ERBB4 is over-expressed in human colon cancer and enhances cellular transformation

The ErbB4 Ligand Neuregulin-4 Protects against Experimental Necrotizing Enterocolitis

(2014) Steven J. McElroy et al.   AMERICAN JOURNAL OF PATHOLOGY

Localization of phosphorylated ErbB1-4 and heregulin in colorectal cancer

(2014) Keigo Mitsui et al.   BMC CANCER

Hypoxia-Driven Gene Expression Is an Independent Prognostic Factor in Stage II and III Colon Cancer Patients

(2014) J. Dekervel et al.   CLINICAL CANCER RESEARCH

Hypoxia-inducible Factor-1α Induces ErbB4 Signaling in the Differentiating Mammary Gland

(2014) Ilkka Paatero et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hypoxia-Inducible Factors Modulate the Stemness and Malignancy of Colon Cancer Cells by Playing Opposite Roles in Canonical Wnt Signaling

(2014) Paula Santoyo-Ramos et al.   PLoS One

The ErbB4 CYT2 variant protects EGFR from ligand-induced degradation to enhance cancer cell motility

(2014) T. Kiuchi et al.   Science Signaling

LGR5 positivity defines stem-like cells in colorectal cancer

(2013) Daniela Hirsch et al.   CARCINOGENESIS

Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal

(2013) J. Gao et al.   Science Signaling

Villin Expression Is Frequently Lost in Poorly Differentiated Colon Cancer

(2012) Diego Arango et al.   AMERICAN JOURNAL OF PATHOLOGY

Neuregulin-4 Is a Survival Factor for Colon Epithelial Cells both in Culture andin Vivo

(2012) Jessica K. Bernard et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lineage Tracing Reveals Lgr5+ Stem Cell Activity in Mouse Intestinal Adenomas

(2012) A. G. Schepers et al.   SCIENCE

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.

(2012) Ethan Cerami et al.   Cancer Discovery

Claudin-1 Up-regulates the Repressor ZEB-1 to Inhibit E-Cadherin Expression in Colon Cancer Cells

(2011) Amar B. Singh et al.   GASTROENTEROLOGY

Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium

(2011) Toshiro Sato et al.   GASTROENTEROLOGY

BVES regulates EMT in human corneal and colon cancer cells and is silenced via promoter methylation in human colorectal carcinoma

(2011) Christopher S. Williams et al.   JOURNAL OF CLINICAL INVESTIGATION

The intestinal stem cell markers Bmi1 and Lgr5 identify two functionally distinct populations

(2011) K. S. Yan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ErbB4 promotes cyclooxygenase-2 expression and cell survival in colon epithelial cells

(2010) Mark R Frey et al.   LABORATORY INVESTIGATION

Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts

(2010) Toshiro Sato et al.   NATURE

Experimentally Derived Metastasis Gene Expression Profile Predicts Recurrence and Death in Patients With Colon Cancer

(2009) J. Joshua Smith et al.   GASTROENTEROLOGY

Tumor-specific apoptosis caused by deletion of the ERBB3 pseudo-kinase in mouse intestinal epithelium

(2009) Daekee Lee et al.   JOURNAL OF CLINICAL INVESTIGATION

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

(2009) Toshiro Sato et al.   NATURE

Suppression of breast cancer cell growth by a monoclonal antibody targeting cleavable ErbB4 isoforms

(2009) M Hollmén et al.   ONCOGENE

Clinical utility of type 1 growth factor receptor expression in colon cancer

(2008) Sher-Ping Leung et al.   AMERICAN JOURNAL OF SURGERY

System-wide Investigation of ErbB4 Reveals 19 Sites of Tyr Phosphorylation that Are Unusually Selective in Their Recruitment Properties

(2008) Alexis Kaushansky et al.   CHEMISTRY & BIOLOGY

The ErbB4 Growth Factor Receptor Is Required for Colon Epithelial Cell Survival in the Presence of TNF

(2008) Mark R. Frey et al.   GASTROENTEROLOGY

ErbB receptors, their ligands, and the consequences of their activation and inhibition in the myocardium

(2008) Stephen J. Fuller et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Crypt stem cells as the cells-of-origin of intestinal cancer

(2008) Nick Barker et al.   NATURE

Isoform-specific monoubiquitination, endocytosis, and degradation of alternatively spliced ErbB4 isoforms

(2008) M. Sundvall et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA