Article
Spectroscopy
Dayu Hu, Xiaosong Xu, Zeyin Zhao, Changqi Li, Ye Tian, Qiang Liu, Bo Shao, Shuo Chen, Yue Zhao, Ling Li, Huan Bi, Ang Chen, Cheng Fu, Xiaoyu Cui, Yu Zeng
Summary: The study utilized SERS technology to detect metabolites in urine, reflecting the cancer status. Combining results from urine supernatant and sediment, SERS showed high diagnostic sensitivity and specificity for BCa.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2021)
Article
Biochemistry & Molecular Biology
Eric Boateng Osei, Liliia Paniushkina, Konrad Wilhelm, Juergen Popp, Irina Nazarenko, Christoph Krafft
Summary: Extracellular vesicles (EVs) ranging in size from 60 to 800 nm were isolated from plasma of control and prostate cancer patients using differential centrifugation and ultrafiltration techniques. Spontaneous Raman and surface-enhanced Raman spectroscopy (SERS) were employed to identify fractions that best discriminate between control and cancer patients, with results showing that EV12 and EV120 fractions provide the most effective separation.
Article
Multidisciplinary Sciences
Zhongli Huang, Shijian Feng, Qiunong Guan, Tao Lin, Jianhua Zhao, Christopher Y. C. Nguan, Haishan Zeng, David Harriman, Hong Li, Caigan Du
Summary: This study aimed to develop a non-invasive tool for monitoring kidney transplant function using SERS. Results showed significant correlations between urine SERS spectra and conventional chemical markers of kidney transplant function, indicating a strong predictive ability of this method. The urine SERS spectral analysis could be used as a convenient method for rapid assessment of kidney transplant function.
SCIENTIFIC REPORTS
(2021)
Review
Health Care Sciences & Services
Charlotte Delrue, Marijn M. Speeckaert
Summary: Raman spectroscopy is a spectroscopic technique that can detect biochemical changes in biological samples at the molecular level, making it a valuable tool for disease diagnosis and prognosis. It offers several advantages over conventional methods.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Chemistry, Analytical
Zedong Zhang, Dekun Wang, Chang Liu, Jianguo Dong, Mengmeng Jiang, Xue Mi, Xiaoyue Tan, Yuying Zhang
Summary: Surface-enhanced Raman spectroscopy (SERS) is a powerful technique that uses metallic nanostructures to amplify weak Raman signals. However, detecting subtle molecular changes in fixed cells/tissues using SERS is challenging due to size limitations of the metal nanoparticles. In this study, a penetration-then-growth strategy was proposed to detect molecular changes in the fibrogenic process using SERS.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Review
Biotechnology & Applied Microbiology
Ting Lin, Ya-Li Song, Pu Kuang, Si Chen, Zhigang Mao, Ting-Ting Zeng
Summary: The optical technology of Surface-enhanced Raman scattering (SERS) plays a significant role in cancer diagnosis, with its performance being highly dependent on the properties and morphology of the substrate. SERS technology offers advantages of rapidity, high specificity, and high sensitivity.
Article
Chemistry, Multidisciplinary
Shu Hu, Jingyu Wang, Yue-Jiao Zhang, Bao-Ying Wen, Si-Si Wu, Petar M. Radjenovic, Zhilin Yang, Bin Ren, Jian-Feng Li
Summary: In this study, the shell and structural effect of shell-isolated nanoparticle-enhanced Raman spectroscopy (SHINERS) were investigated. It was found that the field enhancement loss due to the shell could be overcome by optimizing the coupling geometry of the shell-isolated nanoparticles (SHINs), and signal enhancement could be further optimized by altering the aggregation geometries of the nanoparticles.
