The contribution of Aspergillus fumigatus stress responses to virulence and antifungal resistance

The Aspergillus fumigatus sitA Phosphatase Homologue Is Important for Adhesion, Cell Wall Integrity, Biofilm Formation, and Virulence

(2015) Vinícius Leite Pedro Bom et al.   EUKARYOTIC CELL

High osmolarity glycerol response PtcB phosphatase is important forAspergillus fumigatusvirulence

(2015) Lizziane K. Winkelströter et al.   MOLECULAR MICROBIOLOGY

The Aspergillus fumigatus pkcAG579R Mutant Is Defective in the Activation of the Cell Wall Integrity Pathway but Is Dispensable for Virulence in a Neutropenic Mouse Infection Model

(2015) Marina Campos Rocha et al.   PLoS One

Systematic Global Analysis of Genes Encoding Protein Phosphatases in Aspergillus fumigatus

(2015) Lizziane K. Winkelströter et al.   G3-Genes Genomes Genetics

The Aspergillus fumigatus cell wall integrity signaling pathway: drug target, compensatory pathways, and virulence

(2015) Vito Valiante et al.   Frontiers in Microbiology

The importance of connections between the cell wall integrity pathway and the unfolded protein response in filamentous fungi

(2014) I. Malavazi et al.   Briefings in Functional Genomics

ChIP-seq reveals a role for CrzA in theAspergillus fumigatushigh-osmolarity glycerol response (HOG) signalling pathway

(2014) Patrícia A. de Castro et al.   MOLECULAR MICROBIOLOGY

Calcineurin-Mediated Regulation of Hyphal Growth, Septation, and Virulence in Aspergillus fumigatus

(2014) Praveen R. Juvvadi et al.   MYCOPATHOLOGIA

Aspergillus Cell Wall and Biofilm

(2014) Anne Beauvais et al.   MYCOPATHOLOGIA

The Involvement of the Mid1/Cch1/Yvc1 Calcium Channels in Aspergillus fumigatus Virulence

(2014) Patrícia Alves de Castro et al.   PLoS One

The pH-Responsive PacC Transcription Factor of Aspergillus fumigatus Governs Epithelial Entry and Tissue Invasion during Pulmonary Aspergillosis

(2014) Margherita Bertuzzi et al.   PLoS Pathogens

ChIP-seq and In Vivo Transcriptome Analyses of the Aspergillus fumigatus SREBP SrbA Reveals a New Regulator of the Fungal Hypoxia Response and Virulence

(2014) Dawoon Chung et al.   PLoS Pathogens

Transcriptomic Insights into the Oxidative Response of Stress-Exposed Aspergillus fumigatus

(2013) Emilie Frealle et al.   CURRENT PHARMACEUTICAL DESIGN

Azole resistant Aspergillus fumigatus: An emerging problem

(2013) L. Lelièvre et al.   MEDECINE ET MALADIES INFECTIEUSES

NikA/TcsC Histidine Kinase Is Involved in Conidiation, Hyphal Morphology, and Responses to Osmotic Stress and Antifungal Chemicals in Aspergillus fumigatus

(2013) Daisuke Hagiwara et al.   PLoS One

The fungal UPR

(2013) Karthik Krishnan et al.   Virulence

Aspergillus fumigatus melanins: interference with the host endocytosis pathway and impact on virulence

(2013) Thorsten Heinekamp et al.   Frontiers in Microbiology

Comparison of transcriptome technologies in the pathogenic fungus Aspergillus fumigatus reveals novel insights into the genome and MpkA dependent gene expression

(2012) Sebastian Müller et al.   BMC GENOMICS

Heat Shock Protein 90 Is Required for Conidiation and Cell Wall Integrity in Aspergillus fumigatus

(2012) Frédéric Lamoth et al.   EUKARYOTIC CELL

Molecular Characterization of the Putative Transcription Factor SebA Involved in Virulence in Aspergillus fumigatus

(2012) Taísa Magnani Dinamarco et al.   EUKARYOTIC CELL

Fungal antioxidant pathways promote survival against neutrophils during infection

(2012) Sixto M. Leal et al.   JOURNAL OF CLINICAL INVESTIGATION

Functional Characterization of an Aspergillus fumigatus Calcium Transporter (PmcA) that Is Essential for Fungal Infection

(2012) Taísa Magnani Dinamarco et al.   PLoS One

The Two-Component Sensor Kinase TcsC and Its Role in Stress Resistance of the Human-Pathogenic Mold Aspergillus fumigatus

(2012) Allison McCormick et al.   PLoS One

Hidden Killers: Human Fungal Infections

(2012) G. D. Brown et al.   Science Translational Medicine

Iron homeostasis—Achilles’ heel of Aspergillus fumigatus?

(2011) Markus Schrettl et al.   CURRENT OPINION IN MICROBIOLOGY

The metalloreductase FreB is involved in adaptation of Aspergillus fumigatus to iron starvation

(2011) Michael Blatzer et al.   FUNGAL GENETICS AND BIOLOGY

The MAP kinase MpkA controls cell wall integrity, oxidative stress response, gliotoxin production and iron adaptation in Aspergillus fumigatus

(2011) Radhika Jain et al.   MOLECULAR MICROBIOLOGY

SREBP Coordinates Iron and Ergosterol Homeostasis to Mediate Triazole Drug and Hypoxia Responses in the Human Fungal Pathogen Aspergillus fumigatus

(2011) Michael Blatzer et al.   PLoS Genetics

HacA-Independent Functions of the ER Stress Sensor IreA Synergize with the Canonical UPR to Influence Virulence Traits in Aspergillus fumigatus

(2011) Xizhi Feng et al.   PLoS Pathogens

In vivo Hypoxia and a Fungal Alcohol Dehydrogenase Influence the Pathogenesis of Invasive Pulmonary Aspergillosis

(2011) Nora Grahl et al.   PLoS Pathogens

Transcriptional Regulation of Chitin Synthases by Calcineurin Controls Paradoxical Growth of Aspergillus fumigatus in Response to Caspofungin

(2010) J. R. Fortwendel et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Augmenting the activity of antifungal agents against aspergilli using structural analogues of benzoic acid as chemosensitizing agents

(2010) Jong H. Kim et al.   Fungal Biology

AfMkk2 is required for cell wall integrity signaling, adhesion, and full virulence of the human pathogen Aspergillus fumigatus

(2010) Franziska Dirr et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Implications of hypoxic microenvironments during invasive aspergillosis

(2010) Sara J. Wezensky et al.   MEDICAL MYCOLOGY

Functional analysis of the superoxide dismutase family inAspergillus fumigatus

(2010) Karine Lambou et al.   MOLECULAR MICROBIOLOGY

Aspergillus fumigatus AcuM regulates both iron acquisition and gluconeogenesis

(2010) Hong Liu et al.   MOLECULAR MICROBIOLOGY

HapX-Mediated Adaption to Iron Starvation Is Crucial for Virulence of Aspergillus fumigatus

(2010) Markus Schrettl et al.   PLoS Pathogens

Pathogenesis of Aspergillus fumigatus in Invasive Aspergillosis

(2009) T. R. T. Dagenais et al.   CLINICAL MICROBIOLOGY REVIEWS

Nitrosative and oxidative stress responses in fungal pathogenicity

(2009) Alistair JP Brown et al.   CURRENT OPINION IN MICROBIOLOGY

The MpkA MAP kinase module regulates cell wall integrity signaling and pyomelanin formation in Aspergillus fumigatus

(2009) Vito Valiante et al.   FUNGAL GENETICS AND BIOLOGY

Vertebrate Endothermy Restricts Most Fungi as Potential Pathogens

(2009) Vincent A. Robert et al.   JOURNAL OF INFECTIOUS DISEASES

Harnessing Hsp90 function as a powerful, broadly effective therapeutic strategy for fungal infectious disease

(2009) Leah E. Cowen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Role for the Unfolded Protein Response (UPR) in Virulence and Antifungal Susceptibility in Aspergillus fumigatus

(2009) Daryl L. Richie et al.   PLoS Pathogens

Breakthrough Aspergillus fumigatus and Candida albicans Double Infection during Caspofungin Treatment: Laboratory Characteristics and Implication for Susceptibility Testing

(2008) M. C. Arendrup et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Calcineurin Target CrzA Regulates Conidial Germination, Hyphal Growth, and Pathogenesis ofAspergillus fumigatus

(2008) Robert A. Cramer et al.   EUKARYOTIC CELL

Basal expression of the Aspergillus fumigatus transcriptional activator CpcA is sufficient to support pulmonary aspergillosis

(2008) Christoph Sasse et al.   FUNGAL GENETICS AND BIOLOGY

The Sho1 Sensor Regulates Growth, Morphology, and Oxidant Adaptation in Aspergillus fumigatus but Is Not Essential for Development of Invasive Pulmonary Aspergillosis

(2008) Y. Ma et al.   INFECTION AND IMMUNITY

SreA-mediated iron regulation in Aspergillus fumigatus

(2008) Markus Schrettl et al.   MOLECULAR MICROBIOLOGY

Functional characterization of the Aspergillus fumigatus CRZ1 homologue, CrzA

(2008) Frederico Marianetti Soriani et al.   MOLECULAR MICROBIOLOGY

The evolution of fungal drug resistance: modulating the trajectory from genotype to phenotype

(2008) Leah E. Cowen   NATURE REVIEWS MICROBIOLOGY

Ambient pH gene regulation in fungi: making connections

(2008) Miguel A. Peñalva et al.   TRENDS IN MICROBIOLOGY

Sub-Telomere Directed Gene Expression during Initiation of Invasive Aspergillosis

(2008) Andrew McDonagh et al.   PLoS Pathogens

A Sterol-Regulatory Element Binding Protein Is Required for Cell Polarity, Hypoxia Adaptation, Azole Drug Resistance, and Virulence in Aspergillus fumigatus

(2008) Sven D. Willger et al.   PLoS Pathogens

The mitogen-activated protein kinase MpkA of Aspergillus fumigatus regulates cell wall signaling and oxidative stress response

(2007) Vito Valiante et al.   FUNGAL GENETICS AND BIOLOGY