Revealing Angiopep-2/LRP1 Molecular Interaction for Optimal Delivery to Glioblastoma (GBM)

Theranostic Design of Angiopep-2 Conjugated Hyaluronic Acid Nanoparticles (Thera-ANG-cHANPs) for Dual Targeting and Boosted Imaging of Glioma Cells

(2021) Angela Costagliola di Polidoro et al.   Cancers

ANG1005, a brain penetrating peptide-drug conjugate, shows activity in patients with breast cancer with leptomeningeal carcinomatosis and recurrent brain metastases

(2020) Priya Kumthekar et al.   CLINICAL CANCER RESEARCH

Hybrid magnetic nanovectors promote selective glioblastoma cell death through a combined effect of lysosomal membrane permeabilization and chemotherapy

(2020) Carlotta Pucci et al.   ACS Applied Materials & Interfaces

In-silico analysis of ligand-receptor binding patterns of α-MMC, TCS and MAP30 protein to LRP1 receptor

(2020) Bin Liu et al.   JOURNAL OF MOLECULAR GRAPHICS & MODELLING

Angiopep-2/IP10-EGFRvIIIscFv modified nanoparticles and CTL synergistically inhibit malignant glioblastoma

(2018) Xuan Wang et al.   Scientific Reports

PEP-FOLD3: fasterde novostructure prediction for linear peptides in solution and in complex

(2016) Alexis Lamiable et al.   NUCLEIC ACIDS RESEARCH

The role of the low-density lipoprotein receptor–related protein 1 (LRP-1) in regulating blood-brain barrier integrity

(2016) Yahui Zhao et al.   REVIEWS IN THE NEUROSCIENCES

Delivery of a peptide-drug conjugate targeting the blood brain barrier improved the efficacy of paclitaxel against glioma

(2016) Ying Li et al.   Oncotarget

LRP-1-mediated intracellular antibody delivery to the Central Nervous System

(2015) Xiaohe Tian et al.   Scientific Reports

Current approaches to enhance CNS delivery of drugs across the brain barriers

(2014) Cui-Tao Lu et al.   International Journal of Nanomedicine

What are lipoproteins doing in the brain?

(2013) Hong Wang et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Anti-glioblastoma efficacy and safety of paclitaxel-loading Angiopep-conjugated dual targeting PEG-PCL nanoparticles

(2012) Hongliang Xin et al.   BIOMATERIALS

Molecular Docking: A Powerful Approach for Structure-Based Drug Discovery

(2012) Xuan-Yu Meng et al.   Current Computer-Aided Drug Design

The brain targeting mechanism of Angiopep-conjugated poly(ethylene glycol)-co-poly(ɛ-caprolactone) nanoparticles

(2011) Hongliang Xin et al.   BIOMATERIALS

In silico predictions of 3D structures of linear and cyclic peptides with natural and non-proteinogenic residues

(2011) Jérôme Beaufays et al.   JOURNAL OF PEPTIDE SCIENCE

Comparison of five different targeting ligands to enhance accumulation of liposomes into the brain

(2010) Inge van Rooy et al.   JOURNAL OF CONTROLLED RELEASE

Structure of the Minimal Interface Between ApoE and LRP

(2010) Miklos Guttman et al.   JOURNAL OF MOLECULAR BIOLOGY

Transport characteristics of a novel peptide platform for CNS therapeutics

(2009) Yanick Bertrand et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Uptake of ANG1005, A Novel Paclitaxel Derivative, Through the Blood-Brain Barrier into Brain and Experimental Brain Metastases of Breast Cancer

(2009) Fancy C. Thomas et al.   PHARMACEUTICAL RESEARCH

Antitumour activity of ANG1005, a conjugate between paclitaxel and the new brain delivery vector Angiopep-2

(2008) A Régina et al.   BRITISH JOURNAL OF PHARMACOLOGY

425 POSTER ANG1005: Preliminary clinical safety and tolerability in patients with recurrent malignant glioma

(2008) J.P. Castaigne et al.   EJC SUPPLEMENTS