Tg6F ameliorates the increase in oxidized phospholipids in the jejunum of mice fed unsaturated LysoPC or WD

Intestinal Phospholipid Remodeling Is Required for Dietary-Lipid Uptake and Survival on a High-Fat Diet

(2016) Bo Wang et al.   Cell Metabolism

Source and role of intestinally derived lysophosphatidic acid in dyslipidemia and atherosclerosis

(2015) Mohamad Navab et al.   JOURNAL OF LIPID RESEARCH

Lpcat3-dependent production of arachidonoyl phospholipids is a key determinant of triglyceride secretion

(2015) Xin Rong et al.   eLife

Group 1B phospholipase A2 inactivation suppresses atherosclerosis and metabolic diseases in LDL receptor-deficient mice

(2014) Norris I. Hollie et al.   ATHEROSCLEROSIS

Macrophages in intestinal homeostasis and inflammation

(2014) Calum C. Bain et al.   IMMUNOLOGICAL REVIEWS

Constant replenishment from circulating monocytes maintains the macrophage pool in the intestine of adult mice

(2014) Calum C Bain et al.   NATURE IMMUNOLOGY

Transintestinal Cholesterol Excretion Is an Active Metabolic Process Modulated by PCSK9 and Statin Involving ABCB1

(2013) Cédric Le May et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

A novel approach to oral apoA-I mimetic therapy

(2013) Arnab Chattopadhyay et al.   JOURNAL OF LIPID RESEARCH

Transgenic 6F tomatoes act on the small intestine to prevent systemic inflammation and dyslipidemia caused by Western diet and intestinally derived lysophosphatidic acid

(2013) Mohamad Navab et al.   JOURNAL OF LIPID RESEARCH

ApoA-I mimetics: tomatoes to the rescue

(2013) Godfrey S. Getz et al.   JOURNAL OF LIPID RESEARCH

Tomatoes, lysophosphatidic acid, and the small intestine: new pieces in the puzzle of apolipoprotein mimetic peptides?

(2013) A. T. Remaley   JOURNAL OF LIPID RESEARCH

High-Density Lipoprotein and 4F Peptide Reduce Systemic Inflammation by Modulating Intestinal Oxidized Lipid Metabolism

(2012) Mohamad Navab et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Structural, functional and molecular analysis of the effects of aging in the small intestine and colon of C57BL/6J mice

(2012) Wilma T Steegenga et al.   BMC Medical Genomics

Role of Phospholipid Oxidation Products in Atherosclerosis

(2012) Sangderk Lee et al.   CIRCULATION RESEARCH

Phospholipase A2 enzymes in metabolic and cardiovascular diseases

(2012) David Y. Hui   CURRENT OPINION IN LIPIDOLOGY

Dietary oxidizedn-3 PUFA induce oxidative stress and inflammation: role of intestinal absorption of 4-HHE and reactivity in intestinal cells

(2012) Manar Awada et al.   JOURNAL OF LIPID RESEARCH

In vivo visualization and attenuation of oxidized lipid accumulation in hypercholesterolemic zebrafish

(2011) Longhou Fang et al.   JOURNAL OF CLINICAL INVESTIGATION

D-4F-mediated reduction in metabolites of arachidonic and linoleic acids in the small intestine is associated with decreased inflammation in low-density lipoprotein receptor-null mice

(2011) Mohamad Navab et al.   JOURNAL OF LIPID RESEARCH

Intestine may be a major site of action for the apoA-I mimetic peptide 4F whether administered subcutaneously or orally

(2011) Mohamad Navab et al.   JOURNAL OF LIPID RESEARCH

Jejunum Inflammation in Obese and Diabetic Mice Impairs Enteric Glucose Detection and Modifies Nitric Oxide Release in the Hypothalamus

(2010) Thibaut Duparc et al.   ANTIOXIDANTS & REDOX SIGNALING

Aiming drug discovery at lysophosphatidic acid targets

(2010) Gabor Tigyi   BRITISH JOURNAL OF PHARMACOLOGY

Oxidized Cholesteryl Esters and Phospholipids in Zebrafish Larvae Fed a High Cholesterol Diet

(2010) Longhou Fang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Treatment of patients with cardiovascular disease with L-4F, an apo-A1 mimetic, did not improve select biomarkers of HDL function

(2010) Catherine E. Watson et al.   JOURNAL OF LIPID RESEARCH

High-Fat Diet: Bacteria Interactions Promote Intestinal Inflammation Which Precedes and Correlates with Obesity and Insulin Resistance in Mouse

(2010) Shengli Ding et al.   PLoS One

Vascular Lipid Accumulation, Lipoprotein Oxidation, and Macrophage Lipid Uptake in Hypercholesterolemic Zebrafish

(2009) Konstantin Stoletov et al.   CIRCULATION RESEARCH

The role of the small intestine in the development of dietary fat-induced obesity and insulin resistance in C57BL/6J mice

(2008) Nicole JW de Wit et al.   BMC Medical Genomics

Acyl-CoA:Lysophospholipid Acyltransferases

(2008) Hideo Shindou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Safety, pharmacokinetics, and pharmacodynamics of oral apoA-I mimetic peptide D-4F in high-risk cardiovascular patients

(2008) LeAnne T. Bloedon et al.   JOURNAL OF LIPID RESEARCH