Article
Computer Science, Interdisciplinary Applications
Matteo Moro, Vito Paolo Pastore, Chaira Tacchino, Paola Durand, Isabella Blanchi, Paolo Moretti, Francesca Odone, Maura Casadio
Summary: This paper proposes a computer-aided pipeline for assessing infants' motion patterns from 2D video recordings, aiming to provide an early detection tool for neurological disorders.
COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE
(2022)
Article
Multidisciplinary Sciences
Hirokazu Doi, Akira Furui, Rena Ueda, Koji Shimatani, Midori Yamamoto, Kenichi Sakurai, Chisato Mori, Toshio Tsuji
Summary: This study explored the association between spontaneous body movement patterns in neonates and the risk of autism spectrum disorders (ASD). The findings suggest that ASD risk may be detected earlier than previously thought, as indicated by the pattern of movement in the neonatal stage.
SCIENTIFIC REPORTS
(2023)
Article
Pediatrics
Aysu Kahraman, Halil Alkan, Hasan Tolga Celik, Akmer Mutlu
Summary: The study revealed that infants with hyperbilirubinemia had poorer motor repertoire compared to a control group, and fidgety movement scores decreased as bilirubin value increased.
EUROPEAN JOURNAL OF PEDIATRICS
(2022)
Article
Multidisciplinary Sciences
Ryutaro Jo, Kazuma Yama, Yuto Aita, Kota Tsutsumi, Chikako Ishihara, Masato Maruyama, Kaori Takeda, Eiji Nishinaga, Ken-ichiro Shibasaki, Seiji Morishima
Summary: The diversity of oral microbiome in 18-month-old infants was significantly lower than that in parents, and the composition of microbiome differed significantly between infants and parents. Additionally, the microbiome of infants was more similar to that of their mothers, indicating that parents' oral microbiome influences that of children under 18 months of age.
SCIENTIFIC REPORTS
(2021)
Article
Medicine, General & Internal
Daniel Groos, Lars Adde, Sindre Aubert, Lynn Boswell, Raye-Ann de Regnier, Toril Fjortoft, Deborah Gaebler-Spira, Andreas Haukeland, Marianne Loennecken, Michael Msall, Unn Inger Moinichen, Aurelie Pascal, Colleen Peyton, Heri Ramampiaro, Michael D. Schreiber, Inger Elisabeth Silberg, Nils Thomas Songstad, Niranjan Thomas, Christine Van den Broeck, Gunn Kristin Oberg, Espen A. F. Ihlen, Ragnhild Stoen
Summary: In this prognostic study, a deep learning-based method was developed to predict cerebral palsy (CP) based on videos of infants' spontaneous movements at 9 to 18 weeks' corrected age. The method showed promising accuracy in external validation, suggesting its potential for objective early detection of CP in clinical settings using deep learning-based software.
Article
Pediatrics
Qi Zhou, Edmond Kelly, Thuy Mai Luu, Xiang Y. Ye, Joseph Ting, Prakesh S. S. Shah, Shoo K. K. Lee
Summary: This study examined the incidence, mortality, short-term morbidity, and long-term neurodevelopmental outcomes of invasive fungal infection (IFI) among preterm infants in Canada. The study found that the incidence of IFI was 1.3%, and infants with IFI had higher mortality and adverse neurodevelopmental outcomes compared to those with non-fungal infections and no infections.
FRONTIERS IN PEDIATRICS
(2023)
Article
Multidisciplinary Sciences
Yuta Shinya, Masahiko Kawai, Fusako Niwa, Yasuhiro Kanakogi, Masahiro Imafuku, Masako Myowa
Summary: There is growing evidence that preterm children are at an increased risk of poor executive functioning. Early cognitive flexibility is a possible predictor of later executive function. This study found that preterm infants showed atypical patterns of oculomotor response shifting, and lower inhibition was associated with poorer cognitive development and attentional shifting.