Article
Chemistry, Multidisciplinary
Gary Sean Cooney, David Talaga, Vicky Ury-Thiery, Yann Fichou, Yuhan Huang, Sophie Lecomte, Sebastien Bonhommeau
Summary: In this study, TERS was used to visualize the spatial distribution of adenine, protein secondary structure, and amino acids in single polyadenosine-induced tau fibrils. The findings provide insights into the incorporation of the polyadenosine cofactor in the fibril structure and its interaction with amino acids. TERS proves to be a powerful technique for studying cofactors in individual tau fibrils and their mode of interaction.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Review
Engineering, Environmental
Lifang Xie, Kedong Gong, Yangyang Liu, Liwu Zhang
Summary: Nanoplastics, at sizes smaller than 1000 nm, are found ubiquitously in various environmental media and pose a potential health risk due to their ability to easily enter cells. In this review, we summarize the prevalent analytical techniques for identifying nanoplastics, with a focus on the advantages and disadvantages of surface-enhanced Raman spectroscopy (SERS). We discuss the principles of SERS, advances in nanoplastic detection using SERS, and the application of SERS in real environmental samples. Furthermore, we highlight the importance of efficient SERS substrates and pretreatment methodologies to enable practical nanoplastic detection and identify future research needs in this field.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2023)
Article
Biophysics
Lei Wu, Armando Dias, Lorena Dieguez
Summary: Cancer is the second leading cause of death worldwide, making early diagnosis and personalized treatment crucial. Surface enhanced Raman spectroscopy (SERS) has emerged as an effective biosensing technique in cancer theranostics, allowing ultra-sensitive and multiplex detection of tumor nucleic acids. It has great potential for clinical cancer detection and subtyping.
BIOSENSORS & BIOELECTRONICS
(2022)
Article
Engineering, Biomedical
Qiong Wu, Qin Ding, Wanzun Lin, Youliang Weng, Shangyuan Feng, Rong Chen, Chuanben Chen, Sufang Qiu, Duo Lin
Summary: This study combined surface-enhanced Raman spectroscopy with proteomics to analyze exosomes secreted from radioresistant nasopharyngeal cancer cells. Specific protein expression variations associated with radioresistance formation were identified, including collagen alpha-2 (I) chain (COL1A2), which is associated with a favorable prognosis in NPC. A deep learning model-based diagnostic model was developed to accurately identify exosomes from the radioresistant group. This research demonstrates the potential of exosomes as a biomarker for predicting radioresistance and provides a rapid and sensitive liquid biopsy method for personalized clinical NPC treatment.
ADVANCED HEALTHCARE MATERIALS
(2022)
Article
Materials Science, Multidisciplinary
Limei Liu, Pablo Martinez Pancorbo, Ting-Hui Xiao, Saya Noguchi, Machiko Marumi, Hiroki Segawa, Siddhant Karhadkar, Julia Gala de Pablo, Kotaro Hiramatsu, Yasutaka Kitahama, Tamitake Itoh, Junle Qu, Kuniharu Takei, Keisuke Goda
Summary: Over the past two decades, wearable sensor technology has experienced significant growth. One recent breakthrough is the development of wearable chemical sensors based on surface-enhanced Raman spectroscopy (SERS), which can universally and noninvasively detect molecular fingerprints. However, these sensors are not scalable due to their complex fabrication process and limited multifunctional sensing capabilities. A highly scalable, wearable SERS sensor based on a low-cost, ultrathin, flexible, stretchable, adhesive, and biointegratable gold nanomesh is demonstrated in this study. It can be worn on any surface and used for label-free, large-scale, in situ sensing of diverse analytes. To showcase its practical utility, the sensor is tested for the detection of sweat biomarkers, drugs of abuse, and microplastics. This wearable SERS sensor represents a significant step towards the generalizability and practicality of wearable sensing technology.
ADVANCED OPTICAL MATERIALS
(2022)
Review
Biotechnology & Applied Microbiology
Anindita Das, Hsieh-Chih Tsai, Tapas Sen, Rakesh S. Moirangthem
Summary: Optical imaging modalities play a critical role in cancer research, providing molecular and cellular information with minimal invasiveness. Photothermal therapy (PTT) has shown great potential due to its high specificity and noninvasiveness. The combination of surface-enhanced Raman spectroscopy (SERS)-based optical imaging with PTT has shown tremendous potential in cancer theranostics.
