Canagliflozin attenuates chronic unpredictable mild stress induced neuroinflammation via modulating AMPK/mTOR autophagic signaling

Dexamethasone can attenuate the pulmonary inflammatory response via regulation of the lncH19/miR-324-3p cascade

(2021) Ye Chen et al.   Journal of Inflammation-London

Dimethyl fumarate abridged tauo-/amyloidopathy in a D-Galactose/ovariectomy-induced Alzheimer's-like disease: Modulation of AMPK/SIRT-1, AKT/CREB/BDNF, AKT/GSK-3β, adiponectin/Adipo1R, and NF-κB/IL-1β/ROS trajectories

(2021) Israa M. Abd El-Fatah et al.   NEUROCHEMISTRY INTERNATIONAL

Neuroprotective Effect of SGLT2 Inhibitors

(2021) Agnieszka Pawlos et al.   MOLECULES

Fluoxetine modulates the pro-inflammatory process of IL-6, IL-1β and TNF-α levels in individuals with depression: a systematic review and meta-analysis

(2021) María Lourdes García-García et al.   PSYCHIATRY RESEARCH

Neuroinflammation and depression: A review

(2020) Romain Troubat et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Neuroprotective Effects of Fluoxetine Against Chronic Stress-Induced Neural Inflammation and Apoptosis: Involvement of the p38 Activity

(2020) Yuxiao Zhao et al.   Frontiers in Physiology

Amisulpride alleviates chronic mild stress-induced cognitive deficits: Role of prefrontal cortex microglia and Wnt/β-catenin pathway

(2020) Ahmed M. Mohamed et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Potential Therapeutic Effects of Sodium Glucose-linked Cotransporter 2 Inhibitors in Stroke

(2020) Fatima Alzahra Al Hamed et al.   CLINICAL THERAPEUTICS

Effects of Xiaoyaosan on Depressive-Like Behaviors in Rats With Chronic Unpredictable Mild Stress Through HPA Axis Induced Astrocytic Activities

(2020) Ming Song et al.   Frontiers in Psychiatry

Peripheral inflammation and blood–brain barrier disruption: effects and mechanisms

(2020) Xiaowen Huang et al.   CNS Neuroscience & Therapeutics

Stress and signaling pathways regulating autophagy: From behavioral models to psychiatric disorders

(2020) Bruna C. Pierone et al.   EXPERIMENTAL NEUROLOGY

Canagliflozin reduces inflammation and fibrosis biomarkers: a potential mechanism of action for beneficial effects of SGLT2 inhibitors in diabetic kidney disease

(2019) Hiddo J. L. Heerspink et al.   DIABETOLOGIA

Is There a Role of Autophagy in Depression and Antidepressant Action?

(2019) Nils C. Gassen et al.   Frontiers in Psychiatry

Upregulation of the nitrosylome in bipolar disorder type 1 (BP1) and major depression, but not BP2: Increased IgM antibodies to nitrosylated conjugates are associated with indicants of leaky gut

(2019) Michael Maes et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Andrographolide triggers autophagy-mediated inflammation inhibition and attenuates chronic unpredictable mild stress (CUMS)-induced depressive-like behavior in mice

(2019) Ji Geng et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Chronic Unpredictable Mild Stress in Rats Induces Colonic Inflammation

(2019) Lina Wei et al.   Frontiers in Physiology

Protective Role of Casuarinin from Melaleuca leucadendra against Ethanol-Induced Gastric Ulcer in Rats

(2019) Eman Al-Sayed et al.   PLANTA MEDICA

Mast Cells in Irritable Bowel Syndrome: A Systematic Review

(2019) Luisa Krammer et al.   Journal of Gastrointestinal and Liver Diseases

TLR4 signaling modulation of PGC1-α mediated mitochondrial biogenesis in the LPS-Chronic mild stress model: Effect of fluoxetine and pentoxiyfylline

(2019) L.H. Khedr et al.   LIFE SCIENCES

Canagliflozin exerts anti-inflammatory effects by inhibiting intracellular glucose metabolism and promoting autophagy in immune cells

(2018) Chenke Xu et al.   BIOCHEMICAL PHARMACOLOGY

IDO and TDO as a potential therapeutic target in different types of depression

(2018) Yanjie Qin et al.   METABOLIC BRAIN DISEASE

Validation of sodium/glucose cotransporter proteins in human brain as a potential marker for temporal narrowing of the trauma formation

(2018) Sabrina Oerter et al.   INTERNATIONAL JOURNAL OF LEGAL MEDICINE

The Role of Indoleamine 2,3-Dioxygenase in a Mouse Model of Neuroinflammation-Induced Depression