SCIENTIFIC REPORTS
(2022)
Article
Neurosciences
I. Y. Dolinskaya, I. A. Solopova, D. S. Zhvansky, E. S. Keshishian, Y. Ivanenko
Summary: The study found that as age increases, there is an increase in correlation between upper and lower limb muscle activity, reflecting a gradual emergence of elements of coordinative neuromuscular behavior. Additionally, correlations between arm and leg muscle responses also increased during passive leg movements. These findings suggest maturation of physiologically relevant neuromuscular network connections during the transition from spontaneous-like to voluntary goal-directed movements in early development.
NEUROSCIENCE LETTERS
(2021)
Article
Pediatrics
Ylva Fredriksson Kaul, Kerstin Rosander, Claes von Hofsten, Katarina Strand Brodd, Gerd Holmstrom, Lena Hellstrom-Westas
Summary: The ability to attend to and smoothly track a moving object in infancy is an early marker of cognition and attention at 6.5 years. Measures of eye-head tracking of moving objects in early infancy are associated with long-term cognitive and attention outcomes. These findings suggest that early coordination of eye and head movements in gaze tracking may be a useful target for future intervention studies to improve cognitive and attention outcomes in preterm infants.
PEDIATRIC RESEARCH
(2022)
Article
Pediatrics
Mary Anne Ryan, Deirdre M. Murray, Eugene M. Dempsey, Sean R. Mathieson, Vicki Livingstone, Geraldine B. Boylan
Summary: This study aimed to describe the neurodevelopmental outcomes of healthy low-risk moderate to late preterm infants at 18 months of age and compare them to term-born infants. The results showed that moderate to late preterm infants scored significantly lower in eye-hand coordination, personal, social and emotional development, gross motor development, general developmental, and foundations of learning. This suggests that they are at risk of suboptimal neurodevelopmental outcomes.
FRONTIERS IN PEDIATRICS
(2023)
Article
Pediatrics
Thiviya Selvanathan, Pearl Zaki, Mia A. McLean, Stephanie H. Au-Young, Cecil M. Y. Chau, Vann Chau, Anne R. Synnes, Linh G. Ly, Edmond Kelly, Ruth E. Grunau, Steven P. Miller
Summary: We assessed variability of analgesic use across three tertiary neonatal intensive care units accounting for early-life pain, and determined whether analgesia exposure modifies associations between early-life pain and neurodevelopment.
PEDIATRIC RESEARCH
(2023)
Article
Pediatrics
Jun Wang, Xiushu Shen, Hong Yang, Wei Shi, Xiaoyun Zhu, Herong Gao, Huanhuan Yin, Fanzhe Meng, Yun Wu
Summary: This study aimed to assess the reliability of motor assessment in infants with Prader-Willi syndrome, and found high levels of reliability and agreement in the assessment. Therefore, standardized quantitative assessments of motor performance can be carried out for infants with Prader-Willi syndrome.
Article
Multidisciplinary Sciences
Liz Araujo Rohr, Thais Invencao Cabral, Murilo Mageste de Moraes, Eloisa Tudella
Summary: Infants from low socioeconomic status show higher reaching duration and movement unit compared to very preterm group at six months of age. Horizontal hand orientation is moderately associated with infants at environmental risk.
Article
Food Science & Technology
Kolawole I. Ayeni, Michael Sulyok, Rudolf Krska, Benedikt Warth, Chibundu N. Ezekiel
Summary: This study evaluated the presence of mycotoxins and other contaminants in complementary foods consumed by Nigerian infants and young children. The results showed that some foods exceeded the EU safety threshold for aflatoxin and fumonisin. Other mycotoxins were also detected. The study emphasizes the importance of storage and hygiene practices during food preparation and feeding.
