Chemotherapy treatment induces pro-invasive changes in liver ECM composition

Chemotherapy-Induced Collagen IV Drives Cancer Cell Motility through Activation of Src and Focal Adhesion Kinase

(2022) Jackson P. Fatherree et al.   CANCER RESEARCH

Collagen biology and non‐invasive biomarkers of liver fibrosis

(2020) Morten A. Karsdal et al.   LIVER INTERNATIONAL

Particle tracking microrheology of cancer cells in living subjects

(2020) Pei-Hsun Wu et al.   Materials Today

Decellularized extracellular matrix scaffolds identify full-length collagen VI as a driver of breast cancer cell invasion in obesity and metastasis

(2020) Andrew L. Wishart et al.   Science Advances

The Role of Fibrosis and Liver-Associated Fibroblasts in the Pathogenesis of Hepatocellular Carcinoma

(2019) Jacopo Baglieri et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Fiber alignment drives changes in architectural and mechanical features in collagen matrices

(2019) Paul V. Taufalele et al.   PLoS One

Chemotherapy-induced metastasis: mechanisms and translational opportunities

(2018) George S. Karagiannis et al.   CLINICAL & EXPERIMENTAL METASTASIS

Chemotherapy induces secretion of exosomes loaded with heparanase that degrades extracellular matrix and impacts tumor and host cell behavior

(2018) Shyam K. Bandari et al.   MATRIX BIOLOGY

Organ-specific metastases obtained by culturing colorectal cancer cells on tissue-specific decellularized scaffolds

(2018) Xi Tian et al.   Nature Biomedical Engineering

Up-regulation of collagen proteins in colorectal liver metastasis compared with normal liver tissue

(2018) Nick A. van Huizen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Assessment of signaling pathway inhibitors and identification of predictive biomarkers in malignant pleural mesothelioma

(2018) Robin Tranchant et al.   LUNG CANCER

Stress-inducible geneAtf3in the noncancer host cells contributes to chemotherapy-exacerbated breast cancer metastasis

(2017) Yi Seok Chang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neoadjuvant chemotherapy induces breast cancer metastasis through a TMEM-mediated mechanism

(2017) George S. Karagiannis et al.   Science Translational Medicine

Extracellular matrix mediators of metastatic cell colonization characterized using scaffold mimics of the pre-metastatic niche

(2016) Brian A. Aguado et al.   Acta Biomaterialia

The extracellular matrix: Tools and insights for the “omics” era

(2016) Alexandra Naba et al.   MATRIX BIOLOGY

Tumor Cell-Driven Extracellular Matrix Remodeling Drives Haptotaxis during Metastatic Progression

(2016) M. J. Oudin et al.   Cancer Discovery

The alterations in the extracellular matrix composition guide the repair of damaged liver tissue

(2016) Mariliis Klaas et al.   Scientific Reports

Collagen type V promotes the malignant phenotype of pancreatic ductal adenocarcinoma

(2015) Sonja Berchtold et al.   CANCER LETTERS

Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver

(2015) Bruno Costa-Silva et al.   NATURE CELL BIOLOGY

Local 3D matrix microenvironment regulates cell migration through spatiotemporal dynamics of contractility-dependent adhesions

(2015) Andrew D. Doyle et al.   Nature Communications

Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver

(2014) Alexandra Naba et al.   BMC CANCER

Tissue mechanics modulate microRNA-dependent PTEN expression to regulate malignant progression

(2014) Janna K Mouw et al.   NATURE MEDICINE

LOX-Mediated Collagen Crosslinking Is Responsible for Fibrosis-Enhanced Metastasis

(2013) T. R. Cox et al.   CANCER RESEARCH

Bi-Directional Signaling: Extracellular Matrix and Integrin Regulation of Breast Tumor Progression

(2013) Scott Gehler et al.   CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION

Treatment-induced host-mediated mechanisms reducing the efficacy of antitumor therapies

(2013) L G M Daenen et al.   ONCOGENE

Gene Expression Profiling of Early Hepatic Stellate Cell Activation Reveals a Role for Igfbp3 in Cell Migration

(2013) Inge Mannaerts et al.   PLoS One

Intravital Microscopy Through an Abdominal Imaging Window Reveals a Pre-Micrometastasis Stage During Liver Metastasis

(2012) L. Ritsma et al.   Science Translational Medicine

Chemotherapy Enhances Metastasis Formation via VEGFR-1-Expressing Endothelial Cells

(2011) L. G. M. Daenen et al.   CANCER RESEARCH

Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer

(2011) T. R. Cox et al.   Disease Models & Mechanisms

Collagen V is a dominant regulator of collagen fibrillogenesis: dysfunctional regulation of structure and function in a corneal-stroma-specific Col5a1-null mouse model

(2011) M. Sun et al.   JOURNAL OF CELL SCIENCE

Extracellular matrix: A gatekeeper in the transition from dormancy to metastatic growth

(2010) Dalit Barkan et al.   EUROPEAN JOURNAL OF CANCER

Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling

(2009) Kandice R. Levental et al.   CELL

Cellular Sources of Extracellular Matrix in Hepatic Fibrosis

(2008) Rebecca G. Wells   Clinics in Liver Disease