Genetic determinants of polygenic prediction accuracy within a population

Polygenic risk score as a possible tool for identifying familial monogenic causes of complex diseases

(2022) Tianyuan Lu et al.   GENETICS IN MEDICINE

Estimation of non-additive genetic variance in human complex traits from a large sample of unrelated individuals

(2021) Valentin Hivert et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A polygenic risk score to predict future adult short stature amongst children

(2021) Tianyuan Lu et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Block coordinate descent algorithm improves variable selection and estimation in error‐in‐variables regression

(2021) Célia Escribe et al.   GENETIC EPIDEMIOLOGY

Predictive Accuracy of a Polygenic Risk Score–Enhanced Prediction Model vs a Clinical Risk Score for Coronary Artery Disease

(2020) Joshua Elliott et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Variable prediction accuracy of polygenic scores within an ancestry group

(2020) Hakhamanesh Mostafavi et al.   eLife

Quantification of the overall contribution of gene-environment interaction for obesity-related traits

(2020) Jonathan Sulc et al.   Nature Communications

Inferring Gene-by-Environment Interactions with a Bayesian Whole-Genome Regression Model

(2020) Matthew Kerin et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Polygenic Prediction of Weight and Obesity Trajectories from Birth to Adulthood

(2019) Amit V. Khera et al.   CELL

Towards clinical utility of polygenic risk scores

(2019) Samuel A Lambert et al.   HUMAN MOLECULAR GENETICS

Genotype-by-environment interactions inferred from genetic effects on phenotypic variability in the UK Biobank

(2019) Huanwei Wang et al.   Science Advances

Non-additive Effects in Genomic Selection

(2018) Luis Varona et al.   Frontiers in Genetics

Meta-analysis of genome-wide association studies for height and body mass index in ∼700000 individuals of European ancestry

(2018) Loic Yengo et al.   HUMAN MOLECULAR GENETICS

Genomic Risk Prediction of Coronary Artery Disease in 480,000 Adults

(2018) Michael Inouye et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Colocalization of GWAS and eQTL Signals Detects Target Genes

(2016) Farhad Hormozdiari et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A reference panel of 64,976 haplotypes for genotype imputation

(2016)   NATURE GENETICS

Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets

(2016) Zhihong Zhu et al.   NATURE GENETICS

Dominance Genetic Variation Contributes Little to the Missing Heritability for Human Complex Traits

(2015) Zhihong Zhu et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology

(2015) Sue Richards et al.   GENETICS IN MEDICINE

A global reference for human genetic variation

(2015) Richard A. Gibbs et al.   NATURE

A comprehensive 1000 Genomes–based genome-wide association meta-analysis of coronary artery disease

(2015) Majid Nikpay et al.   NATURE GENETICS

An atlas of genetic correlations across human diseases and traits

(2015) Brendan Bulik-Sullivan et al.   NATURE GENETICS

LD Score regression distinguishes confounding from polygenicity in genome-wide association studies

(2015) Brendan K Bulik-Sullivan et al.   NATURE GENETICS

Efficient Bayesian mixed-model analysis increases association power in large cohorts

(2015) Po-Ru Loh et al.   NATURE GENETICS

ACMG clinical laboratory standards for next-generation sequencing

(2013) Heidi L. Rehm et al.   GENETICS IN MEDICINE

Inclusion of Gene-Gene and Gene-Environment Interactions Unlikely to Dramatically Improve Risk Prediction for Complex Diseases

(2012) Hugues Aschard et al.   AMERICAN JOURNAL OF HUMAN GENETICS

CHRNA3genotype, nicotine dependence, lung function and disease in the general population

(2012) Diljit Kaur-Knudsen et al.   EUROPEAN RESPIRATORY JOURNAL

FTO genotype is associated with phenotypic variability of body mass index

(2012) Jian Yang et al.   NATURE

An integrated map of genetic variation from 1,092 human genomes

(2012)   NATURE

Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits

(2012) Jian Yang et al.   NATURE GENETICS

GCTA: A Tool for Genome-wide Complex Trait Analysis

(2010) Jian Yang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

On the Use of Variance per Genotype as a Tool to Identify Quantitative Trait Interaction Effects: A Report from the Women's Genome Health Study

(2010) Guillaume Paré et al.   PLoS Genetics

Nicotinic Receptor Gene Variants Influence Susceptibility to Heavy Smoking

(2008) V. L. Stevens et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Data and Theory Point to Mainly Additive Genetic Variance for Complex Traits

(2008) William G. Hill et al.   PLoS Genetics