Article
Engineering, Multidisciplinary
Shuai Xue, Lingwei Kong, Yifan Dai, Shanyong Chen, Zhifan Lin
Summary: The near-null interferometric test method for aspheric cylinders using a partial null lens and a coaxial configuration design allows for testing various aspheric cylinders with high accuracy in optical design. The proposed method provides easier test accuracy guarantee compared to existing methods, and the testability results can serve as a guide for engineers designing high-energy laser systems. The established near-null test system demonstrates simple configuration, moderate accuracy, and flexible test capacity for measurements on aspheric cylinders.
MEASUREMENT SCIENCE AND TECHNOLOGY
(2021)
Article
Optics
Xin Zhang, Haixiang Hu, Donglin Xue, Xi Yang, Wa Thang, Guanbo Qiao, Xuejun Zhang
Summary: The concept of wavefront optical spacing was proposed in this study to measure the distance between the wavefront at ideal design position and that at real surface testing position. The cat-eye CGH interferometric method proved to be effective in measuring the WOS of freeform surfaces with high metrology accuracy. Experimental results demonstrate that the method can achieve absolute accuracy, repeatability, and relative accuracy of the WOS measurement.
OPTICS AND LASERS IN ENGINEERING
(2023)
Article
Astronomy & Astrophysics
Reed Essick, Geoffrey Mo, Erik Katsavounidis
Summary: A universal null test for transient events observed with multiple sensors is derived and applied to simulated and real gravitational-wave events, to determine the significance of coincident events and identify which auxiliary channels witness real gravitational waves. Additionally, this approach can be used to study detector artifacts, quantify the statistical independence of candidate gravitational-wave signals, and determine the safety of auxiliary channels for constructing vetoes.
Article
Biotechnology & Applied Microbiology
Dan Wang, Xianhua Cai, Feng Xu, Hui Kang, Yanjin Li, Ruibing Feng
Summary: The study revealed that Ganoderic Acid A has inhibitory effects on intervertebral disc degeneration (IVDD) by suppressing H2O2-induced cell apoptosis, oxidative stress, and inflammatory responses, as well as inhibiting matrix degrading enzymes associated with IVDD. Additionally, Ganoderic Acid A also promotes the expression of extracellular matrix synthesis factors, showing protective properties against IVDD.
Article
Optics
Romita Chaudhuri, Alexander Wansha, Rosario Porras-Aguilar, Jannick P. Rolland
Summary: The implementation of an interferometric null test using a high-definition spatial light modulator (SLM) as an alternative to a computer-generated hologram is reported. The alignment process chain, including novel techniques using the SLM for alignment fiducials, is detailed. The null test of a concave freeform is successfully performed and compared with conventional interferometry, showing good agreement.
Article
Optics
Peter L. Kaulfuss, Paul M. Alsing, Edwin E. Hach, A. Matthew Smith, Michael L. Fanto
Summary: Probabilistic quantum gates play a crucial role in various aspects of linear optical quantum computing, with advancements in integrated nanophotonics making the tradeoff between resource cost and success probability more favorable. As quantum circuits generating cluster states become more complex, component analysis becomes critical. The experimental viability of testing a probabilistic gate, such as the nonlinear phase-shift gate, is demonstrated in this study, with a focus on comparing different implementation techniques and analyzing the conditions for successful operation.
Article
Optics
Yiming Liu, Jinpeng Li, Yao Hu, Shaohui Zhang, Zichen Wang, Chuheng Xu, Shuai Yang, Weiqian Zhao, Qun Hao
Summary: This paper proposes an interferometric method for radius measurement of spherical surfaces based on a small axial moving distance and the corresponding defocus wavefront. The method eliminates the dependence on a long guide rail and extends the measuring range. A defocus transform algorithm is used to eliminate the influence of the test environment and achieve fast measurement of R.
Article
Nanoscience & Nanotechnology
Zhengcong Ye, Chanfeng Wang, Lei Han, Qinrong Shen, Xiaogang Huang
Summary: This study found that Wufuyin granules (WFYG) alleviate cartilage degeneration by inhibiting pyroptosis, possibly through suppressing the activation of NLRP3 inflammasomes.
JOURNAL OF BIOMEDICAL NANOTECHNOLOGY
(2022)
Article
Pharmacology & Pharmacy
Weikang Zhang, Yuhang Gong, Xiaohang Zheng, Jianxin Qiu, Ting Jiang, Lihua Chen, Fangying Lu, Xinhui Wu, Fengmin Cheng, Zhenghua Hong
Summary: PDGF-BB promotes extracellular matrix synthesis of NPCs and inhibits pyroptosis, participating in the inhibition of IDD through regulating the MAPK signaling pathway.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Optics
Deng Ting, Liu Fengwei, Qin Die, Xu Yan, Wu Yongqian, Chen Qiang
Summary: This paper proposes a non-null interferometric measurement method for X-ray mirrors, which achieves high-precision interferometric measurement of zero ratrace error without splicing. By dividing the aspherical mirror and using a high-precision plane mirror for calibration, the ratrace error can be accurately determined and the overall aspherical mirror error can be obtained through matrix splicing. The method is validated using an example of X-ray elliptic cylindrical mirror.
