Article
Oncology
Brittney L. Dickey, Wenyi Fan, Deepti Bettampadi, Richard R. Reich, Bradley Sirak, Martha Abrahamsen, Maria Luiza Baggio, Lenice Galan, Roberto Carvalho Silva, Jorge Salmeron, Luisa L. Villa, Eduardo Lazcano-Ponce, Anna R. Giuliano
Summary: Research shows that men are at significantly higher risk of developing oral HPV infection of the same type after prior genital infection of the same type. Sequential infections present a higher risk, highlighting the importance of vaccination to prevent all HPV infections.
INTERNATIONAL JOURNAL OF CANCER
(2021)
Article
Oncology
Marjorie M. A. de Souza, Gunter Hartel, Catherine M. Olsen, David C. Whiteman, Annika Antonsson
Summary: This Australian-based study assessed the prevalence of oral HPV infection in Australian residents and found that the prevalence was 7.2%. The study also found a strong association between oral HPV infection and sexual behaviors, and suggested that HPV vaccination may result in a lower risk of infection with nonavalent HPV types.
INTERNATIONAL JOURNAL OF CANCER
(2023)
Article
Oncology
Annika Antonsson, Marjorie M. A. de Souza, Benedict J. Panizza, David C. Whiteman
Summary: Oropharyngeal cancer is increasingly caused by HPV, possibly due to changing sexual behavior. Sexual intercourse elicits a stronger immune response to HPV compared to oral sex, potentially leading to a weaker immune response in individuals who have their oral sex debut before or at the same time as sexual intercourse, increasing their risk of developing persistent oral HPV infection and oropharyngeal cancer.
INTERNATIONAL JOURNAL OF CANCER
(2022)
Article
Otorhinolaryngology
Barbara Kofler, Andreas Widschwendter, Benedikt Hofauer, Carina Gatt, Sophie Fabel, Anke Leichtle, Alexandra Ciresa-Koenig, Jozsef Dudas, Wegene Borena
Summary: This study investigated the relationship between genital HPV infection and undetected oropharyngeal HPV infection. The results showed a low rate of oropharyngeal HPV infection in the study population, with 2/142 (1.4%) women testing positive for a low-risk HPV genotype. In the genital brush test, 54/142 (38%) women tested positive for HPV, of which 41/142 (29%) were positive for a high-risk HPV genotype.
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
(2023)
Article
Immunology
Joseph E. Tota, Anna R. Giuliano, Stephen E. Goldstone, Brady Dubin, Alfred Saah, Alain Luxembourg, Christine Velicer, Joel M. Palefsky
Summary: The incidence of human papillomavirus (HPV)-related cancer is rising in men, and this study found that the prevalence of HPV infection and seropositivity is higher in men who have sex with men (MSM) compared to heterosexual men (HM). However, overall prevalence is still low. Catch-up vaccination after sexual debut may be beneficial.
CLINICAL INFECTIOUS DISEASES
(2022)
Article
Health Care Sciences & Services
Leticia Munoz-Hernando, Reyes Oliver-Perez, Victoria Bravo-Violeta, Alejandro Olloqui, Belen Parte-Izquierdo, Cristina Almansa-Gonzalez, Rocio Bermejo-Martinez, Ana Belen Bolivar-De Miguel, Alvaro Diez, Jose Miguel Seoane-Ruiz, Lucia Parrilla-Rubio, Alvaro Tejerizo-Garcia
Summary: This study analyzed the prevalence of anal high-risk HPV infection and abnormal anal cytology in women living with HIV, finding that concomitant HR-HPV cervical infection is the main predictor of HR-HPV anal infection.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Immunology
Lauri E. Markowitz, John T. Schiller
Summary: HPV vaccines are highly effective in preventing HPV-attributable cancers and have been introduced into national immunization programs in over 100 countries. The success of these vaccines has sparked interest in ambitious disease reduction goals.
JOURNAL OF INFECTIOUS DISEASES
(2021)
Article
Immunology
Abbey B. Berenson, Jacqueline M. Hirth, Mihyun Chang
Summary: The study found variations in penile HPV infection prevalence among US males by race/ethnicity and age, with Black males and older age groups exhibiting higher prevalence. Even after controlling for confounders, certain populations still showed significantly elevated HPV infection prevalence.
