NCOA4-mediated ferritinophagy is involved in ionizing radiation-induced ferroptosis of intestinal epithelial cells

Ferroptosis plays an important role in promoting ionizing radiation-induced intestinal injuries

(2022) Lei Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Hematopoietic protection and mechanisms of ferrostatin-1 on hematopoietic acute radiation syndrome of mice

(2021) Xiaohong Zhang et al.   INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Ferroptosis: mechanisms, biology and role in disease

(2021) Xuejun Jiang et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Ferroptosis as a mechanism to mediate p53 function in tumor radiosensitivity

(2021) Guang Lei et al.   ONCOGENE

Autophagy in major human diseases

(2021) Daniel J Klionsky et al.   EMBO JOURNAL

Mitochondrial regulation of ferroptosis

(2021) Boyi Gan   JOURNAL OF CELL BIOLOGY

Iron-Dependent Autophagic Cell Death Induced by Radiation in MDA-MB-231 Breast Cancer Cells

(2021) Shumei Ma et al.   Frontiers in Cell and Developmental Biology

Radiation-Induced Lipid Peroxidation Triggers Ferroptosis and Synergizes with Ferroptosis Inducers

(2020) Ling F. Ye et al.   ACS Chemical Biology

The role of ferroptosis in ionizing radiation-induced cell death and tumor suppression

(2020) Guang Lei et al.   CELL RESEARCH

Ionizing radiation induces ferroptosis in granulocyte-macrophage hematopoietic progenitor cells of murine bone marrow

(2020) Xiaohong Zhang et al.   INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Anti-Ferroptosis Drug Enhances Total-Body Irradiation Mitigation by Drugs that Block Apoptosis and Necroptosis

(2020) Stephanie Thermozier et al.   RADIATION RESEARCH

Biomaterials and biosensors in intestinal organoid culture, a progress review

(2020) Jinjian Huang et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Transferrin Receptor Is a Specific Ferroptosis Marker

(2020) Huizhong Feng et al.   Cell Reports

Ferroptosis: molecular mechanisms and health implications

(2020) Daolin Tang et al.   CELL RESEARCH

Green tea derivative (−)-epigallocatechin-3-gallate (EGCG) confers protection against ionizing radiation-induced intestinal epithelial cell death both in vitro and in vivo

(2020) Li-Wei Xie et al.   FREE RADICAL BIOLOGY AND MEDICINE

Ferroptosis inhibitor alleviates Radiation-induced lung fibrosis (RILF) via down-regulation of TGF-β1

(2019) Xuan Li et al.   Journal of Inflammation-London

Essential and Detrimental – an Update on Intracellular Iron Trafficking and Homeostasis

(2019) Gianpiero Vigani et al.   PLANT AND CELL PHYSIOLOGY

Role of ferroptosis in the process of acute radiation-induced lung injury in mice

(2019) Xuan Li et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mitochondria regulation in ferroptosis

(2019) Hai Wang et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

The effects of iron overload on mitochondrial function, mitochondrial dynamics, and ferroptosis in cardiomyocytes

(2019) Natticha Sumneang et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Radiation-induced intestinal damage: latest molecular and clinical developments

(2019) Lina Lu et al.   Future Oncology

Identification of Circular RNAs Altered in Mouse Jejuna After Radiation

(2018) Qianying Lu et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Mitochondrial function — gatekeeper of intestinal epithelial cell homeostasis

(2018) Eva Rath et al.   Nature Reviews Gastroenterology & Hepatology

Role of Mitochondria in Ferroptosis

(2018) Minghui Gao et al.   MOLECULAR CELL

Interplay between metabolic identities in the intestinal crypt supports stem cell function

(2017) Maria J. Rodríguez-Colman et al.   NATURE

Autophagy promotes ferroptosis by degradation of ferritin

(2016) Wen Hou et al.   Autophagy

Ferroptosis is an autophagic cell death process

(2016) Minghui Gao et al.   CELL RESEARCH

Inhibition of CDK4/6 protects against radiation-induced intestinal injury in mice

(2016) Liang Wei et al.   JOURNAL OF CLINICAL INVESTIGATION

High dietary iron increases oxidative stress and radiosensitivity in the rat retina and vasculature after exposure to fractionated gamma radiation

(2016) Corey A Theriot et al.   NPJ Microgravity

Lentiviral DDX46 knockdown inhibits growth and induces apoptosis in human colorectal cancer cells

(2015) Ming Li et al.   GENE

Krüppel-Like Factor 5 Promotes Epithelial Proliferation and DNA Damage Repair in the Intestine of Irradiated Mice

(2015) Ming Li et al.   International Journal of Biological Sciences

Iron regulatory proteins and their role in controlling iron metabolism

(2015) Lukas C. Kühn   Metallomics

Ferritinophagy via NCOA4 is required for erythropoiesis and is regulated by iron dependent HERC2-mediated proteolysis

(2015) Joseph D Mancias et al.   eLife

Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy

(2014) Joseph D. Mancias et al.   NATURE

Radiation enteropathy—pathogenesis, treatment and prevention

(2014) Martin Hauer-Jensen et al.   Nature Reviews Gastroenterology & Hepatology

Lgr5+ Stem Cells Are Indispensable for Radiation-Induced Intestinal Regeneration

(2013) Ciara Metcalfe et al.   Cell Stem Cell

Increased dietary iron and radiation in rats promote oxidative stress, induce localized and systemic immune system responses, and alter colon mucosal environment

(2013) Jennifer L. L. Morgan et al.   FASEB JOURNAL

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

Intranasal delivery of deferoxamine reduces spatial memory loss in APP/PS1 mice

(2012) Leah R. Hanson et al.   Drug Delivery and Translational Research

The convergence of radiation and immunogenic cell death signaling pathways

(2012) Encouse B. Golden et al.   Frontiers in Oncology

Bid mediates fission, membrane permeabilization and peri-nuclear accumulation of mitochondria as a prerequisite for oxidative neuronal cell death

(2009) Julia Grohm et al.   BRAIN BEHAVIOR AND IMMUNITY