Impacts of arsenic on Rad18 and translesion synthesis

Interactomic analysis reveals a homeostatic role for the HIV restriction factor TRIM5α in mitophagy

(2022) Bhaskar Saha et al.   Cell Reports

Arsenic co-carcinogenesis: Inhibition of DNA repair and interaction with zinc finger proteins

(2021) Xixi Zhou et al.   SEMINARS IN CANCER BIOLOGY

Endolysosomal Mesoporous Silica Nanoparticle Trafficking along Microtubular Highways

(2021) Achraf Noureddine et al.   Pharmaceutics

Molecular Mechanisms of Arsenic-Induced Disruption of DNA Repair

(2020) Lok Ming Tam et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Regulation of translesion DNA synthesis in mammalian cells

(2020) Xiaolu Ma et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Uranium and arsenic unregulated water issues on Navajo lands

(2020) Jani C. Ingram et al.   JOURNAL OF VACUUM SCIENCE & TECHNOLOGY A

PCNA Monoubiquitination Is Regulated by Diffusion of Rad6/Rad18 Complexes along RPA Filaments

(2020) Mingjie Li et al.   BIOCHEMISTRY

Differential Roles of Rad18 and Chk2 in Genome Maintenance and Skin Carcinogenesis Following UV Exposure

(2018) Yuki Tanoue et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Caught with One's Zinc Fingers in the Genome Integrity Cookie Jar

(2018) Caroline K. Vilas et al.   TRENDS IN GENETICS

Differential sensitivities of cellular XPA and PARP-1 to arsenite inhibition and zinc rescue

(2017) Xiaofeng Ding et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Low dose arsenite confers resistance to UV induced apoptosis via p53-MDM2 pathway in ketatinocytes

(2017) Y Zhou et al.   Oncogenesis

Rad18 confers hematopoietic progenitor cell DNA damage tolerance independently of the Fanconi Anemia pathwayin vivo

(2016) Yang Yang et al.   NUCLEIC ACIDS RESEARCH

Translesion synthesis mechanisms depend on the nature of DNA damage in UV-irradiated human cells

(2016) Annabel Quinet et al.   NUCLEIC ACIDS RESEARCH

Rad18-dependent SUMOylation of human specialized DNA polymerase eta is required to prevent under-replicated DNA

(2016) Emmanuelle Despras et al.   Nature Communications

Bayesian Deconvolution of Mass and Ion Mobility Spectra: From Binary Interactions to Polydisperse Ensembles

(2015) Michael T. Marty et al.   ANALYTICAL CHEMISTRY

Regulation of Rad6/Rad18 Activity During DNA Damage Tolerance

(2015) Mark Hedglin et al.   Annual Review of Biophysics

RAD18 Is a Maternal Limiting Factor Silencing the UV-Dependent DNA Damage Checkpoint in Xenopus Embryos

(2015) Chames Kermi et al.   DEVELOPMENTAL CELL

DNA lesion identity drives choice of damage tolerance pathway in murine cell chromosomes

(2015) Isadora S. Cohen et al.   NUCLEIC ACIDS RESEARCH

RAD18 Activates the G2/M Checkpoint through DNA Damage Signaling to Maintain Genome Integrity after Ionizing Radiation Exposure

(2015) Megumi Sasatani et al.   PLoS One

Genotoxic and epigenetic mechanisms in arsenic carcinogenicity

(2014) Elisa Bustaffa et al.   ARCHIVES OF TOXICOLOGY

NMR Structure of the Human Rad18 Zinc Finger in Complex with Ubiquitin Defines a Class of UBZ Domains in Proteins Linked to the DNA Damage Response

(2014) Alessandro A. Rizzo et al.   BIOCHEMISTRY

DNA damage-specific deubiquitination regulates Rad18 functions to suppress mutagenesis

(2014) Michelle K. Zeman et al.   JOURNAL OF CELL BIOLOGY

Molecular features in arsenic-induced lung tumors

(2013) Roland Hubaux et al.   Molecular Cancer

BRCA1 promotes the ubiquitination of PCNA and recruitment of translesion polymerases in response to replication blockade

(2013) F. Tian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reduction of arsenite-enhanced ultraviolet radiation-induced DNA damage by supplemental zinc

(2013) Karen L. Cooper et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Poly(ADP-Ribose) Polymerase-1 Inhibition by Arsenite Promotes the Survival of Cells With Unrepaired DNA Lesions Induced by UV Exposure

(2012) Xu-Jun Qin et al.   TOXICOLOGICAL SCIENCES

The E3 ubiquitin ligase RAD18 regulates ubiquitylation and chromatin loading of FANCD2 and FANCI

(2011) S. A. Williams et al.   BLOOD

Analysis of protein dynamics at active, stalled, and collapsed replication forks

(2011) B. M. Sirbu et al.   GENES & DEVELOPMENT

Arsenite Interacts Selectively with Zinc Finger Proteins Containing C3H1 or C4 Motifs

(2011) Xixi Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Meiotic functions of RAD18

(2011) A. Inagaki et al.   JOURNAL OF CELL SCIENCE

Symmetry and Asymmetry of the RING–RING Dimer of Rad18

(2011) Anding Huang et al.   JOURNAL OF MOLECULAR BIOLOGY

γH2Ax: Biomarker of Damage or Functional Participant in DNA Repair “All that Glitters Is not Gold!”

(2011) James E. Cleaver   PHOTOCHEMISTRY AND PHOTOBIOLOGY

Human RAD18 Interacts with Ubiquitylated Chromatin Components and Facilitates RAD9 Recruitment to DNA Double Strand Breaks

(2011) Akiko Inagaki et al.   PLoS One

Arsenic transformation predisposes human skin keratinocytes to UV-induced DNA damage yet enhances their survival apparently by diminishing oxidant response

(2011) Yang Sun et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Rad18-mediated Translesion Synthesis of Bulky DNA Adducts Is Coupled to Activation of the Fanconi Anemia DNA Repair Pathway

(2010) Ihn Young Song et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

UV-Induced Association of the CSB Remodeling Protein with Chromatin Requires ATP-Dependent Relief of N-Terminal Autorepression

(2010) Robert J. Lake et al.   MOLECULAR CELL

RAD18 transmits DNA damage signalling to elicit homologous recombination repair

(2009) Jun Huang et al.   NATURE CELL BIOLOGY

Dynamic localization of human RAD18 during the cell cycle and a functional connection with DNA double-strand break repair

(2008) Akiko Inagaki et al.   DNA REPAIR

PARP inhibition versus PARP-1 silencing: different outcomes in terms of single-strand break repair and radiation susceptibility

(2008) C. Godon et al.   NUCLEIC ACIDS RESEARCH