Ocular barriers as a double-edged sword: preventing and facilitating drug delivery to the retina
出版年份 2022 全文链接
标题
Ocular barriers as a double-edged sword: preventing and facilitating drug delivery to the retina
作者
关键词
-
出版物
Drug Delivery and Translational Research
Volume -, Issue -, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2022-09-21
DOI
10.1007/s13346-022-01231-5
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Survival of an HLA-mismatched, bioengineered RPE implant in dry age-related macular degeneration
- (2022) Amir H. Kashani et al. Stem Cell Reports
- Synthetic high-density lipoprotein nanoparticles delivering rapamycin for the treatment of age-related macular degeneration
- (2022) Ling Mei et al. Nanomedicine-Nanotechnology Biology and Medicine
- Endothelial Unc5B controls blood-brain barrier integrity
- (2022) Kevin Boyé et al. Nature Communications
- Retinal Diseases: The Next Frontier in Pharmacodelivery
- (2022) Assaf Ben-Arzi et al. Pharmaceutics
- Suprachoroidal versus Intravitreal Triamcinolone Acetonide for the Treatment of Diabetic Macular Edema
- (2022) Yousra Gamal Zakaria et al. Clinical Ophthalmology
- Ocular Gene Therapy: A Literature Review with Special Focus on Immune and Inflammatory Responses
- (2022) Hashem H Ghoraba et al. Clinical Ophthalmology
- Modified Microneedle for Suprachoroidal Injection of Triamcinolone Acetonide Combined with Intravitreal Injection of Ranibizumab in Branch Retinal Vein Occlusion Patients
- (2022) Amin E Nawar Clinical Ophthalmology
- Angiographic findings before and after the onset of brolucizumab-associated retinal vascular occlusion and intraocular inflammation
- (2022) Sentaro Kusuhara et al. American Journal of Ophthalmology Case Reports
- Three‐Year Safety Results of SAR422459 (EIAV‐ABCA4) Gene Therapy in Patients With ABCA4‐Associated Stargardt Disease: An Open‐Label Dose‐Escalation Phase I/IIa Clinical Trial, Cohorts 1‐5
- (2022) Maria A. Parker et al. AMERICAN JOURNAL OF OPHTHALMOLOGY
- AAV2-hCHM Subretinal Delivery to the Macula in Choroideremia: Two Year Interim Results of an Ongoing Phase I/II Gene Therapy Trial
- (2022) Tomas S. Aleman et al. OPHTHALMOLOGY
- Ocular Drug Delivery to the Retina: Current Innovations and Future Perspectives
- (2021) Hyeong Min Kim et al. Pharmaceutics
- Extension study of the safety and efficacy of CLS-TA for treatment of macular oedema associated with non-infectious uveitis (MAGNOLIA)
- (2021) Rahul N Khurana et al. BRITISH JOURNAL OF OPHTHALMOLOGY
- A phase I clinical trial of human embryonic stem cell‐derived retinal pigment epithelial cells for early‐stage Stargardt macular degeneration: 5‐years' follow‐up
- (2021) Shi‐Ying Li et al. CELL PROLIFERATION
- Ten Years of Knowledge of Nano-Carrier Based Drug Delivery Systems in Ophthalmology: Current Evidence, Challenges, and Future Prospective
- (2021) Jie Zhang et al. International Journal of Nanomedicine
- Vascular Endothelial Growth Factor Antagonists: Promising Players in the Treatment of Neovascular Age-Related Macular Degeneration
- (2021) Rehan M Hussain et al. Drug Design Development and Therapy
- Evaluation of Long-Lasting Potential of Suprachoroidal Axitinib Suspension Via Ocular and Systemic Disposition in Rabbits
- (2021) Viral S. Kansara et al. Translational Vision Science & Technology
