Exercise training rescues adipose tissue spexin expression and secretion in diet-induced obese mice

Effect of spexin on renal dysfunction in experimentally obese rats: potential mitigating mechanisms via galanin receptor-2

(2021) Mervat H. El-Saka et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

Spexin alleviates hypertension, hyperuricaemia, dyslipidemia and insulin resistance in high fructose diet induced metabolic syndrome in rats via enhancing PPAR-ɣ and AMPK and inhibiting IL-6 and TNF-α

(2021) Mona A. Said et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

Mouse Spexin: (II) Functional Role as a Satiety Factor inhibiting Food Intake by Regulatory Actions Within the Hypothalamus

(2021) Matthew K. H. Wong et al.   Frontiers in Endocrinology

30-Day spexin treatment of mice with diet-induced obesity (DIO) and type 2 diabetes (T2DM) increases insulin sensitivity, improves liver functions and metabolic status

(2021) Pawel A. Kolodziejski et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Spexin Promotes the Proliferation and Differentiation of C2C12 Cells In Vitro—The Effect of Exercise on SPX and SPX Receptor Expression in Skeletal Muscle In Vivo

(2021) Natalia Leciejewska et al.   Genes

Spexin as an indicator of beneficial effects of exercise in human obesity and diabetes

(2020) Abdelkrim Khadir et al.   Scientific Reports

Assessment of acute aerobic exercise in the morning versus evening on asprosin, spexin, lipocalin-2, and insulin level in overweight/obese versus normal weight adult men

(2020) Halil İbrahim Ceylan et al.   CHRONOBIOLOGY INTERNATIONAL

Cold-Inducible Klf9 Regulates Thermogenesis of Brown and Beige Fat

(2020) Heng Fan et al.   DIABETES

Short-term administration of spexin in rats reduces obesity by affecting lipolysis and lipogenesis: An in vivo and in vitro study

(2020) Ewa Pruszynska-Oszmalek et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

Palmitate differentially regulates Spexin, and its receptors Galr2 and Galr3, in GnRH neurons through mechanisms involving PKC, MAPKs, and TLR4

(2020) Lu Wang et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Spexin-Based Galanin Receptor Type 2 Agonist for Comorbid Mood Disorders and Abnormal Body Weight

(2019) Seongsik Yun et al.   Frontiers in Neuroscience

Favorable Changes in Fasting Glucose in a 6-month Self-Monitored Lifestyle Modification Programme Inversely Affects Spexin Levels in Females with Prediabetes

(2019) Nasser M. Al-Daghri et al.   Scientific Reports

Spexin protects cardiomyocytes from hypoxia-induced metabolic and mitochondrial dysfunction

(2019) Yang Liu et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Galanin peptide family regulation of glucose metabolism

(2019) Penghua Fang et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Palmitate and Nitric Oxide Regulate the Expression of Spexin and Galanin Receptors 2 and 3 in Hypothalamic Neurons

(2019) Andy Tran et al.   NEUROSCIENCE

Spexin Modulates Functions of Rat Endocrine Pancreatic Cells

(2018) Maciej Sassek et al.   PANCREAS

Spexin: A novel regulator of adipogenesis and fat tissue metabolism

(2018) Pawel A. Kolodziejski et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Decreased Spexin Levels in Patients with Type 1 and Type 2 Diabetes

(2018) Anara Karaca et al.   MEDICAL PRINCIPLES AND PRACTICE

Acute exercise regulates adipogenic gene expression in white adipose tissue

(2016) Yanyan Shen et al.   BIOLOGY OF SPORT

Decreased Circulating Levels of Spexin in Obese Children

(2016) Seema Kumar et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Regulation of Hepatocellular Fatty Acid Uptake in Mouse Models of Fatty Liver Disease with and without Functional Leptin Signaling: Roles of NfKB and SREBP-1C and the Effects of Spexin

(2016) Jasmine Ge et al.   SEMINARS IN LIVER DISEASE

The Anti-Adipogenic Potential of COUP-TFII Is Mediated by Downregulation of the Notch Target Gene Hey1

(2016) Ilse Scroyen et al.   PLoS One

Exercise Effects on White Adipose Tissue: Beiging and Metabolic Adaptations

(2015) Kristin I. Stanford et al.   DIABETES

Spexin peptide is expressed in human endocrine and epithelial tissues and reduced after glucose load in type 2 diabetes

(2015) Liping Gu et al.   PEPTIDES

Impact of exercise on muscle and nonmuscle organs

(2015) Pontus A. Boström et al.   IUBMB LIFE

Coevolution of the Spexin/Galanin/Kisspeptin Family: Spexin Activates Galanin Receptor Type II and III

(2014) Dong-Kyu Kim et al.   ENDOCRINOLOGY

Spexin is a novel human peptide that reduces adipocyte uptake of long chain fatty acids and causes weight loss in rodents with diet-induced obesity

(2014) José L. Walewski et al.   Obesity

Goldfish spexin: solution structure and novel function as a satiety factor in feeding control

(2013) Matthew K. H. Wong et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Emerging roles of zinc finger proteins in regulating adipogenesis

(2013) Shengjuan Wei et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Transcriptional Regulation of an Insulin-Sensitizing Adipokine Adipolin/CTRP12 in Adipocytes by Krüppel-Like Factor 15

(2013) Takashi Enomoto et al.   PLoS One

Regulation of glucose transport by insulin: traffic control of GLUT4

(2012) Dara Leto et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Exercise-induced galanin release facilitated GLUT4 translocation in adipocytes of type 2 diabetic rats

(2011) Yan Liang et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Increased levels of peroxisome proliferator-activated receptor gamma, coactivator 1 alpha (PGC-1α) improve lipid utilisation, insulin signalling and glucose transport in skeletal muscle of lean and insulin-resistant obese Zucker rats

(2010) C. R. Benton et al.   DIABETOLOGIA

Swimming training beneficial effects in a mice model of nonalcoholic fatty liver disease

(2010) Alini Schultz et al.   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

Modern sedentary activities promote overconsumption of food in our current obesogenic environment

(2010) J.-P. Chaput et al.   Obesity Reviews

Chicken ovalbumin upstream promoter-transcription factor II regulates nuclear receptor, myogenic, and metabolic gene expression in skeletal muscle cells

(2010) Lisa M. Crowther et al.   PHYSIOLOGICAL GENOMICS

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

(2009) Carles Cantó et al.   NATURE