Whole genome-wide analysis of DEP family members in sheep (Ovis aries) reveals their potential roles in regulating lactation

Genomic studies of milk-related traits in water buffalo (Bubalus bubalis) based on single-step genomic best linear unbiased prediction and random regression models

(2021) Sirlene F. Lázaro et al.   JOURNAL OF DAIRY SCIENCE

Regulation of Dishevelled DEP domain swapping by conserved phosphorylation sites

(2021) Gonzalo J. Beitia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Whole Genome Level Analysis of the Wnt and DIX Gene Families in Mice and Their Coordination Relationship in Regulating Cardiac Hypertrophy

(2021) Zhongchao Gai et al.   Frontiers in Genetics

Genome-wide association study with imputed whole-genome sequence variants including large deletions for female fertility in 3 Nordic dairy cattle breeds

(2021) Md Mesbah-Uddin et al.   JOURNAL OF DAIRY SCIENCE

Effects of progesterone concentrations and follicular wave during growth of the ovulatory follicle on conceptus and endometrial transcriptome in dairy cows

(2021) R.S. Bisinotto et al.   JOURNAL OF DAIRY SCIENCE

Gene family expansion of pinewood nematode to detoxify its host defence chemicals

(2020) Wei Zhang et al.   MOLECULAR ECOLOGY

Genome-wide identification and characterization of Toll-like receptors (TLRs) in housefly (Musca domestica) and their roles in the insecticide resistance

(2020) Jieqiong Zhao et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Thyroid hormone profiles and TSH evaluation during early pregnancy and the transition period in dairy cows

(2019) L. Steinhoff et al.   THERIOGENOLOGY

Underlying mechanisms of recombinant adeno-associated virus-mediated bicaudal C homolog 1 overexpression in the medial prefrontal cortex of mice with induced depressive-like behaviors

(2019) Zhengchun Wang et al.   BRAIN RESEARCH BULLETIN

PIKfyve Deficiency in Myeloid Cells Impairs Lysosomal Homeostasis in Macrophages and Promotes Systemic Inflammation in Mice

(2019) Sang Hee Min et al.   MOLECULAR AND CELLULAR BIOLOGY

Phosphorylation of DEPDC5, a component of the GATOR1 complex, releases inhibition of mTORC1 and promotes tumor growth

(2019) Sathish K. R. Padi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-wide analysis reveals the functional and expressional correlation between RhoGAP and RhoGEF in mouse

(2019) Zhongchao Gai et al.   GENOMICS

DEPTOR is an in vivo tumor suppressor that inhibits prostate tumorigenesis via the inactivation of mTORC1/2 signals

(2019) Xiaoyu Chen et al.   ONCOGENE

Prolactin signaling drives tumorigenesis in human high grade serous ovarian cancer cells and in a spontaneous fallopian tube derived model

(2018) Subbulakshmi Karthikeyan et al.   CANCER LETTERS

MicroRNA-221 may be involved in lipid metabolism in mammary epithelial cells

(2018) Meiqiang Chu et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Akt Serine/Threonine Kinase 1 Regulates de Novo Fatty Acid Synthesis through the Mammalian Target of Rapamycin/Sterol Regulatory Element Binding Protein 1 Axis in Dairy Goat Mammary Epithelial Cells

(2018) Tianying Zhang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

GATOR1-dependent recruitment of FLCN–FNIP to lysosomes coordinates Rag GTPase heterodimer nucleotide status in response to amino acids

(2018) Jin Meng et al.   JOURNAL OF CELL BIOLOGY

RagD regulates amino acid mediated-casein synthesis and cell proliferation via mTOR signalling in cow mammary epithelial cells

(2018) Ying Mu et al.   JOURNAL OF DAIRY RESEARCH

Overview of Nutrients in Human Milk

(2018) Daphna K Dror et al.   Advances in Nutrition

Th-POK regulates mammary gland lactation through mTOR-SREBP pathway

(2018) Rui Zhang et al.   PLoS Genetics

Suppression of insulin feedback enhances the efficacy of PI3K inhibitors

(2018) Benjamin D. Hopkins et al.   NATURE

The Role of Placental Hormones in Mediating Maternal Adaptations to Support Pregnancy and Lactation

(2018) Tina Napso et al.   Frontiers in Physiology

DEPDC1, negatively regulated by miR-26b, facilitates cell proliferation via the up-regulation of FOXM1 expression in TNBC