- The Emerging Role of Topical Ocular Drugs to Target the Posterior Eye
- (2021) Lixiang Wang et al. Ophthalmology and Therapy
- The safety and efficacy of gene therapy treatment for monogenic retinal and optic nerve diseases: A systematic review
- (2021) Alexis Ceecee Britten-Jones et al. GENETICS IN MEDICINE
- Risk Mitigation of Immunogenicity: A Key to Personalized Retinal Gene Therapy
- (2021) Juliette Varin et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Intravenous route to choroidal neovascularization by macrophage-disguised nanocarriers for mTOR modulation
- (2021) Weiyi Xia et al. Acta Pharmaceutica Sinica B
- First-in-Human Robot-Assisted Subretinal Drug Delivery Under Local Anesthesia
- (2021) Jasmina Cehajic-Kapetanovic et al. AMERICAN JOURNAL OF OPHTHALMOLOGY
- Archway Randomized Phase 3 Trial of the Port Delivery System with Ranibizumab for Neovascular Age-Related Macular Degeneration
- (2021) Nancy M. Holekamp et al. OPHTHALMOLOGY
- Advances in ocular drug delivery systems
- (2020) Jennifer J. Kang-Mieler et al. EYE
- Initial results from a first-in-human gene therapy trial on X-linked retinitis pigmentosa caused by mutations in RPGR
- (2020) Jasmina Cehajic-Kapetanovic et al. NATURE MEDICINE
- Efficacy and Safety of Suprachoroidal CLS-TA for Macular Edema Secondary to Noninfectious Uveitis: Phase 3, Randomized Trial
- (2020) Steven Yeh et al. OPHTHALMOLOGY
- Suprachoroidal and Subretinal Injections of AAV Using Transscleral Microneedles for Retinal Gene Delivery in Nonhuman Primates
- (2020) Glenn Yiu et al. Molecular Therapy-Methods & Clinical Development
- L-Type amino acid transporter 1 as a target for drug delivery
- (2020) Elena Puris et al. PHARMACEUTICAL RESEARCH
- Real-Life Management of Diabetic Macular Edema with Dexamethasone Intravitreal Implant: A Retrospective Analysis of Long-Term Clinical Outcomes
- (2020) Massimo Nicolò et al. Journal of Ophthalmology
- Safety and Vision Outcomes of Subretinal Gene Therapy Targeting Cone Photoreceptors in Achromatopsia
- (2020) M. Dominik Fischer et al. JAMA Ophthalmology
- Long-term safety and tolerability of subretinal transplantation of embryonic stem cell-derived retinal pigment epithelium in Asian Stargardt disease patients
- (2020) Youngje Sung et al. BRITISH JOURNAL OF OPHTHALMOLOGY
- Nanoparticulate Drug Delivery to the Retina
- (2020) Qingqing Li et al. MOLECULAR PHARMACEUTICS
- Umbilical cord derived mesenchymal stem cell implantation in retinitis pigmentosa: a 6-month follow-up results of a phase 3 trial
- (2020) Neslihan Sinim Kahraman International Journal of Ophthalmology
- Causes of blindness and vision impairment in 2020 and trends over 30 years, and prevalence of avoidable blindness in relation to VISION 2020: the Right to Sight: an analysis for the Global Burden of Disease Study
- (2020) Jaimie D Steinmetz et al. Lancet Global Health
- Luxturna: FDA documents reveal the value of a costly gene therapy
- (2019) Jonathan J. Darrow DRUG DISCOVERY TODAY
- Three-year follow-up of Phase 1 and 2a rAAV.sFLT-1 subretinal gene therapy trials for exudative age related macular degeneration
- (2019) E.P. Rakoczy et al. AMERICAN JOURNAL OF OPHTHALMOLOGY
- Ocular Drug Delivery: Present Innovations and Future Challenges.
