Article
Endocrinology & Metabolism
U. Cucinotta, A. Gambadauro, F. Galletta, L. Cannavo, C. Cuppari, G. Ceravolo, C. Damiano, C. Paino, S. Sestito, I Rulli, E. Gitto
Summary: Although infection rates in neonatal intensive care units have decreased, neonatal sepsis remains a major cause of morbidity and mortality in newborns worldwide. The lack of a universally accepted definition and the variability in clinical presentation make diagnosis of neonatal sepsis challenging. This paper provides an updated overview of the etiology, clinical presentation, diagnosis, and treatment of neonatal sepsis.
JOURNAL OF BIOLOGICAL REGULATORS AND HOMEOSTATIC AGENTS
(2022)
Article
Endocrinology & Metabolism
Zhengxia Mao, Ruilin Wu, Huan Yu, Yujiao Zhang, Wenbin Dong, Lile Zou, Xiaoping Lei
Summary: Offspring of pregnant women with gestational diabetes mellitus (GDM) are at risk for glucometabolic disorders. This study found that maternal fructosamine levels before delivery were associated with neonatal glucometabolic disorders, but the association with large for gestational age (LGA) infants was weaker.
JOURNAL OF DIABETES RESEARCH
(2022)
Article
Pediatrics
Azima Kureshi, Rubia Khalak, Jamie Gifford, Upender Munshi
Summary: This study aimed to evaluate early neonatal morbidities associated with maternal obesity. The study found that infants born to obese mothers are more likely to have transient tachypnea of newborn, respiratory distress syndrome, and hypoglycemia, and they are also more likely to be delivered by cesarean section.
FRONTIERS IN PEDIATRICS
(2022)
Article
Pediatrics
Saygin Abali, Serdar Beken, Eda Albayrak, Aysegul Inamlik, Burcu Bulum, Ezgi Bulbul, Gulten Zeynep Eksi, Zeynep Alize Ay, Melis Karabay, Didem Kaya, Muge Halici, Serap Semiz, Ayse Korkmaz
Summary: This study aimed to compare early postnatal problems and growth of small-for-gestational-age infants with different definitions of SGA. The study found that infants with a birth weight below -2 SDS were more likely to experience severe hypoglycemia and polycythemia compared to infants with birth weight between -1.28 SDS and -2 SDS or those with optimal-for-gestational-age birth weight.
FRONTIERS IN PEDIATRICS
(2021)
Article
Computer Science, Information Systems
Yasmina Souley Dosso, Daniel Kyrollos, Kimberley J. Greenwood, Joann Harrold, James R. Green
Summary: The development of non-contact patient monitoring applications for the neonatal intensive care unit (NICU) is an active research area, particularly in facial video analysis. This paper evaluates the state-of-the-art in face detection in the NICU setting and demonstrates how fine-tuning can increase neonatal face detector robustness.
Article
Obstetrics & Gynecology
Adharsh Ponnapakkam, Donald Rees, Maria Cristina Gallup, Kaashif A. Ahmad, Dena Miller, Angela Fagiana, Nicholas R. Carr
Summary: The study found that a supplementation-based hypoglycemia guideline including donor milk can effectively reduce NICU admission rates for asymptomatic hypoglycemia and help mothers achieve breastfeeding goals.
JOURNAL OF PERINATOLOGY
(2021)
Review
Endocrinology & Metabolism
Laura Costanza De Angelis, Giorgia Brigati, Giulia Polleri, Mariya Malova, Alessandro Parodi, Diego Minghetti, Andrea Rossi, Paolo Massirio, Cristina Traggiai, Mohamad Maghnie, Luca Antonio Ramenghi
Summary: Neonatal hypoglycemia is common and usually resolves within the first 48 to 72 hours of life. Severe and prolonged hypoglycemia is associated with cerebral damage, potentially leading to neuronal injury.