CLINICAL INFECTIOUS DISEASES
(2021)
Article
Infectious Diseases
Nelli T. Suominen, Anna J. Jaakola, Michel Roger, Marie-Claude Faucher, Kari J. Syrjanen, Seija E. Grenman, Stina M. Syrjanen, Karolina Louvanto
Summary: The study shows that the polymorphism of HLA-G plays a significant role in oral HPV infection in men, specific HLA-G alleles may affect infection and outcomes, while possibly being associated with self-reported allergies.
EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
(2022)
Article
Oncology
Annika Antonsson, Marjorie de Souza, Zoe C. Wood, Angela Carroll, Kim Van, Lachlan Paterson, Nirmala Pandeya, David C. Whiteman
Summary: Oral infection with HPV is likely to contribute to the increasing incidence of oropharyngeal squamous cell carcinoma, and is associated with sexual behaviors. New oral infections with HPV in the sample were not rare, with most infections being cleared but not universally, suggesting a reservoir of infection may predispose to oropharyngeal carcinogenesis.
INTERNATIONAL JOURNAL OF CANCER
(2021)
Article
Psychology, Developmental
Brittany L. Rosen, Pamina Gorbach, Lili Ding, Courtney Covert, Aaron C. Ermel, Emmanuel Chandler, Talia Malagon, Jessica A. Kahn
Summary: This study aimed to determine individual-and partner-level factors associated with HPV infection in vaccinated and unvaccinated men. The results showed that sexual network variables associated with HPV infection differed based on vaccination status and HPV type. Concurrent sexual relationships and characteristics of sexual partners were consistent risk factors for HPV infection.
JOURNAL OF ADOLESCENT HEALTH
(2021)
Article
Microbiology
Simon Blaine-Sauer, Myeong-Kyun Shin, Kristina A. Matkowskyj, Ella Ward-Shaw, Paul F. Lambert
Summary: This study demonstrates that MmuPV1 infection alone can efficiently mediate high-grade squamous intraepithelial lesions in the anal tract of mice using the NSG immunocompromised strain. We also show that MmuPV1, in combination with the chemical carcinogen DMBA, has carcinogenic potential. Furthermore, MmuPV1 is able to persist for up to 6 months in the anal tract of UVB-irradiated FVB/NJ mice and contributes to high-grade disease and cancer in an immunocompetent strain.
Article
Immunology
Cintia Munoz-Quiles, Monica Lopez-Lacort, Javier Diez-Domingo, Vallivana Rodrigo-Casares, Alejandro Orrico-Sanchez
Summary: This study aimed to assess the effectiveness of HPV vaccines in preventing genital warts in women. The results showed that a complete schedule of the quadrivalent HPV vaccine was 74% effective in reducing genital warts. The study also suggested indirect protection for unvaccinated and HPV2v vaccinated girls.
Review
Oncology
Kelsey H. Jordan, Chloe M. Beverly Hery, Xiaochen Zhang, Electra D. Paskett
Summary: The relationship between oral-cervical HPV infections/cancers is not well established and remains understudied. Previous research mainly consisted of cross-sectional studies, with most using synchronous testing methods and few reporting HPV type concordance. Most studies on HPV-related cancer diagnoses reported an increased risk of secondary cancer. Future research should utilize stronger methodologies and conduct HPV concordance analyses to better understand the epidemiology of oral-cervical HPV infections/cancers.
FRONTIERS IN ONCOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Yu Zhang, Ya Xu, Ziqin Dian, Guiqian Zhang, Xin Fan, Yuan Zhao, Yi Sun
Summary: This study investigated the prevalence and genotype distribution of HPV infection among outpatient-based populations. The results showed differences in the prevalence and genotype distribution of HPV infection among different outpatient populations, with the highest prevalence in gynecological outpatients. The most common HPV genotypes were HPV-52, 16, and 58. High prevalence of HPV infection was observed among women under 25 years and over 55 years.
FRONTIERS IN PUBLIC HEALTH
(2022)
Letter
Dermatology
Giulia Ciccarese, Francesco Drago, Samuele Boldrin, Matilde Pattaro, Aurora Parodi
DERMATOLOGIC THERAPY
(2022)
Article
Dermatology
Giulia Ciccarese, Aurora Parodi, Francesco Drago
Summary: This study investigated the efficacy of 5-fluorouracil 0.5%/salicylic acid 10% solution (5FU/SAsol) in the treatment of ano-genital warts (AGWs). The results showed that 88% of patients benefited from the treatment at 3 months and 94% at 6 months. 5FU/SAsol was well tolerated with minimal adverse events. The clearance rate after 3 months of treatment was comparable to other commonly used modalities.
