The Stress-Responsive microRNA-34a Alters Insulin Signaling and Actions in Adipocytes through Induction of the Tyrosine Phosphatase PTP1B

Adipose-tissue plasticity in health and disease

(2022) Alexander Sakers et al.   CELL

The role of protein tyrosine phosphatase 1B (PTP1B) in the pathogenesis of type 2 diabetes mellitus and its complications

(2022) Maryam Teimouri et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

Association of miR-34a and miR-143 levels with PPARγ gene expression in adipose tissues of non-diabetic adults

(2022) Maryam Zarkesh et al.   Journal of Physiological Anthropology

circ_CSNK1E modulates airway smooth muscle cells proliferation and migration via miR-34a-5p/VAMP2 axis in asthma

(2022) Ling Ding et al.   CELLULAR SIGNALLING

MiR-34a suppression targets Nampt to ameliorate bone marrow mesenchymal stem cell senescence by regulating NAD+-Sirt1 pathway

(2021) Chenchen Pi et al.   Stem Cell Research & Therapy

An Adipocyte Cell Culture Model to Study the Impact of Protein and Micro-RNA Modulation on Adipocyte Function

(2021) Jennifer Jager et al.   Jove-Journal of Visualized Experiments

Adipocyte, Immune Cells, and miRNA Crosstalk: A Novel Regulator of Metabolic Dysfunction and Obesity

(2021) Sonia Kiran et al.   Cells

Mechanisms of insulin resistance related to white, beige, and brown adipocytes

(2020) Michael P. Czech   Molecular Metabolism

An AMPK-dependent, non-canonical p53 pathway plays a key role in adipocyte metabolic reprogramming

(2020) Hong Wang et al.   eLife

Regulatory microRNAs in Brown, Brite and White Adipose Tissue

(2020) Seley Gharanei et al.   Cells

Adipocyte-secreted exosomal microRNA-34a inhibits M2 macrophage polarization to promote obesity-induced adipose inflammation

(2019) Yong Pan et al.   JOURNAL OF CLINICAL INVESTIGATION

MicroRNA-34 family: a potential tumor suppressor and therapeutic candidate in cancer

(2019) Lu Zhang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

miR-34a as hub of T cell regulation networks

(2019) Martin Hart et al.   Journal for ImmunoTherapy of Cancer

Extracellular signal-regulated kinase 1/2 regulates NAD metabolism during acute kidney injury through microRNA-34a-mediated NAMPT expression

(2019) Justin B. Collier et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Adipose-derived circulating miRNAs regulate gene expression in other tissues

(2017) Thomas Thomou et al.   NATURE

DNA Damage and the Activation of the p53 Pathway Mediate Alterations in Metabolic and Secretory Functions of Adipocytes

(2016) Bastien Vergoni et al.   DIABETES

MicroRNA mir-34 provides robustness to environmental stress response via the DAF-16 network in C. elegans

(2016) Meltem Isik et al.   Scientific Reports

NAMPT-Mediated NAD + Biosynthesis in Adipocytes Regulates Adipose Tissue Function and Multi-organ Insulin Sensitivity in Mice

(2016) Kelly L. Stromsdorfer et al.   Cell Reports

MicroRNA regulatory networks in human adipose tissue and obesity

(2015) Peter Arner et al.   Nature Reviews Endocrinology

Physiological and pathophysiological roles of NAMPT and NAD metabolism

(2015) Antje Garten et al.   Nature Reviews Endocrinology

Studies of the regulated assembly of SNARE complexes in adipocytes

(2014) Dimitrios Kioumourtzoglou et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

MicroRNA 34a Inhibits Beige and Brown Fat Formation in Obesity in Part by Suppressing Adipocyte Fibroblast Growth Factor 21 Signaling and SIRT1 Function

(2014) T. Fu et al.   MOLECULAR AND CELLULAR BIOLOGY

The p53/miR-34 axis in development and disease

(2014) M. Rokavec et al.   Journal of Molecular Cell Biology

Elevated microRNA-34a in obesity reduces NAD+levels and SIRT1 activity by directly targeting NAMPT

