis In Vitro
- (2012) Monowarul M. Siddique et al. PLoS One
- AICAR inhibits ceramide biosynthesis in skeletal muscle
- (2012) Katherine A Erickson et al. Diabetology & Metabolic Syndrome
- Assessing mitochondrial dysfunction in cells
- (2011) Martin D. Brand et al. BIOCHEMICAL JOURNAL
- The worldwide epidemiology of type 2 diabetes mellitus—present and future perspectives
- (2011) Lei Chen et al. Nature Reviews Endocrinology
- Prevalence and Determinant Factors of Sarcopenia in Patients With Type 2 Diabetes: The Korean Sarcopenic Obesity Study (KSOS)
- (2010) T. N. Kim et al. DIABETES CARE
- Excessive cardiac insulin signaling exacerbates systolic dysfunction induced by pressure overload in rodents
- (2010) Ippei Shimizu et al. JOURNAL OF CLINICAL INVESTIGATION
- Receptor-mediated activation of ceramidase activity initiates the pleiotropic actions of adiponectin
- (2010) William L Holland et al. NATURE MEDICINE
- The importance of titrating starting insulin regimens in patients with type 2 diabetes
- (2009) A. J. Garber DIABETES OBESITY & METABOLISM
- The Pathologic Continuum of Diabetic Vascular Disease
- (2009) Gabriela Orasanu et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Ceramide is a cardiotoxin in lipotoxic cardiomyopathy
- (2008) Tae-Sik Park et al. JOURNAL OF LIPID RESEARCH
- Intensive Blood Glucose Control and Vascular Outcomes in Patients with Type 2 Diabetes
- (2008) NEW ENGLAND JOURNAL OF MEDICINE
- Effects of Intensive Glucose Lowering in Type 2 Diabetes
- (2008) NEW ENGLAND JOURNAL OF MEDICINE
- 10-Year Follow-up of Intensive Glucose Control in Type 2 Diabetes
- (2008) Rury R. Holman et al. NEW ENGLAND JOURNAL OF MEDICINE
- Glucose Control and Vascular Complications in Veterans with Type 2 Diabetes
- (2008) William Duckworth et al. NEW ENGLAND JOURNAL OF MEDICINE
- Serine palmitoyltransferase inhibitor myriocin induces the regression of atherosclerotic plaques in hyperlipidemic ApoE-deficient mice
- (2008) T PARK et al. PHARMACOLOGICAL RESEARCH
- Mechanisms of Disease: advanced glycation end-products and their receptor in inflammation and diabetes complications
- (2008) Shi Fang Yan et al. Nature clinical practice. Endocrinology & metabolism
- Adiponectin, Cardiovascular Function, and Hypertension
- (2007) Zhao V. Wang et al. HYPERTENSION
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