Article
Chemistry, Physical
Yumin Zhang, Ruoyu Chen, Fugang Liu, Peng Miao, Li Lin, Jian Ye
Summary: The detection of deep-seated lesions is challenging due to the strong photon absorption and scattering of biological tissues. In this work, the combination of ultra-bright SERS nanotags and TRS is used to achieve non-invasive and photosafe detection of phantom lesions hidden in biological tissues. The results demonstrate the potential of transmission Raman-guided identification and non-invasive imaging for clinically safe cancer diagnoses.
Article
Chemistry, Multidisciplinary
Yu Wen, Vinh X. Truong, Ming Li
Summary: The study introduced a three-in-one theranostic nanoprobe for image-guided surgical resection of tumors and intraoperative surface-enhanced Raman spectroscopy (SERS) guided thermosurgical elimination of residual microtumors. In vivo experiments demonstrated complete eradication of microtumors without local recurrence and 100% tumor-free survivability, offering a robust platform for real-time intraoperative eradication of residual microtumors with significant improvement of surgical outcomes.
Article
Spectroscopy
Shuzhen Tang, Siqi Gao, Jianshu Xu, Mengmeng Zheng, Yimei Huang, Yun Yu, Juqiang Lin
Summary: In this study, silver nanoparticles-based surface-enhanced Raman spectroscopy combined with a serum protein purification method was used to screen liver tumors. The method showed high diagnostic sensitivity and specificity for liver cancer, indicating great potential for detection and screening of this disease.
SPECTROSCOPY LETTERS
(2021)
Correction
Biochemical Research Methods
Qiong Wu, Sufang Qiu, Yun Yu, Weiwei Chen, Huijing Lin, Duo Lin, Shangyuan Feng, Rong Chen
Summary: This study assesses the radiotherapy effect for nasopharyngeal cancer using plasma surface-enhanced Raman spectroscopy technology, with corrections provided by the Optical Society of America in accordance with the OSA Open Access Publishing Agreement.
BIOMEDICAL OPTICS EXPRESS
(2021)
Article
Spectroscopy
Yamin Lin, Siqi Gao, Mengmeng Zheng, Shuzhen Tang, Kecan Lin, Shusen Xie, Yun Yu, Juqiang Lin
Summary: A novel extraction and isolation analysis method utilizing hydroxyapatite particles (HAp) for detecting breast cancer by targeting adsorption of serum albumin showed promising potential with an ideal diagnostic accuracy of 98.6%. The method not only preserved the structure and property of albumin, but also demonstrated non-invasive and sensitive capabilities for breast cancer screening.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2021)
Article
Spectroscopy
Siqi Gao, Yamin Lin, Xin Zhao, Jiamin Gao, Shusen Xie, Wei Gong, Yun Yu, Juqiang Lin
Summary: Surface-enhanced Raman spectroscopy (SERS) is an ultrasensitive, non-invasive, and rapid detection technology for cancer diagnosis. In this study, a novel blood serum analysis strategy using coffee ring effect-assisted label-free SERS was developed for cancer screening. By combining PLS-SVM algorithm with serum SERS detection, an ideal diagnostic accuracy of 100% could be achieved for differentiating cancers from the normal group.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Spectroscopy
Yamin Lin, Jiamin Gao, Shuzhen Tang, Xin Zhao, Mengmeng Zheng, Wei Gong, Shusen Xie, Siqi Gao, Yun Yu, Juqiang Lin
Summary: A new serum protein analysis method combined with SERS technology was used for breast cancer detection. The diagnostic model established through multivariate statistical analysis showed promising performance in classifying breast cancer, providing a potential new approach for diagnosis.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2021)
Article
Spectroscopy
Mengmeng Zheng, Yamin Lin, Jianshu Xu, Jiamin Gao, Wei Gong, Shusen Xie, Yun Yu, Juqiang Lin
Summary: This study compared electroporation-assisted and ultrasound-assisted delivery methods for surface-enhanced Raman scattering (SERS) detection, finding that the two methods have different capabilities in delivering nanoparticles into living cells. Ultrasound-assisted SERS showed better sensitivity, specificity, and accuracy in discriminating and identifying drug-treated degranulated mast cells compared to electroporation-assisted SERS.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Chemistry, Analytical
Yamin Lin, Juqiang Lin, Mengmeng Zheng, Wei Gong, Huan Li, Zhengyu Shu, Weiwei Du, Siqi Gao, Yun Yu
Summary: In this study, a novel extraction-isolation albumin analysis method for prostate cancer screening was developed by utilizing the specific adsorption capacity of hydroxyapatite (HAp) combined with surface-enhanced Raman spectroscopy (SERS). The results showed that the HAp flower particles exhibited superior adsorption-release capacity for albumin and could be used for the diagnosis of prostate cancer through SERS spectral analysis. The PLS-SVM model achieved a high diagnostic accuracy of 95.00% for differentiating normal volunteers from prostate patient groups.
