Do cytotoxicity and cell death cause false positive results in the in vitro comet assay?

Collection and storage of human white blood cells for analysis of DNA damage and repair activity using the comet assay in molecular epidemiology studies

(2021) Peter Møller et al.   MUTAGENESIS

Validation of the in vitro comet assay for DNA cross-links and altered bases detection

(2021) Damián Muruzabal et al.   ARCHIVES OF TOXICOLOGY

Validation of the 3D reconstructed human skin Comet assay, an animal-free alternative for following-up positive results from standard in vitro genotoxicity assays

(2020) Stefan Pfuhler et al.   MUTAGENESIS

Potassium bromate as positive assay control for the Fpg-modified comet assay

(2020) Peter Møller et al.   MUTAGENESIS

Improving Quality in Nanoparticle-Induced Cytotoxicity Testing by a Tiered Inter-Laboratory Comparison Study

(2020) Inge Nelissen et al.   Nanomaterials

Minimum Information for Reporting on the Comet Assay (MIRCA): recommendations for describing comet assay procedures and results

(2020) Peter Møller et al.   Nature Protocols

Genotoxicity of Nanomaterials: Advanced In Vitro Models and High Throughput Methods for Human Hazard Assessment—A Review

(2020) Yvonne Kohl et al.   Nanomaterials

The enzyme-modified comet assay: Past, present and future

(2020) Damián Muruzabal et al.   FOOD AND CHEMICAL TOXICOLOGY

An optimized comet-based in vitro DNA repair assay to assess base and nucleotide excision repair activity

(2020) Sona Vodenkova et al.   Nature Protocols

Technical recommendations to perform the alkaline standard and enzyme-modified comet assay in human biomonitoring studies

(2019) Amaya Azqueta et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Application of the comet assay in human biomonitoring: An hCOMET perspective

(2019) Amaya Azqueta et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

The comet assay: ready for 30 more years

(2018) Peter Møller   MUTAGENESIS

Sensitive detection of DNA oxidation damage induced by nanomaterials

(2017) Andrew Collins et al.   FREE RADICAL BIOLOGY AND MEDICINE

Pan-European inter-laboratory studies on a panel of in vitro cytotoxicity and pro-inflammation assays for nanoparticles

(2016) Jean-Pascal Piret et al.   ARCHIVES OF TOXICOLOGY

A Multilaboratory Toxicological Assessment of a Panel of 10 Engineered Nanomaterials to Human Health—ENPRA Project—The Highlights, Limitations, and Current and Future Challenges

(2016) Ali Kermanizadeh et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS

In vitrogenotoxicity testing of four reference metal nanomaterials, titanium dioxide, zinc oxide, cerium oxide and silver: towards reliable hazard assessment

(2016) Naouale El Yamani et al.   MUTAGENESIS

Impact of nanosilver on various DNA lesions and HPRT gene mutations – effects of charge and surface coating

(2015) Anna Huk et al.   Particle and Fibre Toxicology

The use of the comet assay for the evaluation of the genotoxicity of nanomaterials

(2015) Amaya Azqueta et al.   Frontiers in Genetics

Measurement of oxidative damage to DNA in nanomaterial exposed cells and animals

(2014) Peter Møller et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Variation of DNA damage levels in peripheral blood mononuclear cells isolated in different laboratories

(2014) R. W. L. Godschalk et al.   MUTAGENESIS

The low molecular weight DNA diffusion assay as an indicator of cytotoxicity for the in vitro comet assay

(2014) G. Speit et al.   MUTAGENESIS

Applications of the comet assay in particle toxicology: air pollution and engineered nanomaterials exposure

(2014) P. Moller et al.   MUTAGENESIS

Is the toxic potential of nanosilver dependent on its size?

(2014) Anna Huk et al.   Particle and Fibre Toxicology

The essential comet assay: a comprehensive guide to measuring DNA damage and repair

(2013) Amaya Azqueta et al.   ARCHIVES OF TOXICOLOGY

Interlaboratory Evaluation of in Vitro Cytotoxicity and Inflammatory Responses to Engineered Nanomaterials: The NIEHS Nano GO Consortium

(2013) Tian Xia et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

A combination of in vitro comet assay and micronucleus test using human lymphoblastoid TK6 cells

(2013) A. Kimura et al.   MUTAGENESIS

The comet assay, DNA damage, DNA repair and cytotoxicity: hedgehogs are not always dead

(2013) Y. Lorenzo et al.   MUTAGENESIS

An ECVAG inter-laboratory validation study of the comet assay: inter-laboratory and intra-laboratory variations of DNA strand breaks and FPG-sensitive sites in human mononuclear cells

(2013) C. Ersson et al.   MUTAGENESIS

Mechanisms of genotoxicity. A review ofin vitroandin vivostudies with engineered nanoparticles

(2013) Zuzana Magdolenova et al.   Nanotoxicology

Cell survival, DNA damage, and oncogenic transformation after a transient and reversible apoptotic response

(2012) Ho Lam Tang et al.   MOLECULAR BIOLOGY OF THE CELL

Inter-laboratory variation in DNA damage using a standard comet assay protocol

(2012) Lykke Forchhammer et al.   MUTAGENESIS

Improvements in the reliability ofin vitrogenotoxicity testing

(2011) David Kirkland   Expert Opinion on Drug Metabolism & Toxicology

Coupling cytotoxicity biomarkers with DNA damage assessment in TK6 human lymphoblast cells

(2010) Jing Shi et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Molecular mechanisms of necroptosis: an ordered cellular explosion

(2010) Peter Vandenabeele et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Autophagy and Metabolism

(2010) J. D. Rabinowitz et al.   SCIENCE

Variation in the measurement of DNA damage by comet assay measured by the ECVAG  inter-laboratory validation trial

(2009) L. Forchhammer et al.   MUTAGENESIS

An ECVAG trial on assessment of oxidative damage to DNA measured by the comet assay

(2009) C. Johansson et al.   MUTAGENESIS

The comet assay in human biomonitoring: gene-environment interactions

(2008) M. Dusinska et al.   MUTAGENESIS