- (2019) Vrinda Gote et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Transplantation of Human Embryonic Stem Cell-Derived Retinal Tissue in the Subretinal Space of the Cat Eye
- (2019) Ratnesh K. Singh et al. STEM CELLS AND DEVELOPMENT
- Pharmacokinetics of Intravitreal Anti-VEGF Drugs in Age-Related Macular Degeneration
- (2019) Laura García-Quintanilla et al. Pharmaceutics
- Retinal stem cell transplantation: Balancing safety and potential
- (2019) Mandeep S. Singh et al. PROGRESS IN RETINAL AND EYE RESEARCH
- AAV8-vectored suprachoroidal gene transfer produces widespread ocular transgene expression
- (2019) Kun Ding et al. JOURNAL OF CLINICAL INVESTIGATION
- Submacular Injection of Ranibizumab as a New Surgical Treatment for Refractory Diabetic Macular Edema
- (2019) Samir M. El-Baha et al. Journal of Ophthalmology
- Influence of Charge, Hydrophobicity, and Size on Vitreous Pharmacokinetics of Large Molecules
- (2019) Susan R. Crowell et al. Translational Vision Science & Technology
- Collagenase injection into the suprachoroidal space of the eye to expand drug delivery coverage and increase posterior drug targeting
- (2019) Jae Hwan Jung et al. EXPERIMENTAL EYE RESEARCH
- Implications of melanin binding in ocular drug delivery
- (2018) Anna-Kaisa Rimpelä et al. ADVANCED DRUG DELIVERY REVIEWS
- The suprachoroidal space as a route of administration to the posterior segment of the eye
- (2018) Bryce Chiang et al. ADVANCED DRUG DELIVERY REVIEWS
- Recent advances in drug and nutrient transport across the blood-retinal barrier
- (2018) Yoshiyuki Kubo et al. Expert Opinion on Drug Metabolism & Toxicology
- Ocular drug delivery targeted by iontophoresis in the suprachoroidal space using a microneedle
- (2018) Jae Hwan Jung et al. JOURNAL OF CONTROLLED RELEASE
- Melanin targeting for intracellular drug delivery: Quantification of bound and free drug in retinal pigment epithelial cells
- (2018) Anna-Kaisa Rimpelä et al. JOURNAL OF CONTROLLED RELEASE
- Design of Hollow Hyaluronic Acid Cylinders for Sustained Intravitreal Protein Delivery
- (2018) Erik Van Kampen et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Binding of Small Molecule Drugs to Porcine Vitreous Humor
- (2018) Anna-Kaisa Rimpelä et al. MOLECULAR PHARMACEUTICS
- Phase 1 clinical study of an embryonic stem cell–derived retinal pigment epithelium patch in age-related macular degeneration
- (2018) Lyndon da Cruz et al. NATURE BIOTECHNOLOGY
- The expanding role of prodrugs in contemporary drug design and development
- (2018) Jarkko Rautio et al. NATURE REVIEWS DRUG DISCOVERY
- Transplantation of Human Embryonic Stem Cell-Derived Retinal Pigment Epithelial Cells in Macular Degeneration
- (2018) Manjit S. Mehat et al. OPHTHALMOLOGY
- Choroideremia Gene Therapy Phase 2 Clinical Trial: 24-Month Results
- (2018) Byron L. Lam et al. AMERICAN JOURNAL OF OPHTHALMOLOGY
- Folic acid-conjugated mesoporous silica nanoparticles for enhanced therapeutic efficacy of topotecan in retina cancers
- (2018) Wei Qu et al. International Journal of Nanomedicine
- SUPRACHOROIDAL INJECTION OF TRIAMCINOLONE ACETONIDE, CLS-TA, FOR MACULAR EDEMA DUE TO NONINFECTIOUS UVEITIS
- (2018) Steven Yeh et al. RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES
- Suprachoroidal Adipose Tissue-Derived Mesenchymal Stem Cell Implantation in Patients with Dry-Type Age-Related Macular Degeneration and Stargardt's Macular Dystrophy: 6-Month Follow-Up Results of a Phase 2 Study
- (2018) Ayse Oner et al. Cellular Reprogramming
- Understanding Molecular Drivers of Melanin Binding To Support Rational Design of Small Molecule Ophthalmic Drugs
- (2018) Paulina Jakubiak et al. JOURNAL OF MEDICINAL CHEMISTRY
- Evaluation of Dose and Safety of AAV7m8 and AAV8BP2 in the Non-Human Primate Retina
- (2017) Pavitra S. Ramachandran et al. HUMAN GENE THERAPY