(2018) Lei Zhang et al.   CANCER LETTERS

A 100-Year Review: Mammary development and lactation

(2017) R. Michael Akers   JOURNAL OF DAIRY SCIENCE

Association of single nucleotide polymorphisms in candidate genes previously related to genetic variation in fertility with phenotypic measurements of reproductive function in Holstein cows

(2017) M. Sofia Ortega et al.   JOURNAL OF DAIRY SCIENCE

Prolactin regulation of oxytocin neurone activity in pregnancy and lactation

(2017) Rachael A. Augustine et al.   JOURNAL OF PHYSIOLOGY-LONDON

Hypothyroidism decreases JAK/STAT signaling pathway in lactating rat mammary gland

(2017) Fiorella Campo Verde Arboccó et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Biological underpinnings of breastfeeding challenges: the role of genetics, diet, and environment on lactation physiology

(2016) Sooyeon Lee et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

PIKfyve Regulates Vacuole Maturation and Nutrient Recovery following Engulfment

(2016) Shefali Krishna et al.   DEVELOPMENTAL CELL

Appetite-regulating hormones in early life and relationships with type of feeding and body composition in healthy term infants

(2016) Laura M. Breij et al.   EUROPEAN JOURNAL OF NUTRITION

Cell survival signaling in the bovine mammary gland during the transition from lactation to involution

(2016) K. Singh et al.   JOURNAL OF DAIRY SCIENCE

Evolview v2: an online visualization and management tool for customized and annotated phylogenetic trees

(2016) Zilong He et al.   NUCLEIC ACIDS RESEARCH

Effect of hyperprolactinemia on PRL-receptor expression and activation of Stat and Mapk cell signaling in the prostate of long-term sexually-active rats

(2016) Luz I. Pascual-Mathey et al.   PHYSIOLOGY & BEHAVIOR

Structure of the TBC1D7–TSC1 complex reveals that TBC1D7 stabilizes dimerization of the TSC1 C-terminal coiled coil region

(2016) Zhongchao Gai et al.   Journal of Molecular Cell Biology

Structural mechanism for the arginine sensing and regulation of CASTOR1 in the mTORC1 signaling pathway

(2016) Zhongchao Gai et al.   Cell Discovery

Functional development of the adult ovine mammary gland—insights from gene expression profiling

(2015) Amy M Paten et al.   BMC GENOMICS

Exchange protein directly activated by cAMP encoded by the mammalian rapgef3 gene: Structure, function and therapeutics

(2015) Upasana Banerjee et al.   GENE

EGF-mediated induction of Mcl-1 at the switch to lactation is essential for alveolar cell survival

(2015) Nai Yang Fu et al.   NATURE CELL BIOLOGY

Structures of the APC–ARM domain in complexes with discrete Amer1/WTX fragments reveal that it uses a consensus mode to recognize its binding partners

(2015) Zhenyi Zhang et al.   Cell Discovery

Suckling and Salsolinol Attenuate Responsiveness of the Hypothalamic-Pituitary-Adrenal Axis to Stress: Focus on Catecholamines, Corticotrophin-Releasing Hormone, Adrenocorticotrophic Hormone, Cortisol and Prolactin Secretion in Lactating Sheep

(2014) M. Hasiec et al.   JOURNAL OF NEUROENDOCRINOLOGY

DEP domains: structurally similar but functionally different

(2014) Sarah V. Consonni et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

MCScanX: a toolkit for detection and evolutionary analysis of gene synteny and collinearity

(2012) Y. Wang et al.   NUCLEIC ACIDS RESEARCH

mTORC1- and mTORC2-interacting proteins keep their multifunctional partners focused

(2011) Ismael Bracho-Valdés et al.   IUBMB LIFE

Studying the co-evolution of protein families with the Mirrortree web server

(2010) David Ochoa et al.   BIOINFORMATICS

KaKs_Calculator 2.0: A Toolkit Incorporating Gamma-Series Methods and Sliding Window Strategies

(2010) Dapeng Wang et al.   GENOMICS PROTEOMICS & BIOINFORMATICS

DEPTOR Is an mTOR Inhibitor Frequently Overexpressed in Multiple Myeloma Cells and Required for Their Survival

(2009) Timothy R. Peterson et al.   CELL

Correlation Between Ka/Ks and Ks is Related to Substitution Model and Evolutionary Lineage

(2009) Jun Li et al.   JOURNAL OF MOLECULAR EVOLUTION

Activation of the PI3K Pathway in Cancer Through Inhibition of PTEN by Exchange Factor P-REX2a

(2009) B. Fine et al.   SCIENCE