FRONTIERS IN ENDOCRINOLOGY
(2021)
Article
Multidisciplinary Sciences
Polly Soo Xi Yap, Chun Wie Chong, Azanna Ahmad Kamar, Ivan Kok Seng Yap, Yao Mun Choo, Nai Ming Lai, Cindy Shuan Ju Teh
Summary: There are significant differences in the gut microbiota composition and metabolites between preterm and term infants, with factors like gestational age and birth weight exerting a sustained impact on the dynamics of gut microbial composition and metabolism up to one year of age. Early intervention may provide metabolic rescue to preterm infants from abnormal gut microbial colonization and succession.
SCIENTIFIC REPORTS
(2021)
Article
Endocrinology & Metabolism
Meng-qin Wang, Ying Zhuang, Ya-ning Zheng
Summary: Neonatal hypoglycemia is a common symptom that can occur due to inadequate transfer of nutrients through the placental barrier. The use of terbutaline is associated with a high risk of neonatal hypoglycemia, emphasizing the importance of timely detection and intervention.
DIABETES METABOLIC SYNDROME AND OBESITY
(2023)
Article
Pediatrics
Sharmeen Azher, Joaquim M. B. Pinheiro, Brendan Philbin, Jamie Gifford, Rubia Khalak
Summary: Maternal obesity is associated with increased risk factors and prolonged hospital stay, leading to higher costs in the full-term nursery for infants born to obese mothers.
FRONTIERS IN PEDIATRICS
(2022)
Review
Pediatrics
J. M. Alsweiler, N. Heather, D. L. Harris, C. J. D. McKinlay
Summary: Severe and prolonged neonatal hypoglycemia can cause brain injury, while the long-term consequences of mild or transitional hypoglycemia are uncertain. Currently, there is no diagnostic test to determine if an infant has neuroglycopenia, which makes the blood glucose monitoring screening for neonatal hypoglycemia not meeting the screening test principles. However, screening and treating at-risk infants with hypoglycemia appears to preserve cognitive function compared to those without episodes.
FRONTIERS IN PEDIATRICS
(2022)
Article
Veterinary Sciences
Merve Ider, Amir Naseri, Mahmut Ok, Alper Erturk, Murat Kaan Durgut, Suleyman Serhat Iyigun
Summary: This study aimed to investigate the development of brain damage in hypoglycemic calves with neonatal diarrhea and the diagnostic and prognostic significance of these biomarkers. The study found that the concentrations of brain injury biomarkers were higher in hypoglycemic calves with diarrhea compared to healthy calves, while variables of severe hypoglycemia, severe acidosis, and sepsis were not predictive of prognosis.
FRONTIERS IN VETERINARY SCIENCE
(2023)
Article
Chemistry, Analytical
Ning Zhang, Olivia Wood, Zhiyin Yang, Jianfei Xie
Summary: In any healthcare setting, it is important to monitor and control airflow and ventilation with a thermostat. Computational fluid dynamics (CFD) simulations are used to study the airflow and heat transfer inside a neonatal intensive care unit (NICU) in this study. Realistic dimensions and thermophysical characteristics of the climate are considered in the modeling. The results show sensible flow structures and heat transfer, and the artificial intelligence (AI) model further improves the thermal performance predictions by using machine learning (ML) and considering important geometric and thermophysical parameters.
Article
Endocrinology & Metabolism
Delia Bogdanet, Miguel Angel Luque-Fernandez, Michelle Toth-Castillo, Gernot Desoye, Paula M. O'Shea, Fidelma P. Dunne, Jose A. Halperin
Summary: There is an association between early pregnancy maternal levels of plasma glycated CD59 (pGCD59) and neonatal hypoglycemia (NH).
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Article
Pediatrics
Sarbattama Sen, Sara Cherkerzian, Daria Turner, Carmen Monthe-Dreze, Elisa Abdulhayoglu, John A. F. Zupancic
Summary: A graded approach to IV dextrose treatment for neonatal hypoglycemia was associated with decreased blood glucose lability, reduced length of stay in the neonatal intensive care unit, and lower cost of care for infants.
JOURNAL OF PEDIATRICS
(2021)