A Review on Therapeutic Potential of Natural Phytocompounds for Stroke

Stroke is a serious condition that results from an occlusion of blood vessels that leads to brain damage. Globally, it is the second highest cause of death, and deaths from strokes are higher in older people than in the young. There is a higher rate of cases in urban areas compared to rural due to lifestyle, food, and pollution. There is no effective single medicine for the treatment of stroke due to the multiple causes of strokes. Thrombolytic agents, such as alteplase, are the main treatment for thrombolysis, while multiple types of surgeries, such ascraniotomy, thrombectomy, carotid endarterectomy, and hydrocephalus, can be performed for various forms of stroke. In this review, we discuss some promising phytocompounds, such as flavone C-glycoside (apigenin-8-C-beta-D-glucopyranoside), eriodictyol, rosamirinic acid, 6 ''-O-succinylapigenin, and allicin, that show effectiveness against stroke. Future study paths are given, as well as suggestions for expanding the use of medicinal plants and their formulations for stroke prevention.

Automated summary

Stroke is a serious condition caused by occlusion of blood vessels leading to brain damage, with older people and urban areas having higher rates of occurrence. Currently, there is no single effective medicine for stroke treatment, with options including thrombolytic agents and various surgical procedures. Promising natural compounds have shown effectiveness against stroke, providing potential for future research and development.