ACTA OPTICA SINICA
(2022)
Article
Biochemistry & Molecular Biology
Michishige Terasaki, Keita Shibata, Yusaku Mori, Tomomi Saito, Takanori Matsui, Makoto Ohara, Tomoyasu Fukui, Keiji Hasumi, Yuichiro Higashimoto, Koji Nobe, Sho-ichi Yamagishi
Summary: SMTP-44D inhibits the formation of atherosclerotic plaques by blocking the AGEs-RAGE pathway and reduces macrophage infiltration and AGEs accumulation in the aortic roots. It also reduces foam cell formation in macrophages by suppressing the Cdk5-CD36 pathway.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Chemistry, Multidisciplinary
Can Liu, Lei Fan, Ming Guan, Qiangqiang Zheng, Jiale Jin, Xinchang Kang, Zhongyang Gao, Xiaoqian Deng, Yifan Shen, Guangyu Chu, Jingyao Chen, Zhiqiang Yu, Lei Zhou, Yue Wang
Summary: In this study, the authors found that Glutaredoxin3(GLRX3) is an important redox-regulating molecule associated with nucleus pulposus (NP) cell senescence and disc degeneration. They developed GLRX3(+) mesenchymal stem cell-derived extracellular vehicles (EVs-GLRX3) that enhanced antioxidant defense and prevented senescence cascade expansion. They also proposed a disc tissue-like biopolymer-based supramolecular hydrogel for delivering EVs-GLRX3 to treat disc degeneration. The EVs-GLRX3-loaded hydrogel attenuated mitochondrial damage, alleviated NP senescence, and restored ECM deposition.
Article
Optics
Cong Wei, Jianxin Li, Jun Ma, Mingliang Duan, Yi Zong, Xinyu Miao, Rihong Zhu, Caojin Yuan, Dangzhong Gao, Zongwei Wang
Summary: A method for full-surface defects detection on ICF capsules using a null interferometric microscope (NIM) is proposed, which achieves single-shot measurement in a single subaperture with a dynamic phase-shifting module. The eccentricity error is measured and compensated online during the scanning process. This system achieves high efficiency and resolution for full-surface defects detection on ICF capsules.
Article
Statistics & Probability
Devin Caughey, Allan Dafoe, Xinran Li, Luke Miratrix
Summary: Randomisation inference (RI) is typically interpreted as testing Fisher's 'sharp' null hypothesis that all unit-level effects are exactly zero. However, we show that many randomisation tests are also valid for a 'bounded' null hypothesis under which the unit-level effects are all non-positive (or all non-negative) but are otherwise heterogeneous. This reinterpretation and generalisation provide a broader justification for randomisation tests and a basis for exact non-parametric inference for effect quantiles.
JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES B-STATISTICAL METHODOLOGY
(2023)
Article
Medicine, Research & Experimental
Juncai He, Yan Fu, Lingling Ge, Jiaman Dai, Yajie Fang, Yijian Li, Xianliang Gu, Zui Tao, Ting Zou, Minghui Li, Yong Liu, Haiwei Xu, Zheng Qin Yin
Summary: This study investigated the activation of microglia and its contribution to photoreceptor degeneration in retinitis pigmentosa (RP). The results showed that disease-associated microglia activation can suppress the degeneration of rods and cones, reducing secondary damage caused by the accumulation of dead cells and infiltrated neutrophils.
Article
Optics
Erhui Qi, Haixiang Hu, Xiao Luo
Article
Nanoscience & Nanotechnology
Xiaoyi Liu, Jinbo Gao, Yanchao Wang, Xiaoyi Wang, Haigui Yang, Haixiang Hu, Jinsong Gao, Tarik Bourouina, Tianhong Cui
Article
Optics
Kuo Hai, Longxiang Li, Haixiang Hu, Zhiyu Zhang, Yang Bai, Xiao Luo, Liqi Yi, Xi Yang, Donglin Xue, Xuejun Zhang
Article
Optics
Guanbo Qiao, Haixiang Hu, Xuejun Zhang, Xiao Luo, Donglin Xue, Ge Zhang, Haifei Hu, Liqi Yi, Yu Yang, Weijie Deng
Summary: The study utilizes finite element and ray tracing models to assess the impact of stress-induced deformation on lightweight silicon carbide mirrors, with results aligning closely with experimental findings. Various strategies to overcome stress-induced deformation are discussed, including fabrication pre-compensation and lightweight structure redesign.
Article
Optics
Zhihua Cai, Xiaokun Wang, Haixiang Hu, Haidong Zhang, Feng Wang, Donglin Xue, Xuejun Zhang
Summary: The study introduces a modified method using single wedge compensation for measuring large convex aspheric mirrors, which can achieve high accuracy with careful alignment. Two simulation examples were designed to verify the applicability of the method, demonstrating its feasibility and flexibility.
OPTICS COMMUNICATIONS
(2021)
Article
Optics
Ling Xiong, Xiao Luo, Xuejun Zhang, Erhui Qi, Haixiang Hu, Zhenyu Liu, Feng Zhang
Summary: To improve the accuracy of testing large aspheric optics, a pose-varied test mode for the swing arm profilometer (SAP) was proposed, adjusting the pose of each scan arc to match the local best-fitting sphere for measuring off-axis aspheric surfaces with stronger asphericity. Experimental results showed a 50% increase in repeatability and a 32% increase in accuracy compared to the classical SAP mode.
Article
Optics
Cai Zhi-hua, Wang Xiao-kun, Hu Hai-xiang, Cheng Qiang, Wang Ruo-qiu, Zhang Hai-dong
Summary: This article introduces a method of using Computer Generation Hologram (CGH) to calibrate system errors in a single optical wedge test path. By analyzing the source of system error and the calibration accuracy of CGH, it is demonstrated that CGH can effectively improve the testing accuracy and reliability, addressing the issue of error coupling during the test process.
Article
Optics
Wen Chen, Ming-Jie Sun, Wei-Jie Deng, Hai-Xiang Hu, Li-Jing Li, Xue-Jun Zhang
Summary: This article introduces a hyperspectral imaging system with a simple architecture that can perform spatial imaging and spectral measuring simultaneously, as well as real-time spectral video. By using a compressive sampling strategy, efficient information retrieval and imaging can be achieved.
OPTICS AND LASERS IN ENGINEERING
(2022)
Article
Optics
Xuejun Zhang, Haixiang Hu, Xiaokun Wang, Xiao Luo, Ge Zhang, Wenxing Zhao, Xiaoyi Wang, Zhenyu Liu, Ling Xiong, Erhui Qi, Congcong Cui, Yanchao Wang, Yingjie Li, Xu Wang, Longxiang Li, Yang Bai, Qiang Cheng, Zhiyu Zhang, Ruigang Li, Wa Tang, Xuefeng Zeng, Weijie Deng, Feng Zhang
Summary: The process of manufacturing the world's largest silicon carbide (SiC) aspheric mirror involves various challenges, including the preparation of the mirror blank, asphere fabrication, testing, cladding, and coating. To overcome these difficulties, a range of innovative technologies and methods were proposed and successfully applied to produce a SiC aspheric mirror with impressive performance. The completed mirror demonstrates outstanding characteristics, such as low aerial density, high accuracy in shape testing, and low surface figure error and roughness.
LIGHT-SCIENCE & APPLICATIONS
(2022)
Article
Optics
Xin Zhang, Haixiang Hu, Donglin Xue, Xi Yang, Wa Thang, Guanbo Qiao, Xuejun Zhang
Summary: The concept of wavefront optical spacing was proposed in this study to measure the distance between the wavefront at ideal design position and that at real surface testing position. The cat-eye CGH interferometric method proved to be effective in measuring the WOS of freeform surfaces with high metrology accuracy. Experimental results demonstrate that the method can achieve absolute accuracy, repeatability, and relative accuracy of the WOS measurement.
OPTICS AND LASERS IN ENGINEERING
(2023)
Article
Optics
Xi Yang, Haixiang Hu, Donglin Xue, Xin Zhang
Summary: In this paper, a method based on minimization of Zernike gradient polynomial residual (MZGR) is proposed to estimate segment piston errors and correct erroneous phase unwrapping results. Simulations and experiments demonstrate that this method can precisely obtain the segment piston errors under complex aberration forms and varied obscurations, indicating reliable practicality.
Article
Optics
Fukun Li, Yang Bai, Haixiang Hu, Longxiang Li, Lingzhong Li, Feng Zhang, Xiao Luo, Xuejun Zhang
Summary: Fused silica glass is widely used in optical systems, and its surface quality plays a critical role in determining system performance and precision. This study establishes a roughness contact model between pitch and fused silica glass surfaces, and finds that pitch materials with a higher plasticity index can effectively improve the surface quality of the fused silica. The results of this study provide important theoretical guidance for achieving ultra-smooth polishing of large-diameter complex curved surfaces.
Proceedings Paper
Engineering, Manufacturing
Haixiang Hu, Mingzhuo Li, Xuejun Zhang, Xiao Luo, Erhui Qi, Zhenyu Liu
Summary: With the development of large-scale SiC materials and CCOS, MRF processing technology, optical manufacturing has entered the era of giant mirrors. Surface testing technology, as the basis of all optical processing, is facing challenges of high efficiency, high precision, and high accuracy. In this study, a method to estimate the actual surface error from individual measurements was proposed and validated through experiments.
SEVENTH ASIA PACIFIC CONFERENCE ON OPTICS MANUFACTURE (APCOM 2021)
(2022)
Proceedings Paper
Engineering, Electrical & Electronic
Yin Xiaolin, Tang Wa, Hu Haixiang, Zeng Xuefeng, Wang Dekang, Xue Donglin, Zhang Feng, Deng Weijie, Zhang Xuejun
FOURTH SEMINAR ON NOVEL OPTOELECTRONIC DETECTION TECHNOLOGY AND APPLICATION
(2018)