(2018) Nikoletta Dobos et al.   JOURNAL OF ALZHEIMERS DISEASE

Leaky gut biomarkers in depression and suicidal behavior

(2018) L. Ohlsson et al.   ACTA PSYCHIATRICA SCANDINAVICA

Protective effect of Convolvulus pluricaulis against neuroinflammation associated depressive behavior induced by chronic unpredictable mild stress in rat

(2018) Girdhari Lal Gupta et al.   BIOMEDICINE & PHARMACOTHERAPY

Recognizing the Leaky Gut as a Trans-diagnostic Target for Neuroimmune Disorders Using Clinical Chemistry and Molecular Immunology Assays

(2018) Denitsa Simeonova et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Canagliflozin and Stroke in Type 2 Diabetes Mellitus

(2018) Zien Zhou et al.   STROKE

Medial Habenula-Interpeduncular Nucleus Circuit Contributes to Anhedonia-Like Behavior in a Rat Model of Depression

(2018) Chunpeng Xu et al.   Frontiers in Behavioral Neuroscience

Antidepressant effect of helicid in chronic unpredictable mild stress model in rats

(2018) Jiucui Tong et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Baicalin ameliorates chronic unpredictable mild stress-induced depressive behavior: Involving the inhibition of NLRP3 inflammasome activation in rat prefrontal cortex

(2017) Xiaoxin Liu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Anti-inflammatory treatment for major depressive disorder: implications for patients with an elevated immune profile and non-responders to standard antidepressant therapy

(2017) Paula Kopschina Feltes et al.   JOURNAL OF PSYCHOPHARMACOLOGY

The Gut-Brain Axis, BDNF, NMDA and CNS Disorders

(2016) Raeesah Maqsood et al.   NEUROCHEMICAL RESEARCH

Chronic unpredictable mild stress generates oxidative stress and systemic inflammation in rats

(2016) Ana Laura López-López et al.   PHYSIOLOGY & BEHAVIOR

FKBP5/FKBP51 enhances autophagy to synergize with antidepressant action

(2015) Nils C Gassen et al.   Autophagy

Antidepressant-like effect of geniposide on chronic unpredictable mild stress-induced depressive rats by regulating the hypothalamus–pituitary–adrenal axis

(2015) Li Cai et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Molecular network of neuronal autophagy in the pathophysiology and treatment of depression

(2015) Jack Jia et al.   Neuroscience Bulletin

Invokana (Canagliflozin) as a Dual Inhibitor of Acetylcholinesterase and Sodium Glucose Co-Transporter 2: Advancement in Alzheimer’s Disease- Diabetes Type 2 Linkage via an Enzoinformatics Study

(2014) Syed Rizvi et al.   CNS & Neurological Disorders-Drug Targets

The role of mTOR in depression and antidepressant responses

(2014) Helena M. Abelaira et al.   LIFE SCIENCES

Pretreatment Brain States Identify Likely Nonresponse to Standard Treatments for Depression

(2013) Callie L. McGrath et al.   BIOLOGICAL PSYCHIATRY

Coenzyme Q10 displays antidepressant-like activity with reduction of hippocampal oxidative/nitrosative DNA damage in chronically stressed rats

(2013) Sawsan Aboul-Fotouh   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

The Role of Autophagy in Parkinson's Disease

(2013) M. A. Lynch-Day et al.   Cold Spring Harbor Perspectives in Medicine

Regional distribution of SGLT activity in rat brain in vivo

(2012) Amy S. Yu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Increased IgA and IgM responses against gut commensals in chronic depression: Further evidence for increased bacterial translocation or leaky gut

(2012) Michael Maes et al.   JOURNAL OF AFFECTIVE DISORDERS

Antidepressant Drugs Diversely Affect Autophagy Pathways in Astrocytes and Neurons—Dissociation from Cholesterol Homeostasis

(2011) Jürgen Zschocke et al.   NEUROPSYCHOPHARMACOLOGY

Sodium–glucose transport: role in diabetes mellitus and potential clinical implications

(2010) Volker Vallon et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

The antidepressants maprotiline and fluoxetine induce Type II autophagic cell death in drug-resistant Burkitt's lymphoma

(2010) Suzanne M. Cloonan et al.   INTERNATIONAL JOURNAL OF CANCER

Context and strain-dependent behavioral response to stress

(2008) Katarzyna Nosek et al.   Behavioral and Brain Functions

Antidepressive-like effects of rapamycin in animal models: Implications for mTOR inhibition as a new target for treatment of affective disorders

(2008) C. Cleary et al.   BRAIN RESEARCH BULLETIN