DERMATOLOGIC THERAPY
(2022)
Letter
Dermatology
Giulia Ciccarese, Aurora Parodi, Francesco Drago
DERMATOLOGIC THERAPY
(2022)
Letter
Infectious Diseases
Francesco Drago, Francesco Broccolo, Giulia Ciccarese
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
(2022)
Letter
Virology
Giulia Ciccarese, Francesco Drago, Eugenio Marinaro, Aurora Parodi
JOURNAL OF MEDICAL VIROLOGY
(2022)
Review
Virology
Giulia Ciccarese, Francesco Drago, Francesco Broccolo, Angela Pastorino, Laura Pizzatti, Laura Atzori, Luca Pilloni, Davide Santinelli, Alice Urbani, Aurora Parodi, Carlo Tomasini, Franco Rongioletti
Summary: This study investigated the association between human oncoviruses and melanoma. The detection rate of oncoviruses (HPV, EBV, and herpesvirus 8DNA) was found to be higher in mucosal and ocular melanomas compared to cutaneous melanomas. This suggests that oncoviruses may act as cofactors in the development of certain types of melanoma.
JOURNAL OF MEDICAL VIROLOGY
(2023)
Letter
Dermatology
Giulia Ciccarese, Francesco Broccolo, Aurora Parodi, Francesco Drago
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
(2023)
Article
Immunology
Laura Labate, Giorgia Brucci, Giulia Ciccarese, Bianca Bruzzone, Valentina Ricucci, Federica Stefanelli, Emanuele Delfino, Lucia Taramasso, Matteo Bassetti, Antonio Di Biagio
Summary: A 25-year-old Brazilian man with concurrent diagnoses of acute HIV infection, primary syphilis, and monkeypox infection with a nasal lesion was successfully treated with intravenous cidofovir.
INTERNATIONAL JOURNAL OF STD & AIDS
(2023)
Letter
Dermatology
Andrea Carugno, Michele Parietti, Giulia Ciccarese, Anna Campanati, Federico Diotallevi, Laura Atzori, Riccardo Balestri, Stefano Caccavale, Francesco Bellinato, Simone Vasilij Benatti, Serena Venturelli, Pamela Vezzoli, Paolo Sena, Manuela Papini
JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
(2023)
Letter
Dermatology
Giulia Ciccarese, Mario Mastrolonardo, Gaetano Serviddio, Francesco Drago
JOURNAL OF COSMETIC DERMATOLOGY
(2023)
Letter
Public, Environmental & Occupational Health
Giulia Ciccarese, Giorgia Brucci, Antonio Di Biagio, Francesco Drago, Matilde Ogliastro, Bruno Caccianotti, Sergio Lo Caputo, Teresa Santantonio, Gaetano Serviddio
TRAVEL MEDICINE AND INFECTIOUS DISEASE
(2023)
Article
Medicine, General & Internal
Astrid Herzum, Corrado Occella, Lodovica Gariazzo, Carlotta Pastorino, Gianmaria Viglizzo
Summary: Corticophobia, the fear of using topical corticosteroids, is becoming a more prevalent issue in industrialized countries, despite the proven safety of these medications for treating atopic dermatitis. This study found that factors such as milder or moderate disease severity, older age of patients, earlier disease onset, and previous healthcare professional consultations were associated with parental corticophobia. Additionally, severe parental corticophobia was significantly associated with a higher level of parental education and a greater impact on parental quality of life. Assessing the risk factors for corticophobia is crucial for developing educational programs that address the concerns of high-risk parents, in order to alleviate unfounded fears and improve treatment adherence.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Medicine, General & Internal
Astrid Herzum, Giulia Ciccarese, Corrado Occella, Lodovica Gariazzo, Carlotta Pastorino, Ilaria Trave, Gianmaria Viglizzo
Summary: Treating anogenital warts in children is challenging, with limited approved treatments. Topical therapies, such as immunomodulating agents and cytotoxic agents, are considered safe and effective options. HPV vaccination may also have a potential therapeutic role.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Medicine, General & Internal
Astrid Herzum, Corrado Occella, Valerio Gaetano Vellone, Lodovica Gariazzo, Carlotta Pastorino, Jacopo Ferro, Angela Sementa, Katia Mazzocco, Nadia Vercellino, Gianmaria Viglizzo
Summary: This study conducted a retrospective survey on pediatric spitzoid lesions and found that the majority of these lesions were benign, but there were also atypical and malignant lesions. Therefore, caution is needed in handling these lesions.