(2013) Sung-E Choi et al.   AGING CELL

Adipose tissue dysfunction contributes to obesity related metabolic diseases

(2013) Matthias Blüher   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

MicroRNAs and Metabolism Crosstalk in Energy Homeostasis

(2013) Olivier Dumortier et al.   Cell Metabolism

Implication of inflammatory signaling pathways in obesity-induced insulin resistance

(2013) Jean-François Tanti et al.   Frontiers in Endocrinology

Regulation of Glucose Transporter Translocation in Health and Diabetes

(2012) Jonathan S. Bogan   Annual Review of Biochemistry

Adipose Tissue MicroRNAs as Regulators of CCL2 Production in Human Obesity

(2012) E. Arner et al.   DIABETES

MicroRNAs in Insulin Resistance and Obesity

(2012) Michael D. Williams et al.   Experimental Diabetes Research

MicroRNAs in adipose tissue: their role in adipogenesis and obesity

(2012) C Hilton et al.   INTERNATIONAL JOURNAL OF OBESITY

Correction: Adipocyte-Specific Protein Tyrosine Phosphatase 1B Deletion Increases Lipogenesis, Adipocyte Cell Size and Is a Minor Regulator of Glucose Homeostasis

(2012) Carl Owen et al.   PLoS One

Therapeutic inhibition of the miR-34 family attenuates pathological cardiac remodeling and improves heart function

(2012) B. C. Bernardo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nicotinamide Mononucleotide, a Key NAD+ Intermediate, Treats the Pathophysiology of Diet- and Age-Induced Diabetes in Mice

(2011) Jun Yoshino et al.   Cell Metabolism

MicroRNAs 103 and 107 regulate insulin sensitivity

(2011) Mirko Trajkovski et al.   NATURE

The Secret Life of NAD+: An Old Metabolite Controlling New Metabolic Signaling Pathways

(2010) Riekelt H. Houtkooper et al.   ENDOCRINE REVIEWS

MicroRNA Functions in Stress Responses

(2010) Anthony K.L. Leung et al.   MOLECULAR CELL

MiRNA Expression Profile of Human Subcutaneous Adipose and during Adipocyte Differentiation

(2010) Francisco J. Ortega et al.   PLoS One

The t-SNAREs syntaxin4 and SNAP23 but not v-SNARE VAMP2 are indispensable to tether GLUT4 vesicles at the plasma membrane in adipocyte

(2009) Takayuki Kawaguchi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cellular mechanisms of insulin resistance: role of stress-regulated serine kinases and insulin receptor substrates (IRS) serine phosphorylation

(2009) Jean-François Tanti et al.   CURRENT OPINION IN PHARMACOLOGY

Involvement of TNF-α in abnormal adipocyte and muscle sortilin expression in obese mice and humans

(2009) V. Kaddai et al.   DIABETOLOGIA

A crucial role for adipose tissue p53 in the regulation of insulin resistance

(2009) Tohru Minamino et al.   NATURE MEDICINE

SIRT1 and insulin resistance

(2009) Fengxia Liang et al.   Nature Reviews Endocrinology

The nitric oxide-donating derivative of acetylsalicylic acid, NCX 4016, stimulates glucose transport and glucose transporters translocation in 3T3-L1 adipocytes

(2008) V. Kaddai et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Liver-Specific Deletion of Protein-Tyrosine Phosphatase 1B (PTP1B) Improves Metabolic Syndrome and Attenuates Diet-Induced Endoplasmic Reticulum Stress

(2008) M. Delibegovic et al.   DIABETES

Alterations in MicroRNA Expression Contribute to Fatty Acid-Induced Pancreatic  -Cell Dysfunction

(2008) P. Lovis et al.   DIABETES

Protein-tyrosine Phosphatase 1B Expression Is Induced by Inflammationin Vivo

(2008) Janice M. Zabolotny et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SIRT1 Exerts Anti-Inflammatory Effects and Improves Insulin Sensitivity in Adipocytes

(2008) T. Yoshizaki et al.   MOLECULAR AND CELLULAR BIOLOGY