Edaravone Dexborneol Downregulates Neutrophil Extracellular Trap Expression and Ameliorates Blood-Brain Barrier Permeability in Acute Ischemic Stroke

Edaravone dexborneol protects cerebral ischemia reperfusion injury through activating Nrf2/HO‐1 signaling pathway in mice

(2022) Lili Xu et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

Edaravone Dexborneol Treatment Attenuates Neuronal Apoptosis and Improves Neurological Function by Suppressing 4-HNE-Associated Oxidative Stress After Subarachnoid Hemorrhage

(2022) Qian Chen et al.   Frontiers in Pharmacology

Edaravone Dexborneol Versus Edaravone Alone for the Treatment of Acute Ischemic Stroke

(2021) Jie Xu et al.   STROKE

Neutrophil extracellular traps released by neutrophils impair revascularization and vascular remodeling after stroke

(2020) Lijing Kang et al.   Nature Communications

Vascular occlusion by neutrophil extracellular traps in COVID-19

(2020) Moritz Leppkes et al.   EBioMedicine

Peripheral Blood Occludin Level as a Biomarker for Perioperative Cerebral Edema in Patients with Brain Tumors

(2020) Shuhai Shi et al.   DISEASE MARKERS

The vitals of NETs

(2020) Chuyi Tan et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Neutrophil extracellular trap induced by HMGB1 exacerbates damages in the ischemic brain

(2019) Seung-Woo Kim et al.   Acta Neuropathologica Communications

Ginsenoside Rg1 promotes cerebral angiogenesis via the PI3K/Akt/mTOR signaling pathway in ischemic mice

(2019) Junmin Chen et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Dl-3-N-Butylphthalide Alleviates the Blood–Brain Barrier Permeability of Focal Cerebral Ischemia Reperfusion in Mice

(2019) Jiamin Li et al.   NEUROSCIENCE

Would Colloidal Gold Nanocarriers Present An Effective Diagnosis Or Treatment For Ischemic Stroke?

(2019) Hamed Amani et al.   International Journal of Nanomedicine

How is edaravone effective against acute ischemic stroke and amyotrophic lateral sclerosis?

(2018) Kazutoshi Watanabe et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

Compound edaravone alleviates lipopolysaccharide (LPS)-induced acute lung injury in mice

(2017) Zhengping Zhang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

(+)-Borneol improves the efficacy of edaravone against DSS-induced colitis by promoting M2 macrophages polarization via JAK2-STAT3 signaling pathway

(2017) Xiong Zhang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

2014 Chinese guidelines for secondary prevention of ischemic stroke and transient ischemic attack

(2017) Yongjun Wang et al.   International Journal of Stroke

Normobaric Hyperoxia Reduces Blood Occludin Fragments in Rats and Patients With Acute Ischemic Stroke

(2017) Shuhai Shi et al.   STROKE

Neutrophil extracellular traps are increased in patients with acute ischemic stroke: prognostic significance

(2017) Juana Vallés et al.   THROMBOSIS AND HAEMOSTASIS

Blood Occludin Level as a Potential Biomarker for Early Blood Brain Barrier Damage Following Ischemic Stroke

(2017) Rong Pan et al.   Scientific Reports

Cl-Amidine Prevents Histone 3 Citrullination and Neutrophil Extracellular Trap Formation, and Improves Survival in a Murine Sepsis Model

(2016) Bethany M. Biron et al.   Journal of Innate Immunity

The synergetic effect of edaravone and borneol in the rat model of ischemic stroke

(2014) Hai-Yin Wu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Probucol and atorvastatin in combination protect rat brains in MCAO model: Upregulating Peroxiredoxin2, Foxo3a and Nrf2 expression

(2012) Yuanyuan Du et al.   NEUROSCIENCE LETTERS

Netting Neutrophils Induce Endothelial Damage, Infiltrate Tissues, and Expose Immunostimulatory Molecules in Systemic Lupus Erythematosus

(2011) E. Villanueva et al.   JOURNAL OF IMMUNOLOGY

II. Cerebral Infarction/Transient Ischemic Attack (TIA)

(2011) Yukito Shinohara et al.   Journal of Stroke & Cerebrovascular Diseases

Activation of the Raf-MEK-ERK pathway is required for neutrophil extracellular trap formation

(2010) Abdul Hakkim et al.   Nature Chemical Biology

Protection by borneol on cortical neurons against oxygen-glucose deprivation/reperfusion: involvement of anti-oxidation and anti-inflammation through nuclear transcription factor κappaB signaling pathway

(2010) R. Liu et al.   NEUROSCIENCE