Potent In Vitro and Ex Vivo Anti-Gonococcal Activity of the RpoB Inhibitor Corallopyronin A
出版年份 2022 全文链接
标题
Potent
In Vitro
and
Ex Vivo
Anti-Gonococcal Activity of the RpoB Inhibitor Corallopyronin A
作者
关键词
-
出版物
mSphere
Volume 7, Issue 5, Pages -
出版商
American Society for Microbiology
发表日期
2022-09-12
DOI
10.1128/msphere.00362-22
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- The European response to control and manage multi- and extensively drug-resistant Neisseria gonorrhoeae
- (2022) Michelle J Cole et al. Eurosurveillance
- Gonococcal Clinical Strains Bearing a Common gdhR Single Nucleotide Polymorphism That Results in Enhanced Expression of the Virulence Gene lctP Frequently Possess a mtrR Promoter Mutation That Decreases Antibiotic Susceptibility
- (2022) Julio C. Ayala et al. mBio
- Pharmacodynamic Evaluation of Zoliflodacin Treatment of Neisseria gonorrhoeae Strains With Amino Acid Substitutions in the Zoliflodacin Target GyrB Using a Dynamic Hollow Fiber Infection Model
- (2022) Susanne Jacobsson et al. Frontiers in Pharmacology
- Rifampicin Resistance Associated with rpoB Mutations in Neisseria gonorrhoeae Clinical Strains Isolated in Austria, 2016 to 2020
- (2022) Justine Schaeffer et al. Microbiology Spectrum
- The RNA Polymerase Inhibitor Corallopyronin A Has a Lower Frequency of Resistance Than Rifampicin in Staphylococcus aureus
- (2022) Jan Balansky et al. Antibiotics-Basel
- Structures of Neisseria gonorrhoeae MtrR-operator complexes reveal molecular mechanisms of DNA recognition and antibiotic resistance-conferring clinical mutations
- (2021) Grace A Beggs et al. NUCLEIC ACIDS RESEARCH
- A drug candidate for Alzheimer’s and Huntington’s disease, PBT2, can be repurposed to render Neisseria gonorrhoeae susceptible to natural cationic antimicrobial peptides
- (2021) Freda E -C Jen et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Preclinical Testing of Vaccines and Therapeutics for Gonorrhea in Female Mouse Models of Lower and Upper Reproductive Tract Infection
- (2021) Kristie L Connolly et al. JOURNAL OF INFECTIOUS DISEASES
- Repurposing FDA-approved sulphonamide carbonic anhydrase inhibitors for treatment of Neisseria gonorrhoeae
- (2021) Nader S. Abutaleb et al. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
- Repurposed Drugs That Block the Gonococcus-Complement Receptor 3 Interaction Can Prevent and Cure Gonococcal Infection of Primary Human Cervical Epithelial Cells
- (2020) Jessica Poole et al. mBio
- Repurposing fenamic acids drugs to combat multidrug-resistant Neisseria gonorrhoeae
- (2020) Young Jin Seong et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Corallopyronin A for short-course anti-wolbachial, macrofilaricidal treatment of filarial infections
- (2020) Andrea Schiefer et al. PLoS Neglected Tropical Diseases
- Update to CDC's Treatment Guidelines for Gonococcal Infection, 2020
- (2020) Sancta St. Cyr et al. MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT
- Solubility and Stability Enhanced Oral Formulations for the Anti-Infective Corallopyronin A
- (2020) Anna K. Krome et al. Pharmaceutics
- Elaborations on Corallopyronin A as a Novel Treatment Strategy Against Genital Chlamydial Infections
- (2019) Nathalie Loeper et al. Frontiers in Microbiology
- Repurposing salicylamide for combating multidrug-resistant Neisseria gonorrhoeae
- (2019) Marwa Alhashimi et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Production optimization and biosynthesis revision of corallopyronin A, a potent anti-filarial antibiotic
- (2019) Domen Pogorevc et al. METABOLIC ENGINEERING
- The first wide‐scale drug repurposing screen using the Prestwick Chemical Library (1200 bioactive molecules) against Neisseria gonorrhoeae identifies high in vitro activity of auranofin and many additional drugs
- (2019) Sunniva Foerster et al. APMIS
- Antimicrobial resistance in sexually transmitted infections
- (2019) Vivian Tien et al. JOURNAL OF TRAVEL MEDICINE
- Orientia tsutsugamushi Is Highly Susceptible to the RNA Polymerase Switch Region Inhibitor Corallopyronin A In Vitro and In Vivo
- (2018) Fredericke Kock et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Gepotidacin for the Treatment of Uncomplicated Urogenital Gonorrhea: A Phase 2, Randomized, Dose-Ranging, Single-Oral Dose Evaluation
- (2018) Stephanie N Taylor et al. CLINICAL INFECTIOUS DISEASES
- Effective inhibition of rifampicin-resistant Chlamydia trachomatis by the novel DNA-dependent RNA polymerase inhibitor corallopyronin A
- (2018) Kensuke Shima et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- Single-Dose Zoliflodacin (ETX0914) for Treatment of Urogenital Gonorrhea
- (2018) Stephanie N. Taylor et al. NEW ENGLAND JOURNAL OF MEDICINE
- Heterologous production of myxobacterial α-pyrone antibiotics in Myxococcus xanthus
- (2017) Hilda Sucipto et al. METABOLIC ENGINEERING
- The novel 2016 WHONeisseria gonorrhoeaereference strains for global quality assurance of laboratory investigations: phenotypic, genetic and reference genome characterization
- (2016) Magnus Unemo et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Importance of Multidrug Efflux Pumps in the Antimicrobial Resistance Property of Clinical Multidrug-Resistant Isolates of Neisseria gonorrhoeae
- (2014) Daniel Golparian et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Antimicrobial Resistance in Neisseria gonorrhoeae in the 21st Century: Past, Evolution, and Future
- (2014) M. Unemo et al. CLINICAL MICROBIOLOGY REVIEWS
- Corallopyronin A – A promising antibiotic for treatment of filariasis
- (2013) Till F. Schäberle et al. INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY
- Corallopyronin A Specifically Targets and Depletes Essential Obligate Wolbachia Endobacteria From Filarial Nematodes In Vivo
- (2012) Andrea Schiefer et al. JOURNAL OF INFECTIOUS DISEASES
- Activity of and Development of Resistance to Corallopyronin A, an Inhibitor of RNA Polymerase
- (2011) Katherine Mariner et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- TheNeisseria gonorrhoeaeBiofilm Matrix Contains DNA, and an Endogenous Nuclease Controls Its Incorporation
- (2011) Christopher T. Steichen et al. INFECTION AND IMMUNITY
- The RNA Polymerase “Switch Region” Is a Target for Inhibitors
- (2008) Jayanta Mukhopadhyay et al. CELL
- MtrR Modulates rpoH Expression and Levels of Antimicrobial Resistance in Neisseria gonorrhoeae
- (2008) J. P. Folster et al. JOURNAL OF BACTERIOLOGY
- Gonococcal Cervicitis: A Role for Biofilm in Pathogenesis
- (2008) Christopher T. Steichen et al. JOURNAL OF INFECTIOUS DISEASES
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