ANALYTICA CHIMICA ACTA
(2022)
Article
Spectroscopy
Xin Zhao, Qingjiang Xu, Yamin Lin, Weiwei Du, Xin Bai, Jiamin Gao, Tao Li, Yimei Huang, Yun Yu, Xiang Wu, Juqiang Lin
Summary: This study aimed to screen for prostate cancer and benign prostatic hyperplasia in human plasma using SERS and multivariate statistical algorithms. It found that PLS-SVM algorithm outperformed PCA-LDA algorithm in the pre-diagnosis and screening of PCa.
JOURNAL OF RAMAN SPECTROSCOPY
(2022)
Article
Chemistry, Analytical
Weiwei Chen, Xiaobo Li, Shangwen Xu, Qin Chen, Zhongping Zhang, Decai Yuan, Guoqiang Wei, Hao Huang, Xihai Li, Yun Yu
Summary: The study investigated the efficacy rule of the Huo-Xue-Hua-Yu decoction on fracture healing in rats using surface-enhanced Raman scattering technology. Results showed that the combination of ingredients in HXHYD had a stronger effect, with CHA playing a key role in fracture repair.
ANALYTICAL METHODS
(2022)
Proceedings Paper
Biochemical Research Methods
Xin Zhao, Tingting Lin, Jiamin Gao, Yamin Lin, Wei Gong, Xiang Wu, Qingjiang Xu, Tao Li, Yun Yu, Juqiang Lin
Summary: Prostate cancer is a leading cause of cancer-related death in men aged 50 and above, with PSA being a widely used tumor marker for early diagnosis. However, high levels of PSA can lead to false-positive results and misdiagnoses. BPH presents with similar symptoms as PCa but can be treated with proper treatment. Metabolomics technology using urine analysis shows promise in non-invasive cancer detection and diagnosis. SERS combined with PCA-LDA analysis of urine samples has shown good potential in distinguishing between PCa and BPH with high sensitivity and specificity.
OPTICS IN HEALTH CARE AND BIOMEDICAL OPTICS XI
(2021)
Proceedings Paper
Biochemical Research Methods
Dan Liu, Jiamin Gao, Yamin Lin, Wei Gong, Xiang Wu, QingJiang Xu, Tao Li, Yun Yu, Juqiang Lin
Summary: The study demonstrates that the combination of SERS technology and PCA-LDA algorithm has great potential in the development of label-free, non-invasive and accurate detection and screening of kidney stones.
OPTICS IN HEALTH CARE AND BIOMEDICAL OPTICS XI
(2021)
Article
Chemistry, Analytical
Yamin Lin, Mengmeng Zheng, Xin Zhao, Dan Liu, Jiamin Gao, Wei Gong, Shusen Xie, Siqi Gao, Yun Yu, Juqiang Lin
Summary: This research introduced a simple one-pot sol-thermal strategy to prepare a highly sensitive and stable SERS substrate, enabling the detection of rhodamine 6G and crystal violet. Additionally, the substrate could be utilized for quantitative analysis of crystal violet in wastewater.
ANALYTICAL METHODS
(2021)
Article
Chemistry, Analytical
Siqi Gao, Yamin Lin, Mengmeng Zheng, Yating Lin, Kecan Lin, Shusen Xie, Yun Yu, Juqiang Lin
Summary: This study introduced a label-free albumin targeted analysis method utilizing HAp and SERS for liver cancer screening at different stages. By using a high concentration of PO43- solution as the release agent, it overcame the limitations of traditional methods and achieved high diagnostic accuracies through SERS spectra analysis.