- Efficacy and safety of voretigene neparvovec (AAV2-hRPE65v2) in patients with RPE65 -mediated inherited retinal dystrophy: a randomised, controlled, open-label, phase 3 trial
- (2017) Stephen Russell et al. LANCET
- Subretinal Injection: A Review on the Novel Route of Therapeutic Delivery for Vitreoretinal Diseases
- (2017) Yingqian Peng et al. OPHTHALMIC RESEARCH
- Caveolins and caveolae in ocular physiology and pathophysiology
- (2017) Xiaowu Gu et al. PROGRESS IN RETINAL AND EYE RESEARCH
- A New Method of Subretinal Injection of Tissue Plasminogen Activator and Air in Patients With Submacular Hemorrhage
- (2017) Fernando J. D. Novelli et al. RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES
- Photo-Modulated Therapeutic Protein Release from a Hydrogel Depot Using Visible Light
- (2016) Johan S. Basuki et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Hyperthermia of magnetic nanoparticles allows passage of sodium fluorescein and Evans blue dye across the blood–retinal barrier
- (2016) Seyed Nasrollah Tabatabaei et al. INTERNATIONAL JOURNAL OF HYPERTHERMIA
- Light activated liposomes: Functionality and prospects in ocular drug delivery
- (2016) Tatu Lajunen et al. JOURNAL OF CONTROLLED RELEASE
- A Minireview: Usefulness of Transporter-Targeted Prodrugs in Enhancing Membrane Permeability
- (2016) Teruo Murakami JOURNAL OF PHARMACEUTICAL SCIENCES
- Drug Distribution to Retinal Pigment Epithelium: Studies on Melanin Binding, Cellular Kinetics, and Single Photon Emission Computed Tomography/Computed Tomography Imaging
- (2016) Anna-Kaisa Rimpelä et al. MOLECULAR PHARMACEUTICS
- Stimuli-Responsive Polymeric Systems for Controlled Protein and Peptide Delivery: Future Implications for Ocular Delivery
- (2016) Pakama Mahlumba et al. MOLECULES
- In vivo and in vitro sustained release of ranibizumab from a nanoporous thin-film device
- (2016) Kevin D. Lance et al. Drug Delivery and Translational Research
- Diffusion Regulation in the Vitreous Humor
- (2015) Benjamin Tillmann Käsdorf et al. BIOPHYSICAL JOURNAL
- Electro-responsive macroporous polypyrrole scaffolds for triggered dexamethasone delivery
- (2015) A. Seyfoddin et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- High-Throughput Melanin-Binding Affinity and In Silico Methods to Aid in the Prediction of Drug Exposure in Ocular Tissue
- (2015) John Reilly et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Human embryonic stem cell-derived retinal pigment epithelium in patients with age-related macular degeneration and Stargardt's macular dystrophy: follow-up of two open-label phase 1/2 studies
- (2015) Steven D Schwartz et al. LANCET
- The immune response of stem cells in subretinal transplantation
- (2015) Bikun Xian et al. Stem Cell Research & Therapy
- Understanding photoreceptor outer segment phagocytosis: Use and utility of RPE cells in culture
- (2014) Francesca Mazzoni et al. EXPERIMENTAL EYE RESEARCH
- Particle-Stabilized Emulsion Droplets for Gravity-Mediated Targeting in the Posterior Segment of the Eye
- (2014) Yoo C. Kim et al. Advanced Healthcare Materials
- Global prevalence of age-related macular degeneration and disease burden projection for 2020 and 2040: a systematic review and meta-analysis
- (2014) Wan Ling Wong et al. Lancet Global Health
- Implantable MicroPump for Drug Delivery in Patients with Diabetic Macular Edema
- (2014) Mark Humayun et al. Translational Vision Science & Technology
- One-Year Feasibility Study of Replenish MicroPump for Intravitreal Drug Delivery: A Pilot Study
- (2014) Juan-Carlos Gutiérrez-Hernández et al. Translational Vision Science & Technology
- Hyaluronan-modified core–shell liponanoparticles targeting CD44-positive retinal pigment epithelium cells via intravitreal injection
- (2013) Li Gan et al. BIOMATERIALS