Article
Multidisciplinary Sciences
Alma Gharib, Barbara L. Thompson
Summary: Development of attention systems is crucial for cognitive and social behavior maturation. This study utilizes eye-tracking technology to record and assess visual behavior in 2.5-month old infants, providing normative data for their fixation and saccade behavior at this age. The findings demonstrate the feasibility of using eye-tracking in infants and highlight the importance of tailored modifications for obtaining high-quality data.
Article
Multidisciplinary Sciences
Satoshi Miyamoto, Zu Soh, Shigeyuki Okahara, Akira Furui, Taiichi Takasaki, Keijiro Katayama, Shinya Takahashi, Toshio Tsuji
Summary: This study explored the relationship between the number of microbubbles in cardiopulmonary bypass surgery and four circulation factors, and proposed a neural-networked model for estimation. Experimental data showed the significance of these factors in predicting the number of microbubbles.
SCIENTIFIC REPORTS
(2021)
Article
Engineering, Biomedical
Akira Furui, Ryota Onishi, Akihito Takeuchi, Tomoyuki Akiyama, Toshio Tsuji
Summary: This article proposed a stochastic EEG model based on multivariate scale mixture distribution to represent non-Gaussian characteristics associated with epileptic seizures. Experimental results demonstrated the validity and applicability of the model in epileptic seizure detection with high accuracy.
IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING
(2021)
Article
Psychology, Biological
Hirokazu Doi, Kazuki Yamaguchi, Shoma Sugisaki
Summary: The study found that participants were more likely to perceive violin sound when presented with an unconscious image of a violin, rather than a piano, supporting the influence of visual information on musical timbre perception.
QUARTERLY JOURNAL OF EXPERIMENTAL PSYCHOLOGY
(2022)
Article
Peripheral Vascular Disease
Tomohisa Nezu, Naohisa Hosomi, Kazumasa Yoshimura, Daisuke Kuzume, Hiroyuki Naito, Shiro Aoki, Yuko Morimoto, Masato Kinboshi, Takeshi Yoshida, Yuji Shiga, Naoto Kinoshita, Akira Furui, Genta Tabuchi, Hiroki Ueno, Toshio Tsuji, Hirofumi Maruyama
Summary: This study aimed to predict the functional outcome of patients with acute ischemic stroke using multivariate linear discriminant analysis and neural network analysis. The results showed that nutritional status and serum alkaline phosphatase (ALP) levels were independently associated with poor stroke outcomes.
JOURNAL OF ATHEROSCLEROSIS AND THROMBOSIS
(2022)
Article
Clinical Neurology
Koji Shimonaga, Seiji Hama, Akira Furui, Akiko Yanagawa, Akihiko Kandori, Hirokazu Atsumori, Shigeto Yamawaki, Toshinori Matsushige, Toshio Tsuji
Summary: This study examined the impact of cerebrovascular reactivity (CVR) changes on cognitive function after extracranial-intracranial bypass (EC-IC bypass). The results showed that EC-IC bypass primarily improved CVR in the surgical hemisphere. After the surgery, an increase in CVR was associated with improved accuracy on cognitive tasks, but the speed of completion varied between the left and right surgical sides. This suggests the existence of a trade-off mechanism between speed and accuracy, which operates differently in the left and right cerebral hemispheres.
NEUROSURGICAL REVIEW
(2022)
Article
Robotics
Takumi Nagasawa, Kenta Masui, Hirokazu Doi, Keiko Ogawa-Ochiai, Norimichi Tsumura
Summary: This paper introduces an approach for estimating the emotions of video viewers from remote measurements, and analyzes the relationship between brain wave features and physiological signals to improve the accuracy of continuous emotion estimation.
ARTIFICIAL LIFE AND ROBOTICS
(2022)
Article
Behavioral Sciences
Hirokazu Doi, Chieko Kanai, Haruhisa Ohta
Summary: An increasing number of studies have shown that there are similarities and shared causes between ASD and ADHD. However, comparing these two conditions is complicated by the sex differences within each condition. This study aimed to compare the cognitive functioning between ASD and ADHD, while considering sex differences. The findings revealed that both diagnosis and sex are critical factors in determining the cognitive profiles of people with ASD and ADHD.