ANALYTICAL METHODS
(2021)
Article
Chemistry, Analytical
Weiwei Chen, Shangwen Xu, Xiaoyang Wang, Guoqiang Wei, Quanxing Hong, Hao Huang, Yun Yu
Summary: This study aimed to evaluate the feasibility of using intracellularly-grown-Au-nanoparticle (IGAuNP)-based surface-enhanced Raman scattering (SERS) technology to classify two types of nasopharyngeal cancer cell lines (CNE2 and CNE1). The IGAuNP technology effectively enhances Raman signals of cells, providing a high signal-to-noise ratio and more characteristic Raman peaks for differentiating biochemical components. Linear discriminant analysis (LDA) and support vector machine (SVM) analysis of SERS spectral data achieved a diagnostic sensitivity, specificity, and accuracy of 100% for distinguishing between CNE2 and CNE1 cells, suggesting great potential for identifying nasopharyngeal carcinoma cell lines.
ANALYTICAL METHODS
(2021)
Article
Spectroscopy
Zh. E. Ozbekova, A. A. Abdyldaev, A. A. Kulmyrzaev
Summary: This study compared two drying methods for cow and yak muscles, finding that freeze drying caused less discoloration. Additionally, analysis of fluorescence spectra allowed for accurate prediction of chemical composition and color characteristics of the muscles.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Leo Mandic, Ivan Ljubic, Iva Dzeba
Summary: In this study, a combined experimental and computational approach was used to investigate the photoexcitation and photodegradation mechanisms of Doxazosin (DOX). The results provide valuable insights into the primary events following the photoexcitation of DOX and its potential applications.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Xiufeng Wang, Yao Jin, Wenhui Ai, Siqi Wang, Zhiqing Zhang, Ting Zhou, Fang Wang, Guodong Zhang
Summary: This study successfully synthesized near infrared fluorescence Ag2S quantum dots (QDs) and developed a dual-mode sensor for sulfide anion using the excellent oxidase-like characteristics of manganese dioxide (MnO2) nanosheets. The sensor showed a wider detection range, higher sensitivity, and shorter reaction time, making it suitable for highly selective detection of sulfide in different concentration ranges.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Yafei Li, Yanming Ma, Chuantao Zheng, Di Yu, Lien Hu, Shuo Yang, Fang Song, Yadan Li, Shuanghai Liu, Zhanrui Zhang, Yu Zhang, Yiding Wang, Frank K. Tittel
Summary: To effectively monitor gas explosion and coal spontaneous combustion in coal mine, an intrinsically safe and explosion-proof dual-gas sensor system was developed for methane (CH4) and carbon monoxide (CO) measurement. The system achieved different measurement ranges using laser scanning and gas cells, and improved stability and accuracy through gas pre-treatment and temperature compensation algorithm.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Pei-Rong Chen, Li-Kang Chu
Summary: In this study, the hydrates of glyoxal were investigated using infrared absorption spectrometry. The results showed that at low concentrations, glyoxal mainly exists as monomeric dihydrate. These findings provide suitable detection windows for further research on the roles of glyoxal and its hydrates in atmospheric and aerosol chemistry, as well as the relevant reaction kinetics.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Nichole O'Neill, Thamires A. Lima, Fabio Furlan Ferreira, Nicolas J. Alvarez, Reinhard Schweitzer-Stenner
Summary: This study determines the main fibril axis of GHG gel-forming fibrils using various techniques and compares the results with simulated data. The analysis suggests that the hydrophobic xz-surfaces of GHG fibrils could be a good target for the adsorption of hydrophobic drugs.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Mengyuan Liu, Hanchuang Zhu, Yikun Fang, Caiyun Liu, Xinke Li, Xiaohui Zhang, Lixue Ma, Kun Wang, Miaohui Yu, Wenlong Sheng, Baocun Zhu
Summary: ABHS is an efficient fluorescent probe that can accurately and sensitively detect Al3+ with strong resistance to interference. It also demonstrates excellent detection and imaging capabilities in complex real samples.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Ahmed S. El-Shafie, Evana Rahman, Yasser Gadelhak, Rehab Mahmoud, Marwa El-Azary
