Therapeutic Effects of Silibinin Against Polycystic Ovary Syndrome Induced by Letrozole in Rats via Its Potential Anti-Inflammatory and Anti-Oxidant Activities

Naringenin and morin reduces insulin resistance and endometrial hyperplasia in the rat model of polycystic ovarian syndrome through enhancement of inflammation and autophagic apoptosis

(2022) Yi Yang et al.   ACTA BIOCHIMICA POLONICA

Role of inflammatory markers in polycystic ovaries syndrome: In relation to insulin resistance

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Chronic Low Grade Inflammation in Pathogenesis of PCOS

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Quercetin and polycystic ovary syndrome, current evidence and future directions: a systematic review

(2020) Fatemeh Pourteymour Fard Tabrizi et al.   Journal of Ovarian Research

Beneficial phytoestrogenic effects of resveratrol on polycystic ovary syndromein rat model

(2020) Ning Zhang et al.   GYNECOLOGICAL ENDOCRINOLOGY

Phyllanthus muellerianus (Euphorbiaceae) Restores Ovarian Functions in Letrozole-Induced Polycystic Ovarian Syndrome in Rats

(2019) Eveline Christiane Ndeingang et al.   Evidence-based Complementary and Alternative Medicine

Treatment with metformin and sorafenib alleviates endometrial hyperplasia in polycystic ovary syndrome by promoting apoptosis via synergically regulating autophagy

(2019) Qian-qing Wang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Effect of resveratrol and metformin on ovarian reserve and ultrastructure in PCOS: an experimental study

(2018) Selenay Furat Rencber et al.   Journal of Ovarian Research

Silibinin alleviates inflammation and induces apoptosis in human rheumatoid arthritis fibroblast-like synoviocytes and has a therapeutic effect on arthritis in rats

(2018) W. W. Tong et al.   Scientific Reports

The Natural Agonist of Estrogen Receptor β Silibinin Plays an Immunosuppressive Role Representing a Potential Therapeutic Tool in Rheumatoid Arthritis

(2018) Maria Luisa Dupuis et al.   Frontiers in Immunology

Androgen Action in the Ovary

(2018) Stephen Franks et al.   Frontiers in Endocrinology

Silybin, a Major Bioactive Component of Milk Thistle (Silybum marianum L. Gaernt.)—Chemistry, Bioavailability, and Metabolism

(2017) Michal Bijak   MOLECULES

Silibinin treatment prevents endotoxin-induced uveitis in rats in vivo and in vitro

(2017) Ching-Long Chen et al.   PLoS One

The pathogenesis and treatment of polycystic ovary syndrome: What’s new?

(2017) Sylwia Bednarska et al.   Advances in Clinical and Experimental Medicine

New concepts for an old problem: the diagnosis of endometrial hyperplasia

(2016) Peter A. Sanderson et al.   HUMAN REPRODUCTION UPDATE

Roles of Oxidative Stress in Polycystic Ovary Syndrome and Cancers

(2016) Tao Zuo et al.   Oxidative Medicine and Cellular Longevity

Soy isoflavones exert beneficial effects on letrozole-induced rat polycystic ovary syndrome (PCOS) model through anti-androgenic mechanism

(2016) Ravi Kumar Rajan et al.   PHARMACEUTICAL BIOLOGY

Polycystic ovary syndrome

(2016) Ricardo Azziz et al.   Nature Reviews Disease Primers

Association between Polycystic Ovary Syndrome and Gut Microbiota

(2016) Yanjie Guo et al.   PLoS One

Blockade of lipid accumulation by silibinin in adipocytes and zebrafish

(2015) Hyung Joo Suh et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Silibinin Inhibits ICAM-1 Expression via Regulation of N-Linked and O-Linked Glycosylation in ARPE-19 Cells

(2014) Yi-Hao Chen et al.   Biomed Research International

A Possible New Mechanism in the Pathophysiology of Polycystic Ovary Syndrome (PCOS): The Discovery That Leukocyte Telomere Length Is Strongly Associated With PCOS

(2013) Qiaoli Li et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Epidemiology, diagnosis, and management of polycystic ovary syndrome

(2013) Susan Sirmans et al.   Clinical Epidemiology

Mediators of chronic inflammation in polycystic ovarian syndrome

(2012) E. Deligeoroglou et al.   GYNECOLOGICAL ENDOCRINOLOGY

Silibinin inhibits prostate cancer cells- and RANKL-induced osteoclastogenesis by targeting NFATc1, NF-κB, and AP-1 activation in RAW264.7 cells

(2012) Chandagirikoppal V. Kavitha et al.   MOLECULAR CARCINOGENESIS

Is PCOS an inflammatory process?

(2011) Antoni J. Duleba et al.   FERTILITY AND STERILITY

Neuroendocrine dysfunction in polycystic ovary syndrome

(2011) Christine M. Burt Solorzano et al.   STEROIDS

Free radical scavenging activity of silibinin in nitrite-induced hemoglobin oxidation and membrane fragility models

(2011) Bushra H. Marouf et al.   SAUDI PHARMACEUTICAL JOURNAL

Downregulation of nuclear factor-kappa B (NF-κB) pathway by silibinin in human monocytes challenged with Paracoccidioides brasiliensis

(2010) Camila Ferreira Bannwart et al.   LIFE SCIENCES

The role of low-grade inflammation in the polycystic ovary syndrome

(2010) Andrea Repaci et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Inhibitory effect of silibinin on tumour necrosis factor-alpha and hydrogen peroxide production by human monocytes

(2010) C.F. Bannwart et al.   NATURAL PRODUCT RESEARCH

Evidence of proatherogenic inflammation in polycystic ovary syndrome

(2009) Frank González et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Evidences for antiosteoporotic and selective estrogen receptor modulator activity of silymarin compared with ethinylestradiol in ovariectomized rats

(2009) Nagla A. El-Shitany et al.   PHYTOMEDICINE