Article
Engineering, Electrical & Electronic
Ziqiang Xu, Toshiki Sakagawa, Akira Furui, Shumma Jomyo, Masanori Morita, Masamichi Ando, Toshio Tsuji
Summary: This paper proposes a method for robust estimation of respiratory rate (RR) using a biodegradable piezoelectric sensor and analyzes the robustness differences of different biomarkers under pain stimulation. The results show that the arterial pulse wave near the elbow has the best robustness and can be used to estimate RR.
IEEE SENSORS JOURNAL
(2022)
Article
Engineering, Biomedical
Ziqiang Xu, Toshiki Sakagawa, Akira Furui, Shumma Jomyo, Masanori Morita, Masamichi Ando, Toshio Tsuji
Summary: This study reports a method to estimate rapid changes in peripheral arterial stiffness induced by sympathetic nervous system activity (SNSA) using local pulse wave velocity (LPWV), and further quantifies SNSA based on the estimated stiffness. The validity of LPWV in the quantitative evaluation of SNSA is demonstrated, and blood pressure correction can be optional depending on application scenarios.
IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING
(2022)
Proceedings Paper
Computer Science, Artificial Intelligence
Yuki Hashimoto, Akira Furui, Koji Shimatani, Maura Casadio, Paolo Moretti, Pietro Morasso, Toshio Tsuji
Summary: The assessment of general movements (GMs) in infants is a useful tool for early diagnosis of neurodevelopmental disorders. However, it currently relies on visual inspection by experts, prompting the need for an automated solution. This study proposes an automated GMs classification method that removes unnecessary background information and adjusts the infant's body position using preprocessing networks, followed by a motion classification network based on a two-stream structure. Experimental results demonstrate that the proposed method outperforms baseline models and existing methods.
MEDICAL IMAGE COMPUTING AND COMPUTER ASSISTED INTERVENTION, MICCAI 2022, PT II
(2022)
Proceedings Paper
Automation & Control Systems
Akira Furui, Kosuke Nakagaki, Toshio Tsuji
Summary: Myoelectric prosthetic hands are designed to replace lost arm function in amputees. This study proposes a biomimetic control method that integrates an impedance model with an A-type muscle model, demonstrating better correlation with actual human joint angles compared to traditional methods. The experimental results show that the proposed method can achieve natural prosthetic hand movement similar to that of a human, allowing for voluntary hand movements.
2021 IEEE INTERNATIONAL CONFERENCE ON ROBOTICS AND AUTOMATION (ICRA 2021)
(2021)
Proceedings Paper
Engineering, Biomedical
Hiroto Sakai, Akira Furui, Seiji Hama, Akiko Yanagawa, Koki Kubo, Yutaro Morisako, Yuki Orino, Maho Hamai, Kasumi Fujita, Tomohiko Mizuguchi, Akihiko Kandori, Toshio Tsuji
Summary: This study presents an analysis method of pen-point trajectory during the TMT based on a TBG, identifying quantitative indices representing the shape and collapse of the velocity profile. The experiment involving stroke patients revealed a correlation between the degree of collapse in the velocity profile shape and cognitive function decline.
2021 43RD ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE & BIOLOGY SOCIETY (EMBC)
(2021)
Proceedings Paper
Engineering, Biomedical
Ziqiang Xu, Akira Furui, Shumma Jomyo, Toshiki Sakagawa, Masanori Morita, Tsutomu Takai, Masamichi Ando, Toshio Tsuji
Summary: This study investigates the relationship between respiration and autonomic nervous system activity, proposing a method to extract heart rate and respiration rate simultaneously from different pulse waves. The experimental results demonstrate the detection capability under different respiratory statuses.
2021 43RD ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE & BIOLOGY SOCIETY (EMBC)
(2021)