Summary: The recycling of waste mandarin peels into biochar (MRBC) has been used as a high performance and cost-effective adsorbent for treating polluted wastewater effluents. Batch adsorption studies were conducted to analyze the adsorption competency of MRBC on two dyes, methylene blue (MB) and basic fuchsin (BF), either in individual solutions or binary combinations. The results showed that MRBC was capable of effectively removing a high percentage of both dyes. However, the adsorption capacity decreased when the dyes were combined. The cost estimation of MRBC production and wastewater treatment indicated that both were relatively low.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Anindita Bhatta, Jahnabi Upadhyaya, Dipak Chamlagai, Lincoln Dkhar, Pynskhemborlang T. Phanrang, Mohan Rao Kollipara, Sivaprasad Mitra
Summary: Derivatives of thiazole-pyrazole fused benzo-coumarin compounds were synthesized and their photophysical properties were investigated. The synthesized coumarin compounds showed potential as therapeutic agents for Alzheimer's disease, inhibiting acetylcholinesterase activity. The presence of human serum albumin was found to affect the inhibition activity.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Yongwei Duan, Quancheng Liu, Yiju Zhu, Qi Zhang, Xiaohui Duan, Hu Deng, Liping Shang
Summary: In this study, the phase transition of CL-20 was observed using terahertz spectroscopy, and quantum chemical calculations were employed to analyze the vibrations. The results indicated changes in the vibrations of CL-20 before and after phase transition.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Yuefeng Gao, Sai Xu, Baojiu Chen
Summary: This study synthesized Cs2NaInCl6 nanocrystals co-doped with Sb3+ and Tb3+ ions as probes for copper ions detection in lubricating oil. The introduction of Sb3+ effectively reduced the band gap of the host material and enabled energy transfer pathway for Tb3+ emission. The doped Tb3+ ions resulted in the suppression of emission due to electron transfer. The Cs2NaInCl6: 2.5 %Sb3+, 40 %Tb3+ NCs exhibited superior sensitivity and selectivity for copper ions detection.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Yu Liu, Yue Zhang, Changyao Liu, Ce Wang, Baocai Xu, Li Zhao
Summary: A highly sensitive detection platform for heparin was developed using a cationic fluorescent dye (cresyl violet acetate) as a fluorescence probe. The platform demonstrated high selectivity towards heparin and achieved detection in both HEPES solution and serum.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Lopamudra Roy, Nivedita Pan, Susmita Mondal, Ria Ghosh, Md. Nur Hasan, Neha Bhattacharyya, Soumendra Singh, Kallol Bhattacharyya, Arpita Chattopadhyay, Samir Kumar Pal
Summary: The study focuses on the interaction between reactive oxygen species (ROS) and a spectroscopic probe called Rose Bengal (RB), encapsulated in nanoscopic sodium dodecyl sulphate (SDS) micelles and entrapped in microscopic nylon 66 solid matrix. The research demonstrates efficient interaction between ROS and RB-SDS, and investigates the mechanism of hydroxyl radicals generation. Based on these findings, a prototype device utilizing RB embedded in a nylon thin film for quantification of ROS in extracellular fluids and food materials was developed.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Xiaosong Sun, Qihao Cui, Wenyue Dong, Qian Duan, Teng Fei
Summary: Conjugated porous polymers (CPPs) are promising sensing materials and their application in aqueous media is limited. In this study, we synthesized CPPs with porous structure and prepared nanoparticles, enabling efficient photoluminescence sensing of nitroaromatic explosives in aqueous phase.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)
Article
Spectroscopy
Maria Cristina Caggiani, Germana Barone, Paolo Mazzoleni
Summary: Raman spectroscopy is commonly used for studying glassy materials in cultural heritage, but it is more difficult to interpret the spectra and apply the technique with portable instruments. In contrast, diffuse reflectance infrared Fourier transform spectroscopy (DRIFTS) can be used in archaeometric investigations as it is portable and non-invasive. However, there is limited application of this technique to historical glasses. This exploratory work demonstrates the potential of DRIFTS, in combination with portable X-ray Fluorescence (pXRF) and EDS microanalyses, for studying the composition and alteration of glass samples in cultural heritage.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2024)