4.6 Article

Plasma Metabolomics Reveals β-Glucan Improves Muscle Strength and Exercise Capacity in Athletes

期刊

METABOLITES
卷 12, 期 10, 页码 -

出版社

MDPI
DOI: 10.3390/metabo12100988

关键词

beta-glucan; exercise; muscle strength; muscle mass; VO2max

资金

  1. National Natural Science Foundation of China [31971097, 32271226]
  2. National Key R&D Program of China [2020YFA0803800, 2019YFF0301702]
  3. Shanghai Municipal Science and Technology Committee of Shanghai outstanding academic leaders plan [21XD1403200]
  4. Construction Project of High-Level Local Universities in Shanghai, China

向作者/读者索取更多资源

The present study aimed to assess the effects of beta-glucan supplementation on muscle strength and plasma metabolites in athletes. The results showed that beta-glucan supplementation can improve muscle strength, enhance aerobic endurance, and enhance immune function, possibly by affecting creatine-related pathways.
The present study aimed to assess the changes in muscle strength and plasma metabolites in athletes with beta-glucan supplementation. A total of 29 athletes who met the inclusion criteria were recruited for this study (ChiCTR2200058091) and were randomly divided into a placebo group (n = 14) and beta-glucan group (n = 15). During the trial, the experimental group received beta-glucan supplementation (2 g/d beta-glucan) for 4 weeks and the control group received an equal dose of placebo supplementation (0 g/d beta-glucan), with both groups maintaining their regular diet and exercise habits during the trial. The athletes' exercise performance, muscle strength, and plasma metabolome changes were analyzed after 4 weeks of beta-glucan supplementation. The results showed a significant increase in mean grip strength (kg), right hand grip strength (kg), left triceps strength (kg), and upper limb muscle mass (kg) in the experimental group after the 4-week intervention compared to the preintervention period (p < 0.05). A comparison of the difference between the two groups after the intervention showed that there were significant differences between the control group and the experimental group in mean grip strength (kg) and right-hand grip strength (kg) (p < 0.05). Athletes in the experimental group showed significant improvements in 1 min double rocking jump (pcs), VO2max (ml/kg-min) (p < 0.05). The beta-glucan intake increased the creatine-related pathway metabolites in plasma. Overall, these results suggest that 4 weeks of beta-glucan supplementation can improve muscle strength in athletes, with the potential to increase aerobic endurance and enhance immune function, possibly by affecting creatine-related pathways.

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