Zinc Binding Inhibits Cellular Uptake and Antifungal Activity of Histatin-5 in Candida albicans

Histatin 5 Metallopeptides and Their Potential against Candida albicans Pathogenicity and Drug Resistance

(2021) Gabriela Vieira Silva Zolin et al.   Biomolecules

A Novel Role for Histatin 5 in Combination with Zinc to Promote Commensalism in C. albicans Survivor Cells

(2021) Hannah L. Norris et al.   Pathogens

Zinc Binding by Histatin 5 Promotes Fungicidal Membrane Disruption in C. albicans and C. glabrata

(2020) Hannah L. Norris et al.   Journal of Fungi

Low levels of salivary metals, oral microbiome composition and dental decay

(2020) Elyse Davis et al.   Scientific Reports

Dynamical Oligomerisation of Histidine Rich Intrinsically Disordered Proteins Is Regulated through Zinc-Histidine Interactions

(2019) Carolina Cragnell et al.   Biomolecules

Specific metallo-protein interactions and antimicrobial activity in Histatin-5, an intrinsically disordered salivary peptide

(2019) Tyler G. McCaslin et al.   Scientific Reports

Salivary metals, age, and gender correlate with cultivable oral Candida carriage levels

(2018) Hannah L. Norris et al.   Journal of Oral Microbiology

Zinc in Infection and Inflammation

(2017) et al.   Nutrients

Calcium ions tune the zinc-sequestering properties and antimicrobial activity of human S100A12

(2016) Lisa S. Cunden et al.   Chemical Science

Chemical–Biological Properties of Zinc Sensors TSQ and Zinquin: Formation of Sensor-Zn-Protein Adducts versus Zn(Sensor)2 Complexes

(2015) Andrew B. Nowakowski et al.   INORGANIC CHEMISTRY

Nutritional Immunity: S100 Proteins at the Host-Pathogen Interface

(2015) Joseph P. Zackular et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

How Does It Kill?: Understanding the Candidacidal Mechanism of Salivary Histatin 5

(2014) Sumant Puri et al.   EUKARYOTIC CELL

Iron Binding Modulates Candidacidal Properties of Salivary Histatin 5

(2014) S. Puri et al.   JOURNAL OF DENTAL RESEARCH

Efficient Synthesis and In Vivo Incorporation of Acridon-2-ylalanine, a Fluorescent Amino Acid for Lifetime and Förster Resonance Energy Transfer/Luminescence Resonance Energy Transfer Studies

(2013) Lee C. Speight et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Reactions of the Fluorescent Sensor, Zinquin, with the Zinc-Proteome: Adduct Formation and Ligand Substitution

(2011) Andrew B. Nowakowski et al.   INORGANIC CHEMISTRY

Histatin 5 Uptake byCandida albicansUtilizes Polyamine Transporters Dur3 and Dur31 Proteins

(2011) Rohitashw Kumar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Growth of Candida albicans hyphae

(2011) Peter E. Sudbery   NATURE REVIEWS MICROBIOLOGY

Structural Characterization and Antimicrobial Activity of the Zn(II) Complex with P113 (Demegen), a Derivative of Histatin 5

(2010) Elena Porciatti et al.   INORGANIC CHEMISTRY

Salivary histatin 5 internalization by translocation, but not endocytosis, is required for fungicidal activity in Candida albicans

(2010) Woong Sik Jang et al.   MOLECULAR MICROBIOLOGY

Concentration and fate of histatins and acidic proline-rich proteins in the oral environment

(2009) Melanie Campese et al.   ARCHIVES OF ORAL BIOLOGY

Both Ca2+ and Zn2+ are essential for S100A12 protein oligomerization and function

(2009) Olga V Moroz et al.   BMC BIOCHEMISTRY

Uptake of the antifungal cationic peptide Histatin 5 byCandida albicansSsa2p requires binding to non-conventional sites within the ATPase domain

(2008) Jianing N. Sun et al.   MOLECULAR MICROBIOLOGY

The Antimicrobial Peptide Histatin-5 Causes a Spatially Restricted Disruption on the Candida albicans Surface, Allowing Rapid Entry of the Peptide into the Cytoplasm

(2008) A. Brian Mochon et al.   PLoS Pathogens