- β-Alanine and l-histidine transport across the inner blood-retinal barrier: Potential involvement in l-carnosine supply
- (2013) Takuya Usui et al. EXPERIMENTAL EYE RESEARCH
- Nanoparticle diffusion in, and microrheology of, the bovine vitreous ex vivo
- (2013) Qingguo Xu et al. JOURNAL OF CONTROLLED RELEASE
- Effect of Choroidal Perfusion on Ocular Tissue Distribution After Intravitreal or Suprachoroidal Injection in an Arterially Perfused Ex Vivo Pig Eye Model
- (2013) Eva M. Abarca et al. JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS
- Size-dependent internalisation of folate-decorated nanoparticles via the pathways of clathrin and caveolae-mediated endocytosis in ARPE-19 cells
- (2013) Wai-Leung Langston Suen et al. JOURNAL OF PHARMACY AND PHARMACOLOGY
- In Vitro, In Vivo, and In Silico Evaluation of the Bioresponsive Behavior of an Intelligent Intraocular Implant
- (2013) Lisa C. du Toit et al. PHARMACEUTICAL RESEARCH
- Global Prevalence and Major Risk Factors of Diabetic Retinopathy
- (2012) J. W. Y. Yau et al. DIABETES CARE
- Gene Expression Profiling of Transporters in the Solute Carrier and ATP-Binding Cassette Superfamilies in Human Eye Substructures
- (2012) Amber Dahlin et al. MOLECULAR PHARMACEUTICS
- Nanostructured Thin Film Polymer Devices for Constant-Rate Protein Delivery
- (2012) Daniel A. Bernards et al. NANO LETTERS
- Safety of Submacular Suprachoroidal Drug Administration via a Microcatheter: Retrospective Analysis of European Treatment Results
- (2012) Manfred Tetz et al. OPHTHALMOLOGICA
- Targeted and Reversible Blood-Retinal Barrier Disruption via Focused Ultrasound and Microbubbles
- (2012) Juyoung Park et al. PLoS One
- Comparison of Suprachoroidal Drug Delivery with Subconjunctival and Intravitreal Routes Using Noninvasive Fluorophotometry
- (2012) Puneet Tyagi et al. PLoS One
- PHARMACOKINETIC COMPARISON OF KETOROLAC AFTER INTRACAMERAL, INTRAVITREAL, AND SUPRACHOROIDAL ADMINISTRATION IN RABBITS
- (2012) MeiZi Wang et al. RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES
- Systemic low-molecular weight drug delivery to pre-selected neuronal regions
- (2011) Matthew Campbell et al. EMBO Molecular Medicine
- Comparison of Drug Permeabilities Across the Blood–Retinal Barrier, Blood–Aqueous Humor Barrier, and Blood–Brain Barrier
- (2011) Ryotaro Toda et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Long-term Benefit of Sustained-Delivery Fluocinolone Acetonide Vitreous Inserts for Diabetic Macular Edema
- (2011) Peter A. Campochiaro et al. OPHTHALMOLOGY
- SUPRACHOROIDAL DRUG INFUSION FOR THE TREATMENT OF SEVERE SUBFOVEAL HARD EXUDATES
- (2011) Stanislao Rizzo et al. RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES
- Blood-Retinal Barrier
- (2010) José Cunha-Vaz et al. EUROPEAN JOURNAL OF OPHTHALMOLOGY
- The role of blood–ocular barrier transporters in retinal drug disposition: an overview
- (2010) Masatoshi Tomi et al. Expert Opinion on Drug Metabolism & Toxicology
- A passive MEMS drug delivery pump for treatment of ocular diseases
- (2009) Ronalee Lo et al. BIOMEDICAL MICRODEVICES
- Selective Filtering of Particles by the Extracellular Matrix: An Electrostatic Bandpass
- (2009) Oliver Lieleg et al. BIOPHYSICAL JOURNAL
- An experimental platform for systemic drug delivery to the retina
- (2009) M. Campbell et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Adult vitreous structure and postnatal changes
- (2008) M M Le Goff et al. EYE
- Role of Ocular Melanin in Ophthalmic Physiology and Pathology
- (2008) Dan-Ning Hu et al. PHOTOCHEMISTRY AND PHOTOBIOLOGY
- Effect of Focused Ultrasound Applied With an Ultrasound Contrast Agent on the Tight Junctional Integrity of the Brain Microvascular Endothelium
- (2008) Nickolai Sheikov et al. ULTRASOUND IN MEDICINE AND BIOLOGY
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started